Patents by Inventor Jacob Hull Kristensen

Jacob Hull Kristensen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180267060
    Abstract: A method of bioassay for the quantification of peptide fragments elevated in lung diseases such as COPD, SCC, or IPF, comprising a neo-epitope formed at a cleavage site by cleavage in vivo of elastin by a proteinase by contacting a sample with an antibody having specific binding affinity for a the neo-epitope amino acid sequence and determining the level of binding, where the antibody binds one of the following terminal sequences: ...FGPGVV ...VPGLGV IKAPKL... and antibodies and immunoassay kits for use in such methods.
    Type: Application
    Filed: May 31, 2018
    Publication date: September 20, 2018
    Applicant: Nordic Bioscience A/S
    Inventors: Jacob Hull Kristensen, Diana Julie Oersnes-Leeming, Morten Darsdal
  • Patent number: 10001490
    Abstract: Provided is a method of bioassay for the quantification of peptide fragments elevated in lung diseases such as COPD, SCC, or IPF. The peptide fragments comprise a neo-epitope formed at a cleavage site by cleavage in vivo of elastin by a proteinase. In the method a sample is contacted with an antibody having specific binding affinity for the neo-epitope amino acid sequence and determining the level of binding is determined where the antibody binds one of the following terminal sequences: . . . FGPGVV, . . . VPGLGV or IKAPKL . . . . Also provided are antibodies and immunoassay kits for use in such methods.
    Type: Grant
    Filed: January 8, 2015
    Date of Patent: June 19, 2018
    Assignee: Nordic Bioscience A/S
    Inventors: Jacob Hull Kristensen, Diana Julie Oersnes-Leeming, Morten Karsdal
  • Publication number: 20160334416
    Abstract: Provided is a method of bioassay for the quantification of peptide fragments elevated in lung diseases such as COPD, SCC, or IPF. The peptide fragments comprise a neo-epitope formed at a cleavage site by cleavage in vivo of elastin by a proteinase. In the method a sample is contacted with an antibody having specific binding affinity for the neo-epitope amino acid sequence and determining the level of binding is determined where the antibody binds one of the following terminal sequences: . . . FGPGVV, . . . VPGLGV or IKAPKL . . . . Also provided are antibodies and immunoassay kits for use in such methods.
    Type: Application
    Filed: January 8, 2015
    Publication date: November 17, 2016
    Applicant: Nordic Bioscience A/S
    Inventors: Jacob Hull Kristensen, Diana Julie Oersnes-Leeming, Morten Karsdal