Patents by Inventor Jack Hinson

Jack Hinson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Acetaminophen adducts and methods of use thereof
    Patent number: 11987834
    Abstract: The present disclosure relates to acetaminophen protein adducts and methods of diagnosing acetaminophen toxicity using the acetaminophen protein adducts.
    Type: Grant
    Filed: June 6, 2019
    Date of Patent: May 21, 2024
    Assignee: BioVentures, LLC
    Inventors: Laura P. James, Jack Hinson, Dean Roberts, Pritmohinder S. Gill
  • Anti-acetaminophen antibodies and acetaminophen protein adducts
    Patent number: 11566081
    Abstract: The present disclosure provides isolated antibodies that bind to acetaminophen-protein adducts that are useful in the detection and diagnosis of acetaminophen-induced toxicity.
    Type: Grant
    Filed: January 10, 2020
    Date of Patent: January 31, 2023
    Assignees: BioVentures, LLC, Arkansas Children's Research Institute
    Inventors: Dean W. Roberts, Laura James, Jack Hinson
  • ANTI-ACETAMINOPHEN ANTIBODIES AND ACETAMINOPHEN PROTEIN ADDUCTS
    Publication number: 20200131278
    Abstract: The present disclosure provides isolated antibodies that bind to acetaminophen-protein adducts that are useful in the detection and diagnosis of acetaminophen-induced toxicity.
    Type: Application
    Filed: January 10, 2020
    Publication date: April 30, 2020
    Inventors: Dean W. Roberts, Laura James, Jack Hinson
  • Anti-acetaminophen antibodies and acetaminophen protein adducts
    Patent number: 10570216
    Abstract: The present disclosure provides isolated antibodies that bind to acetaminophen-protein adducts that are useful in the detection and diagnosis of acetaminophen-induced toxicity.
    Type: Grant
    Filed: December 3, 2015
    Date of Patent: February 25, 2020
    Assignees: BioVentures, LLC, Arkansas Children's Research Institute
    Inventors: Dean W. Roberts, Laura James, Jack Hinson
  • ACETAMINOPHEN ADDUCTS AND METHODS OF USE THEREOF
    Publication number: 20190300931
    Abstract: The present disclosure relates to acetaminophen protein adducts and methods of diagnosing acetaminophen toxicity using the acetaminophen protein adducts.
    Type: Application
    Filed: June 6, 2019
    Publication date: October 3, 2019
    Inventors: Laura P. James, Jack Hinson, Dean Roberts, Pritmohinder S. Gill
  • Acetaminophen adducts and methods of use thereof
    Patent number: 10351897
    Abstract: The present disclosure relates to acetaminophen protein adducts and methods of diagnosing acetaminophen toxicity using the acetaminophen protein adducts. The present disclosure provides acetaminophen (APAP)-protein adducts and methods of detecting acetaminophen-induced toxicity in a subject using APAP-protein adducts. One aspect of the present disclosure provides an APAP-protein adduct for diagnosing acetaminophen-induced toxicity. According to the present disclosure, the inventors have identified proteins that are modified by N-acetyl-pbenzoquinoneimine (NAPQI) in subjects with acetaminophen-induced toxicity. Non-limiting examples of proteins modified by NAPQI include betaine-homocysteine S-methyltransferase 1, cytoplasmic aspartate aminotransferase, 1,4-alpha-glucan branching enzyme, formimidoyltransferase-cyclodeaminase, and dystrophin.
    Type: Grant
    Filed: February 13, 2015
    Date of Patent: July 16, 2019
    Assignee: BioVentures, LLC
    Inventors: Laura P. James, Jack Hinson, Dean Roberts, Pritmohinder S. Gill
  • ANTI-ACETAMINOPHEN ANTIBODIES AND ACETAMINOPHEN PROTEIN ADDUCTS
    Publication number: 20170362340
    Abstract: The present disclosure provides isolated antibodies that bind to acetaminophen-protein adducts that are useful in the detection and diagnosis of acetaminophen-induced toxicity.
    Type: Application
    Filed: December 3, 2015
    Publication date: December 21, 2017
    Inventors: Dean W. Roberts, Laura James, Jack Hinson
  • ACETAMINOPHEN ADDUCTS AND METHODS OF USE THEREOF
    Publication number: 20170175166
    Abstract: The present disclosure relates to acetaminophen protein adducts and methods of diagnosing acetaminophen toxicity using the acetaminophen protein adducts. The present disclosure provides acetaminophen (APAP)-protein adducts and methods of detecting acetaminophen-induced toxicity in a subject using APAP-protein adducts. One aspect of the present disclosure provides an APAP-protein adduct for diagnosing acetaminophen-induced toxicity. According to the present disclosure, the inventors have identified proteins that are modified by N-acetyl-pbenzoquinoneimine (NAPQI) in subjects with acetaminophen-induced toxicity. Non-limiting examples of proteins modified by NAPQI include betaine-homocysteine 5-methyltransferase 1, cytoplasmic aspartate aminotransferase, 1,4-alpha-glucan branching enzyme, formimidoyltransferase-cyclodeaminase, and dystrophin.
    Type: Application
    Filed: February 13, 2015
    Publication date: June 22, 2017
    Inventors: Laura P. James, Jack Hinson, Dean Roberts, Pritmohinder S. Gill
  • ACETAMINOPHEN-PROTEIN ADDUCT ASSAY DEVICE AND METHOD
    Publication number: 20120301897
    Abstract: The present invention describes devices and methods for detecting and measuring the amount of acetaminophen-protein adducts in a sample.
    Type: Application
    Filed: August 3, 2012
    Publication date: November 29, 2012
    Applicant: BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS
    Inventors: Laura James, Dean Roberts, Jack A. Hinson
  • ACETAMINOPHEN-PROTEIN ADDUCT ASSAY DEVICE AND METHOD
    Publication number: 20090263839
    Abstract: The present invention describes devices and methods for detecting and measuring the amount of acetaminophen-protein adducts in a sample.
    Type: Application
    Filed: April 21, 2009
    Publication date: October 22, 2009
    Applicants: Board of Trustees of the University of Arkansas, Arkansas Children's Hospital Research Institute, Inc.
    Inventors: Laura James, Dean Roberts, Jack A. Hinson