Patents by Inventor J. Tyler Martin

J. Tyler Martin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TRITERPENE SAPONIN SYNTHESIS, INTERMEDIATES AND ADJUVANT COMBINATIONS
    Publication number: 20230357300
    Abstract: The present application relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, and intermediates thereto. The application also provides pharmaceutical compositions comprising compounds of the present invention and methods of using said compounds or compositions in the treatment of and immunization for infectious diseases.
    Type: Application
    Filed: March 22, 2023
    Publication date: November 9, 2023
    Applicant: ADJUVANCE TECHNOLOGIES, INC.
    Inventors: Amanda CHAN, Jeffrey GARDNER, Lars NORDSTROEM, William WALKOWICZ, J Tyler MARTIN, Weidong ZHANG
  • VACCINES, VACCINE PRIMING, AND ANTIGEN DOSE SPARING
    Publication number: 20230263886
    Abstract: The present application relates to new vaccines, improved vaccine priming, and antigen dose sparing in connection with triterpene glycoside saponin-derived adjuvants, salt forms thereof, and pharmaceutical compositions, as well as related methods.
    Type: Application
    Filed: June 17, 2021
    Publication date: August 24, 2023
    Inventors: J. Tyler MARTIN, Eric Jon FARRIS, Anna Therese LAMPE
  • TRITERPENE SAPONIN ANALOGUES
    Publication number: 20230219991
    Abstract: The present application relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, and intermediates thereto. The application also provides pharmaceutical compositions comprising compounds of the present invention and methods of using said compounds or compositions in the treatment of and immunization for infectious diseases.
    Type: Application
    Filed: March 8, 2023
    Publication date: July 13, 2023
    Applicants: ADJUVANCE TECHNOLOGIES, INC., MEMORIAL SLOAN KETTERING CANCER CENTER
    Inventors: David Y. GIN, Eric CHEA, Alberto FERNANDEZ-TEJADA, Jeffrey GARDNER, Jason LEWIS, Philip LIVINGSTON, J. Tyler MARTIN, Lars NORDSTROEM, Naga Vara Kishore PILLARSETTY, Govind RAGUPATHI, Derek TAN
  • ADJUVANT COMPOUNDS, SALT FORMS, AND FORMULATIONS
    Publication number: 20230128815
    Abstract: The present application relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, and intermediates thereto. The application also provides salt forms, formulations, and pharmaceutical compositions comprising compounds of the present invention and methods of using said compounds, salt forms, or compositions in the treatment of and immunization for infectious diseases.
    Type: Application
    Filed: March 23, 2021
    Publication date: April 27, 2023
    Inventors: J Tyler MARTIN, Jared William WENGER, Stephan D PARENT, Courtney S JOHNSON, Eric Jon FARRIS, Gui LIU
  • VARICELLA ZOSTER
    Publication number: 20220409721
    Abstract: The present application relates to compositions capable of inducing an immune response against Varicella zoster virus, methods of administering such compositions, and methods of producing such compositions.
    Type: Application
    Filed: November 4, 2020
    Publication date: December 29, 2022
    Applicant: ADJUVANCE TECHNOLOGIES, INC.
    Inventors: J Tyler MARTIN, Jared William WENGER, Eric Jon FARRIS, Patrick J FRENCHICK (Deceased), Anna Therese LAMPE
  • TRITERPENE SAPONIN ANALOGUES
    Publication number: 20220184207
    Abstract: The present application relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, and intermediates thereto. The application also provides pharmaceutical compositions comprising compounds of the present invention and methods of using said compounds or compositions in the treatment of and immunization for infectious diseases and cancers.
    Type: Application
    Filed: March 4, 2022
    Publication date: June 16, 2022
    Applicant: ADJUVANCE TECHNOLOGIES, INC.
    Inventors: J Tyler MARTIN, Jeffrey GARDNER
  • Triterpene saponin analogues
    Patent number: 11324821
    Abstract: The present application relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, and intermediates thereto. The application also provides pharmaceutical compositions comprising compounds of the present invention and methods of using said compounds or compositions in the treatment of and immunization for infectious diseases and cancers.
    Type: Grant
    Filed: October 15, 2018
    Date of Patent: May 10, 2022
    Assignee: ADJUVANCE TECHNOLOGIES, INC.
    Inventors: J Tyler Martin, Jeffrey Gardner
  • TRITERPENE SAPONIN SYNTHESIS, INTERMEDIATES AND ADJUVANT COMBINATIONS
    Publication number: 20210299237
    Abstract: The present application relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, and intermediates thereto. The application also provides pharmaceutical compositions comprising compounds of the present invention and methods of using said compounds or compositions in the treatment of and immunization for infectious diseases.
    Type: Application
    Filed: April 13, 2018
    Publication date: September 30, 2021
    Applicant: ADJUVANCE TECHNOLOGIES, INC.
    Inventors: Amanda CHAN, Jeffrey GARDNER, Lars NORDSTROEM, William WALKOWICZ, J Tyler MARTIN, Weidong Zhang
  • TRITERPENE SAPONIN ANALOGUES
    Publication number: 20210283248
    Abstract: The present application relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, and intermediates thereto. The application also provides pharmaceutical compositions comprising compounds of the present invention and methods of using said compounds or compositions in the treatment of and immunization for infectious diseases.
    Type: Application
    Filed: April 25, 2018
    Publication date: September 16, 2021
    Applicants: Adjuvance Technologies, Inc., Memorial Sloan Kettering Cancer Center
    Inventors: Philip LIVINGSTON, Govind RAGUPATHI, Jeffrey GARDNER, J Tyler MARTIN
  • Triterpene saponin analogues
    Patent number: 10906926
    Abstract: The present application relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, and intermediates thereto. The application also provides pharmaceutical compositions comprising compounds of the present invention and methods of using said compounds or compositions in the treatment of and immunization for infectious diseases.
    Type: Grant
    Filed: March 23, 2020
    Date of Patent: February 2, 2021
    Assignees: ADJUVANCE TECHNOLOGIES, INC., MEMORIAL SLOAN KETTERING CANCER
    Inventors: David Y. Gin, Eric Chea, Alberto Fernandez-Tejada, Jeffrey Gardner, Jason Lewis, Philip Livingston, J. Tyler Martin, Lars Nordstroem, Naga Vara Kishore Pillarsetty, Govind Ragupathi, Derek Tan
  • TRITERPENE SAPONIN ANALOGUES
    Publication number: 20210002316
    Abstract: The present application relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, and intermediates thereto. The application also provides pharmaceutical compositions comprising compounds of the present invention and methods of using said compounds or compositions in the treatment of and immunization for infectious diseases.
    Type: Application
    Filed: August 27, 2020
    Publication date: January 7, 2021
    Applicants: ADJUVANCE TECHNOLOGIES, INC., MEMORIAL SLOAN KETTERING CANCER CENTER
    Inventors: David Y. GIN, Eric CHEA, Alberto FERNANDEZ-TEJADA, Jeffrey GARDNER, Jason LEWIS, Philip LIVINGSTON, J. Tyler MARTIN, Lars NORDSTROEM, Naga Vara Kishore PILLARSETTY, Govind RAGUPATHI, Derek TAN
  • TRITERPENE SAPONIN ANALOGUES
    Publication number: 20200261571
    Abstract: The present application relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, and intermediates thereto. The application also provides pharmaceutical compositions comprising compounds of the present invention and methods of using said compounds or compositions in the treatment of and immunization for infectious diseases and cancers.
    Type: Application
    Filed: October 15, 2018
    Publication date: August 20, 2020
    Applicant: ADJUVANCE TECHNOLOGIES, INC.
    Inventors: J Tyler MARTIN, Jeffrey GARDNER
  • TRITERPENE SAPONIN ANALOGUES
    Publication number: 20200239509
    Abstract: The present application relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, and intermediates thereto. The application also provides pharmaceutical compositions comprising compounds of the present invention and methods of using said compounds or compositions in the treatment of and immunization for infectious diseases.
    Type: Application
    Filed: March 23, 2020
    Publication date: July 30, 2020
    Applicants: ADJUVANCE TECHNOLOGIES, INC., MEMORIAL SLOAN KETTERING CANCER CENTER
    Inventors: David Y. GIN (Deceased), Eric CHEA, Alberto FERNANDEZ-TEJADA, Jeffrey GARDNER, Jason LEWIS, Philip LIVINGSTON, J. Tyler MARTIN, Lars NORDSTROEM, Naga Vara Kishore PILLARSETTY, Govind RAGUPATHI, Derek TAN
  • TRITERPENE SAPONIN ANALOGUES
    Publication number: 20200164065
    Abstract: The present application relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, and intermediates thereto. The application also provides pharmaceutical compositions comprising compounds of the present invention and methods of using said compounds or compositions in the treatment of and immunization for infectious diseases.
    Type: Application
    Filed: April 25, 2018
    Publication date: May 28, 2020
    Applicant: ADJUVANCE TECHNOLOGIES, INC.
    Inventors: Jeffrey GARDNER, Philip LIVINGSTON, J Tyler MARTIN
  • TRITERPENE SAPONIN ANALOGUES
    Publication number: 20180327436
    Abstract: The present application relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, and intermediates thereto. The application also provides pharmaceutical compositions comprising compounds of the present invention and methods of using said compounds or compositions in the treatment of and immunization for infectious diseases.
    Type: Application
    Filed: November 4, 2016
    Publication date: November 15, 2018
    Applicant: ADJUVANCE TECHNOLOGIES, INC.
    Inventors: David Y. GIN (Deceased), Eric CHEA, Alberto FERNANDEZ-TEJADA, Jeffrey GARDNER, Jason LEWIS, Philip LIVINGSTON, J. Tyler MARTIN, Lars NORDSTROEM, Naga Vara Kishore PILLARSETTY, Govind RAGUPATHI, Derek TAN
  • Methods and compositions for treating neuropathic and neurodegenerative conditions
    Publication number: 20110281937
    Abstract: Disclosed herein are engineered zinc finger proteins which modulate transcription of the gene encoding vascular endothelial growth factor-A (VEGF-A) and other genes encoding products with neurotrophic activities. Also disclosed are methods for the use of these engineered zinc finger proteins in the treatment of neuropathy (including diabetic neuropathy), and other types of neural injury and neurodegeneration.
    Type: Application
    Filed: January 3, 2011
    Publication date: November 17, 2011
    Inventors: J. Tyler Martin, Edward J. Rebar
  • Methods and compositions for treating neuropathic and neurodegenerative conditions
    Publication number: 20100256221
    Abstract: Disclosed herein are engineered zinc finger proteins which modulate transcription of the gene encoding vascular endothelial growth factor-A (VEGF-A) and other genes encoding products with neurotrophic activities. Also disclosed are methods for the use of these engineered zinc finger proteins in the treatment of neuropathy (including diabetic neuropathy), and other types of neural injury and neurodegeneration.
    Type: Application
    Filed: October 8, 2009
    Publication date: October 7, 2010
    Inventor: J. Tyler Martin