Patents by Inventor Jacek Stalewski

Jacek Stalewski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANGIOTENSIN-1-RECEPTOR ANTAGONISTS
    Publication number: 20200102348
    Abstract: In one aspect, this disclosure features compounds of formula (I) or a pharmaceutically acceptable salt thereof: AA1-Arg-Val-AA4-AA5-His-Pro-AA8-OH ??(I), in which AA1, AA4, AA5, and AA8 are defined in the specification. The compounds of formula (I) can be used to treat hypertension (e.g., hypertension induced by pregnancy), preeclampsia, or a renal disease induced by pregnancy.
    Type: Application
    Filed: July 8, 2019
    Publication date: April 2, 2020
    Applicant: FERRING B.V.
    Inventors: Jacek STALEWSKI, Edward Earl Cable
  • Angiotensin-1-receptor antagonists
    Patent number: 10344054
    Abstract: Compounds of formula (I) and pharmaceutically acceptable salts thereof are described: AA1-Arg-Val-AA4-AA5-His-Pro-AA8-OH??(I), in which AA1, AA4, AA5, and AA8 are defined in the specification. The compounds of formula (I) can be used to treat hypertension (e.g., hypertension induced by pregnancy), preeclampsia, or a renal disease induced by pregnancy.
    Type: Grant
    Filed: June 2, 2017
    Date of Patent: July 9, 2019
    Assignee: FERRING B.V.
    Inventors: Jacek Stalewski, Edward Earl Cable
  • Angiotensin-1-Receptor Antagonists
    Publication number: 20170349629
    Abstract: In one aspect, this disclosure features compounds of formula (I) or a pharmaceutically acceptable salt thereof: AA1-Arg-Val-AA4-AA5-His-Pro-AA8-OH ??(I), in which AA1, AA4, AA5, and AA8 are defined in the specification. The compounds of formula (I) can be used to treat hypertension (e.g., hypertension induced by pregnancy), preeclampsia, or a renal disease induced by pregnancy.
    Type: Application
    Filed: June 2, 2017
    Publication date: December 7, 2017
    Inventors: Jacek Stalewski, Edward Earl Cable
  • Methods for making intermediates and oxytocin analogues
    Patent number: 7816489
    Abstract: More efficient and/or economical methods for synthesizing heptapeptide alcohol analogs of oxytocin are provided along with novel intermediates which are useful in synthesizing such oxytocin analogs. Efficient and economical methods for synthesizing intermediates useful in synthesizing these oxytocin analogs are also provided.
    Type: Grant
    Filed: October 30, 2007
    Date of Patent: October 19, 2010
    Assignee: Ferring B.V.
    Inventors: Kazimierz Wisniewski, Jacek Stalewski, Guangcheng Jiang
  • AMIDE OR THIOAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF PAIN
    Publication number: 20100105777
    Abstract: The present invention relates to novel compounds, pharmaceutical compositions comprising the same, use of said compounds for the manufacture of a medicament for treatment of pain and disorders related thereto as well as a method for treatment of pain and disorders related thereto, wherein said compounds are administered. The compounds are represented by the general formula (I), as further defined in the specification.
    Type: Application
    Filed: February 23, 2009
    Publication date: April 29, 2010
    Applicant: CARA THERAPEUTICS, INC.
    Inventors: Chia-Ping CHANG, Jacek STALEWSKI, Pierre J-M. RIVIERE, Kazimierz A. WISNIEWSKI, Claudio D. SCHTEINGART
  • Amide or thioamide derivatives and their use in the treatment of pain
    Patent number: 7504538
    Abstract: The present invention relates to novel compounds, pharmaceutical compositions comprising the same, use of said compounds for the manufacture of a medicament for treatment of pain and disorders related thereto as well as a method for treatment of pain and disorders related thereto, wherein said compounds are administered. The compounds are represented by the general formula (I), as further defined in the specification.
    Type: Grant
    Filed: October 14, 2004
    Date of Patent: March 17, 2009
    Assignee: Cara Therapeutics, Inc.
    Inventors: Chia-Ping Chang, Jacek Stalewski, Piere J-M. Riviere, Kazimierz A. Wisniewski, Claudio D. Schteingart
  • METHODS FOR MAKING INTERMEDIATES AND OXYTOCIN ANALOGUES
    Publication number: 20080177035
    Abstract: More efficient and/or economical methods for synthesizing heptapeptide alcohol analogs of oxytocin are provided along with novel intermediates which are useful in synthesizing such oxytocin analogs. Efficient and economical methods for synthesizing intermediates useful in synthesizing these oxytocin analogs are also provided.
    Type: Application
    Filed: October 30, 2007
    Publication date: July 24, 2008
    Applicant: FERRING B.V.
    Inventors: Kazimierz Wisniewski, Jacek Stalewski, Guangcheng Jiang
  • Methods for making intermediates and oxytocin analogues
    Patent number: 7304181
    Abstract: More efficient and/or economical methods for synthesizing heptapeptide alcohol analogs of oxytocin are provided along with novel intermediates which are useful in synthesizing such oxytocin analogs. Efficient and economical methods for synthesizing intermediates useful in synthesizing these oxytocin analogs are also provided.
    Type: Grant
    Filed: July 14, 2006
    Date of Patent: December 4, 2007
    Assignee: Ferring BV
    Inventors: Kazimierz Wisniewski, Jacek Stalewski, Guangcheng Jiang
  • Amide or thioamide derivatives and their use in the treatment of pain
    Publication number: 20070197653
    Abstract: The present invention relates to novel compounds, pharmaceutical compositions comprising the same, use of said compounds for the manufacture of a medicament for treatment of pain and disorders related thereto as well as a method for treatment of pain and disorders related thereto, wherein said compounds are administered. The compounds are represented by the general formula (I), as further defined in the specification.
    Type: Application
    Filed: October 14, 2004
    Publication date: August 23, 2007
    Applicant: CARA THERAPEUTICS, INC.
    Inventors: Chia-Ping Chang, Jacek Stalewski, Pierre Riviere, Kazimierz Wesniewski, Claudio Schteingart
  • METHODS FOR MAKING INTERMEDIATES AND OXYTOCIN ANALOGUES
    Publication number: 20060247157
    Abstract: More efficient and/or economical methods for synthesizing heptapeptide alcohol analogs of oxytocin are provided along with novel intermediates which are useful in synthesizing such oxytocin analogs. Efficient and economical methods for synthesizing intermediates useful in synthesizing these oxytocin analogs are also provided.
    Type: Application
    Filed: July 14, 2006
    Publication date: November 2, 2006
    Applicant: FERRING BV
    Inventors: Kazimierz Wisniewski, Jacek Stalewski, Guangcheng Jiang
  • Intermediates and methods for making heptapeptide oxytocin analogues
    Patent number: 7091314
    Abstract: More efficient and/or economical methods for synthesizing heptapeptide alcohol analogs of oxytocin are provided along with novel intermediates which are useful in synthesizing such oxytocin analogs. Efficient and economical methods for synthesizing intermediates useful in synthesizing these oxytocin analogs are also provided.
    Type: Grant
    Filed: July 8, 2004
    Date of Patent: August 15, 2006
    Assignee: Ferring BV
    Inventors: Kazimierz Wisniewski, Jacek Stalewski, Guangcheng Jiang
  • Intermediates and methods for making heptapeptide oxytocin analogues
    Publication number: 20040248776
    Abstract: More efficient and/or economical methods for synthesizing heptapeptide alcohol analogs of oxytocin are provided along with novel intermediates which are useful in synthesizing such oxytocin analogs. Efficient and economical methods for synthesizing intermediates useful in synthesizing these oxytocin analogs are also provided.
    Type: Application
    Filed: July 8, 2004
    Publication date: December 9, 2004
    Applicant: Ferring B.V.
    Inventors: Kazimierz Wisniewski, Jacek Stalewski, Guangcheng Jiang