Patents by Inventor Jackson T. Stephens, JR.

Jackson T. Stephens, JR. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR TREATING SOLID CANCER
    Publication number: 20230398190
    Abstract: Compositions and methods for treating solid cancer are provided. Specifically, the disclosure provides compositions comprising haloperoxidases, and methods comprising administering such compositions, for treating solid cancer.
    Type: Application
    Filed: October 1, 2021
    Publication date: December 14, 2023
    Inventors: Robert C. Allen, Jackson T. Stephens, Jr.
  • OXIDASE-BASED CHEMILUMINESCENCE ASSAY OF PHAGOCYTIC LEUKOCYTES IN WHOLE BLOOD AND BODY FLUIDS APPLICABLE TO POINT-OF-CARE (POC) DIAGNOSTIC TESTING POINT-OF-CARE (POC) MEASUREMENT OF ABSOLUTE NEUTROPHIL FUNCTION (ANF)
    Publication number: 20220308046
    Abstract: A method for estimating a number of phagocytes in a body fluid of an animal includes stimulating NADPH oxidase activity of the phagocytes; and quantifying a resulting reductive deoxygenation of a chemiluminigenic substrate by an emitted chemiluminescence of the chemiluminigenic substrate using an instrument capable of measuring light. The NADPH oxidase activity of the phagocytes is preferably stimulated by an immunologic or chemical capable of activating a respiratory burst by the phagocytes, and by a stimulus in solution or coated to a surface contacted by the phagocytes. The stimulus is preferably phorbol myristate acetate (PMA). The animal is preferably human, and the body fluid is preferably blood and/or spinal fluid. The phagocytes are preferably neutrophil leukocytes, and the chemiluminigenic substrate is preferably lucigenin (N,N?-dimethyl-9,9?-biacridinium dinitrate). Also provided is a method of treatment based on the estimation method.
    Type: Application
    Filed: June 10, 2020
    Publication date: September 29, 2022
    Inventors: Robert C. Allen, John C. Allen, Jackson T. Stephens Jr.
  • Bioactive heme-haloperoxidase compositions and methods of their use
    Patent number: 9814234
    Abstract: Compositions comprising a heme-haloperoxidase and an amino alcohol effective for killing or inhibiting the growth of pathogenic microorganisms in the presence of a peroxide and halide and methods of use are provided.
    Type: Grant
    Filed: January 9, 2015
    Date of Patent: November 14, 2017
    Assignee: EXOXEMIS, INC.
    Inventors: Jackson T. Stephens, Jr., Matthew J. Pete
  • Eosinophil peroxidase compositions and methods of their use
    Patent number: 9782459
    Abstract: Eosinophil peroxidase compositions and methods of their use for killing and/or inhibiting the growth of susceptible microorganisms are provided. The compositions include an eosinophil peroxidase, a peroxide or peroxide source, and amino acids glycine, L-alanine, and L-proline.
    Type: Grant
    Filed: January 8, 2014
    Date of Patent: October 10, 2017
    Assignee: EXOXEMIS, INC.
    Inventors: Jackson T. Stephens, Jr., Matthew J. Pete
  • BIOACTIVE HEME-HALOPEROXIDASE COMPOSITIONS AND METHODS OF THEIR USE
    Publication number: 20150196025
    Abstract: Compositions comprising a heme-haloperoxidase and an amino alcohol effective for killing or inhibiting the growth of pathogenic microorganisms in the presence of a peroxide and halide and methods of use are provided.
    Type: Application
    Filed: January 9, 2015
    Publication date: July 16, 2015
    Inventors: Jackson T. Stephens, JR., Matthew J. Pete
  • EOSINOPHIL PEROXIDASE COMPOSITIONS AND METHODS OF THEIR USE
    Publication number: 20140120076
    Abstract: Eosinophil peroxidase compositions and methods of their use for killing and/or inhibiting the growth of susceptible microorganisms are provided. The compositions include an eosinophil peroxidase, a peroxide or peroxide source, and amino acids glycine, L-alanine, and L-proline.
    Type: Application
    Filed: January 8, 2014
    Publication date: May 1, 2014
    Applicant: Exoxemis, Inc.
    Inventors: Jackson T. Stephens, JR., Matthew J. Pete