Patents by Inventor Jacob Flyvholm Cramer

Jacob Flyvholm Cramer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230404088
    Abstract: This invention relates to polypeptides, more specifically non-maltogenic alpha-amylase and glucoamylase polypeptides, and their uses in providing baked products with enhanced resilience.
    Type: Application
    Filed: September 21, 2021
    Publication date: December 21, 2023
    Inventors: Jacob Flyvholm Cramer, Morgan Louise Gifford, Svend Haaning, Lene Kragh, Vinni Høyer Lillelund, Donald E. Ward
  • Publication number: 20230332130
    Abstract: The present disclosure provides methods, compositions, apparatuses and kits comprising ALDC enzymes having a better stability and/or activity, and, optionally, the yield of ALDC enzymes which can be recovered from microorganisms is improved. In some embodiments, the present disclosure provides methods, apparatuses, compositions and kits for the use of metal ions to increase stability and/or activity, and which further can be used to recover the enzymes from microorganisms in improved yields.
    Type: Application
    Filed: March 17, 2023
    Publication date: October 19, 2023
    Inventors: Jacob Flyvholm Cramer, Lene Kragh, Anja Hemmingsen Kellett-Smith, Tove Bladt, Sang-Kyu Lee
  • Publication number: 20230301335
    Abstract: A spray-dried composition comprising an enzyme which is a ?-galactosidase having transgalactosylating activity and a maltodextrin and/or sodium chloride.
    Type: Application
    Filed: May 16, 2023
    Publication date: September 28, 2023
    Inventors: Morten Krog Larsen, Jens Damgaard, Bjarne Larsen, Jacob Flyvholm Cramer
  • Publication number: 20230295601
    Abstract: The present disclosure provides methods, compositions, apparatuses, and kits comprising ALDC enzymes having a better stability and activity, and which further can be recovered from microorganisms in improved yields.
    Type: Application
    Filed: February 28, 2023
    Publication date: September 21, 2023
    Inventors: Jacob Flyvholm Cramer, Anja Hemmingsen Kellett-Smith, Lene Kragh, Bjarne Larsen
  • Publication number: 20230167386
    Abstract: The present invention provides methods of mashing high tannin adjuncts. More specifically, high tannin adjuncts can be refractory to exogenous enzymes used in barley malt brewing. The present invention provides enzymes which are uninhibited in tannin. In particular, tannin uninhibited, raw starch degrading ?-amylases are provided in accordance with the instant invention.
    Type: Application
    Filed: May 19, 2021
    Publication date: June 1, 2023
    Inventor: Jacob Flyvholm Cramer
  • Patent number: 11634673
    Abstract: The present disclosure provides methods, compositions, apparatuses and kits comprising two or more distant related glucoamylases in mashing having a synergistic effect on the released fermentable DPI sugar. Increased levels of DPI being primarily glucose is of high importance for high attenuation brewing applied for brewing low carb or light beers. In some embodiments, the present disclosure provides methods, apparatuses; compositions and kits for the use of two or more glucoamylases to increase the apparent specific activity in the mashing operation.
    Type: Grant
    Filed: September 19, 2018
    Date of Patent: April 25, 2023
    Assignee: DUPONT NUTRITION BIOSCIENCES APS
    Inventors: Jacob Flyvholm Cramer, Tove Bladt
  • Patent number: 11578316
    Abstract: Compositions and methods are provided comprising acetolactate decarboxylase (ALDC) enzyme variants having higher specific activity. Composition and method are provided where the ALDC variants are used in combination with metal ions to further increase stability and/or activity.
    Type: Grant
    Filed: September 12, 2017
    Date of Patent: February 14, 2023
    Assignee: DUPONT NUTRITION BIOSCIENCES APS
    Inventors: Jacob Flyvholm Cramer, Lene Kragh
  • Publication number: 20230002749
    Abstract: Described are polypeptides having glucoamylase activity, compositions comprising such polypeptides, and methods of using such polypeptides and compositions.
    Type: Application
    Filed: November 9, 2017
    Publication date: January 5, 2023
    Inventors: Jacob Flyvholm Cramer, Jing Ge, Marc Anton Bernhard Kolkman, Igor Nikolaev, Jayarama K. Shetty, Zhongmei Tang, Wilhelmus Antonius Van Der Kleij, Zhiyong Xie, Bo Zhang, Zhengzheng Zou
  • Publication number: 20220325307
    Abstract: A method for providing a low lactose milk-based product having GOS fiber is provided in which a milk substrate having lactose is treated with a transgalactosylating enzyme to provide GOS fiber and remaining lactose; deactivating the transgalactosylating enzyme; contacting the milk-based substrate having GOS fiber with a lactase to degrade the remaining lactose to provide the low lactose milk-based product having GOS fiber and deactivating the lactase. Also provided are enzymes and GOS fiber and lactose amounts and stability.
    Type: Application
    Filed: November 26, 2019
    Publication date: October 13, 2022
    Inventors: Jacob Flyvholm CRAMER, Tina Krogh JENSEN, Karina Hansen KJAER, Collette LENTZ
  • Publication number: 20220325211
    Abstract: Methods of using thermostable serine proteases are described herein.
    Type: Application
    Filed: January 20, 2022
    Publication date: October 13, 2022
    Inventors: Jacob Flyvholm Cramer, Marc Anton Bernhard Kolkman, Zhen Ma, Martijn Scheffers, Stepan Shipovskov, Marco Van Brussel-Zwijnen, Shukun Yu
  • Publication number: 20220259528
    Abstract: The present invention relates to methods of mashing 100% adjunct grists. More specifically, the instant disclosure provides methods and compositions wherein an alpha-amylase in combination with an maltogenic alpha amylase and/or glucoamylse to make a non-malt wort composed by adjunct raw materials.
    Type: Application
    Filed: October 21, 2019
    Publication date: August 18, 2022
    Inventors: Jacob Flyvholm CRAMER, Trove BLADT
  • Publication number: 20220159981
    Abstract: The present invention relates to polypeptides, specifically polypeptides having transgalactosylating activity and nucleic acids encoding these, and their uses in e.g. dairy product.
    Type: Application
    Filed: September 7, 2021
    Publication date: May 26, 2022
    Applicant: DuPont Nutrition Biosciences ApS
    Inventors: MORTEN KROG LARSEN, Jacob FLYVHOLM CRAMER
  • Publication number: 20220132878
    Abstract: This specification relates to a method for reducing the amount of lactose in a milk-based substrate containing lactose, wherein said method comprises contacting said substrate with an enzyme having neutral lactase activity at a temperature of more than about 50° C., and wherein said lactase reduces the amount of lactose in said substrate by at least about 70%.
    Type: Application
    Filed: February 27, 2020
    Publication date: May 5, 2022
    Inventors: Karina Hansen KJAER, Jacob Flyvholm CRAMER, Tina Krogh JENSEN, Tomoharu SATO, Cristina BONGIORNI
  • Publication number: 20210301279
    Abstract: Compositions and methods are provided comprising acetolactate decarboxylase (ALDC) enzyme variants having higher specific activity. Composition and method are provided where the ALDC variants are used in combination with metal ions to further increase stability and/or activity.
    Type: Application
    Filed: September 12, 2017
    Publication date: September 30, 2021
    Inventors: Jacob Flyvholm Cramer, Lene Bojsen Jensen
  • Publication number: 20210204555
    Abstract: The present invention relates to polypeptides, specifically polypeptides having transgalactosylating activity and nucleic acids encoding these, and their uses in e.g. dairy product.
    Type: Application
    Filed: November 4, 2019
    Publication date: July 8, 2021
    Inventors: MORTON KROG LARSEN, JACOB FLYVHOLM CRAMER
  • Publication number: 20200397031
    Abstract: A spray-dried composition comprising an enzyme which is a ?-galactosidase having transgalactosylating activity and a maltodextrin and/or sodium chloride.
    Type: Application
    Filed: May 26, 2020
    Publication date: December 24, 2020
    Inventors: MORTEN KROG LARSEN, Jens Damgaard, Bjarne Larsen, Jacob Flyvholm Cramer
  • Patent number: 10842163
    Abstract: A host cell capable of expressing a polypeptide having ?-galactosidase and/or transgalactosylating activity and which host cell is modified to be cellulase, mannanase and pectinase deficient.
    Type: Grant
    Filed: November 6, 2015
    Date of Patent: November 24, 2020
    Assignee: DUPONT NUTRITION BIOSCIENCES APS
    Inventors: Morten Krog Larsen, Jacob Flyvholm Cramer, Jeremy Labarge, Thomas Eisele, Karina Hansen Kjær
  • Publication number: 20200296980
    Abstract: A method of generating a saccharide, especially lactulose or lactosucrose, in the presence of a transgalactosylase enzyme, is described herein.
    Type: Application
    Filed: May 22, 2020
    Publication date: September 24, 2020
    Inventors: Thomas EISELE, Jacob Flyvholm CRAMER, Morten Krog LARSEN
  • Publication number: 20200263115
    Abstract: The present disclosure provides methods, compositions, apparatuses and kits comprising two or more distant related glucoamylases in mashing having a synergistic effect on the released fermentable DPI sugar. Increased levels of DPI being primarily glucose is of high importance for high attenuation brewing applied for brewing low carb or light beers. In some embodiments, the present disclosure provides methods, apparatuses; compositions and kits for the use of two or more glucoamylases to increase the apparent specific activity in the mashing operation.
    Type: Application
    Filed: September 19, 2018
    Publication date: August 20, 2020
    Inventors: Jacob Flyvholm Cramer, Trove Bladt
  • Patent number: 10683523
    Abstract: The present invention describes a process for in situ generation of stable GOS in different dairy products by the use of a transgalactosylating ?-galactosidase.
    Type: Grant
    Filed: December 11, 2014
    Date of Patent: June 16, 2020
    Assignee: DuPont Nutrition Biosciences ApS
    Inventors: Morten Krog Larsen, Jacob Flyvholm Cramer, Thomas Eisele