Abstract: Spherical, magnetizable polyvinyl alcohol microparticles, methods for their production, and use thereof are provided in the invention. The microparticles are especially useful for diagnostic purposes. The method enables the production of microparticles having a particle size distribution in the range of 0.5 to 3 ?m, and includes the following steps, dispersing a nanoparticulate, magnetizable material in an aqueous phase which contains polyvinyl alcohol in dissolved form, adding the aqueous phase to an organic phase, immiscible with said aqueous phase and containing at least one emulsifier, producing an emulsion by stirring at a temperature of 25° C. or higher, and adding at least one water-soluble crosslinking agent while stirring is continued.

Abstract: Spherical, magnetizable polyvinyl alcohol microparticles, methods for their production, and use thereof are provided in the invention. The microparticles are especially useful for diagnostic purposes. The method enables the production of microparticles having a particle size distribution in the range of 0.5 to 3 ?m, and includes the following steps, dispersing a nanoparticulate, magnetizable material in an aqueous phase which contains polyvinyl alcohol in dissolved form, adding the aqueous phase to an organic phase, immiscible with said aqueous phase and containing at least one emulsifier, producing an emulsion by stirring at a temperature of 25° C. or higher, and adding at least one water-soluble crosslinking agent while stirring is continued.

Abstract: The present invention relates to magnetic, polymeric polyvinylalcohol-based carrier materials. The surface of said materials is at least partially silanised. The invention also relates to a method for silanising the surface of such materials and to the use of the magnetic, silanised carrier materials for isolating biological material, preferably nucleic acids.