Patents by Inventor Jaby Jacob

Jaby Jacob has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FORMULATIONS
    Publication number: 20190345238
    Abstract: The invention provides a formulation comprising a buffer with a pH from about 4.0 to about 6.0, proline and an effective amount of a polypeptide. The polypeptide can be an antibody. The specification also provides methods of preparing the formulation, a kit containing the formulation and methods of using the formulation.
    Type: Application
    Filed: May 22, 2019
    Publication date: November 14, 2019
    Applicant: AMGEN INC.
    Inventors: Jaby JACOB, Masazumi MATSUMURA, Yatin GOKARN, David BREMS
  • Refolding of granulocyte colony stimulating factor
    Patent number: 9982012
    Abstract: Provided is a method of refolding of recombinant GCSF that minimizes the generation of oxidized forms of GCSF by optimizing the refolding of inclusion bodies containing recombinant GCSF.
    Type: Grant
    Filed: March 28, 2014
    Date of Patent: May 29, 2018
    Assignee: DR. REDDY'S LABORATORIES LIMITED
    Inventors: Bharata Ratnam Parayitam, Ravikant Devakate, Neeraj Narayanan, Gopinath Govindarajan, Vivek Arthanari, Jaby Jacob
  • REFOLDING OF PROTEINS
    Publication number: 20160031932
    Abstract: Provided is a method of refolding of recombinant GCSF that minimizes the generation of oxidized forms of GCSF by optimizing the refolding of inclusion bodies containing recombinant GCSF.
    Type: Application
    Filed: March 28, 2014
    Publication date: February 4, 2016
    Inventors: Bharata Ratnam PARAYITAM, Ravikant Ramchandra Niwas DEVAKATE, Neeraj NARAYANAN, Gopinath GOVINDARAJAN, Vivek ARTHANARI, Jaby JACOB
  • FORMULATIONS
    Publication number: 20150315271
    Abstract: The invention provides a formulation comprising a buffer with a pH from about 4.0 to about 6.0, proline and an effective amount of a polypeptide. The polypeptide can be an antibody. The specification also provides methods of preparing the formulation, a kit containing the formulation and methods of using the formulation.
    Type: Application
    Filed: May 5, 2015
    Publication date: November 5, 2015
    Applicant: AMGEN INC.
    Inventors: Jaby JACOB, Masazumi MATSUMURA, Yatin GOKARN, David BREMS
  • SINGLE STEP FRACTIONATION METHOD
    Publication number: 20150065689
    Abstract: Single step method of enriching highly sialylated variant/s of a protein by use of a strong ion exchange chromatography support and a pH gradient in absence of any salt gradient.
    Type: Application
    Filed: April 8, 2013
    Publication date: March 5, 2015
    Applicant: DR. REDDY'S LABORATORIES LIMITED
    Inventors: Ashish K Patra, Venkata Ramireddy Yeturu, Jaby Jacob
  • Formulations
    Publication number: 20080213282
    Abstract: The invention provides a formulation comprising a buffer with a pH from about 4.0 to about 6.0, proline and an effective amount of a polypeptide. The polypeptide can be an antibody. The specification also provides methods of preparing the formulation, a kit containing the formulation and methods of using the formulation.
    Type: Application
    Filed: December 19, 2007
    Publication date: September 4, 2008
    Inventors: Jaby Jacob, Masazumi Matsumura, Yatin Gokarn, David Brems