Patents by Inventor Jacob J. Plattner

Jacob J. Plattner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • OXABOROLE ESTERS AND USES THEREOF
    Publication number: 20230132298
    Abstract: The present invention provides oxaborole ester compounds and compositions thereof which are useful to treat diseases associated with parasites, such as Chagas Disease and African Animal Trypanosomosis.
    Type: Application
    Filed: December 22, 2022
    Publication date: April 27, 2023
    Inventors: Tsutomu AKAMA, David Scott CARTER, Jason S. HALLADAY, Robert T. JACOBS, Yang LIU, Jacob J. PLATTNER, Yong-Kang ZHANG, Michael John WITTY
  • Oxaborole esters and uses thereof
    Patent number: 11578087
    Abstract: The present invention provides oxaborole ester compounds and compositions thereof which are useful to treat diseases associated with parasites, such as Chagas Disease and African Animal Trypanosomosis.
    Type: Grant
    Filed: December 1, 2020
    Date of Patent: February 14, 2023
    Assignee: Anacor Pharmaceuticals, Inc.
    Inventors: Tsutomu Akama, David Scott Carter, Jason S. Halladay, Robert T. Jacobs, Yang Liu, Jacob J. Plattner, Yong-Kang Zhang, Michael John Witty
  • BORON CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS
    Publication number: 20230008130
    Abstract: Methods of treating anti-inflammatory conditions through the use of boron-containing small molecules are disclosed.
    Type: Application
    Filed: July 20, 2022
    Publication date: January 12, 2023
    Applicant: Anacor Pharmaceuticals, Inc.
    Inventors: Stephen J. Baker, Virginia Sanders, Tsutomu Akama, Carolyn Bellinger-Kawahara, Yvonne Freund, Kirk R. Maples, Jacob J. Plattner, Yong-Kang Zhang, Huchen Zhou, Vincent S. Hernandez
  • 4-substituted benzoxaborole compounds and uses thereof
    Patent number: 11214582
    Abstract: Substituted benzoxaboroles whose structure comprises Formula (III), wherein R3 is selected from —CH3, —CII2CII3, —CII2?CII2, —CII2CII2CII3, —CH(CH3)2, —CH2CH2?CH2, and cyclopropyl, R1 and R2 are each independently selected from H, —CH3, —CH2CH3, —CH2CH2CH3, and —CH(CH3)2; compositions containing such compounds, their use in therapy, including their use as anti-mycobacterial agents, for example in the treatment of a mycobacterial infection in a mammal, and methods for the preparation of such compounds, are provided.
    Type: Grant
    Filed: September 11, 2020
    Date of Patent: January 4, 2022
    Assignees: GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED, ANACOR PHARMACEUTICALS, INC.
    Inventors: Carlos Alemparte-Gallardo, Michael Richard Kevin (Dickon) Alley, David Barros-Aguirre, Ilaria Giordano, Vincent Hernandez, Xianfeng Li, Jacob J. Plattner
  • Boron-containing small molecules as antiprotozoal agents
    Patent number: 11161858
    Abstract: This invention provides, among other things, novel compounds useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.
    Type: Grant
    Filed: April 23, 2020
    Date of Patent: November 2, 2021
    Assignee: Anacor Pharmaceuticals, Inc.
    Inventors: Tsutomu Akama, Eric Easom, Yvonne Freund, Jacob J. Plattner, Jessica Sligar, Daitao Chen, Jennifer Freeman, Joe Perales
  • BORON-CONTAINING SMALL MOLECULES
    Publication number: 20210261574
    Abstract: Compounds, pharmaceutical formulations, and methods of treating bacterial infections are disclosed.
    Type: Application
    Filed: February 12, 2021
    Publication date: August 26, 2021
    Applicant: Bill & Melinda Gates Foundation
    Inventors: Xianfeng LI, Christopher S. LUNDE, Robert T. JACOBS, Vincent S. HERNANDEZ, Yi XIA, Jacob J. PLATTNER, Kathy Jingyuan CAO, Yong-Kang ZHANG, Matthew PERRY
  • Boron-containing small molecules
    Patent number: 11008345
    Abstract: This invention relates to, among other items, benzoxaborole compounds and their use for treating bacterial infections.
    Type: Grant
    Filed: July 30, 2019
    Date of Patent: May 18, 2021
    Assignee: Anacor Pharmaceuticals, Inc.
    Inventors: Vincent S. Hernandez, Charles Ding, Jacob J. Plattner, Michael Richard Kevin Alley, Fernando Rock, Suoming Zhang, Eric Easom, Xianfeng Li, Ding Zhou
  • OXABOROLE ESTERS AND USES THEREOF
    Publication number: 20210101916
    Abstract: The present invention provides oxaborole ester compounds and compositions thereof which are useful to treat diseases associated with parasites, such as Chagas Disease and African Animal Trypanosomosis.
    Type: Application
    Filed: December 1, 2020
    Publication date: April 8, 2021
    Inventors: Tsutomu AKAMA, David Scott CARTER, Jason S. HALLADAY, Robert T. JACOBS, Yang LIU, Jacob J. PLATTNER, Yong-Kang ZHANG, Michael John WITTY
  • BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS
    Publication number: 20210070779
    Abstract: Compounds, pharmaceutical formulations, and methods of treating anti-inflammatory conditions are disclosed.
    Type: Application
    Filed: October 8, 2020
    Publication date: March 11, 2021
    Inventors: Tsutomu Akama, Jacob J. Plattner
  • Boron-Containing Small Molecules
    Publication number: 20210070780
    Abstract: This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal infections. This invention is directed to compounds that are active against fungi and have properties that allow the compound, when placed in contact with a patient, to reach the particular part of the skin, nail, hair, claw or hoof infected by the fungus. In particular the present compounds have physiochemical properties that facilitate penetration of the nail plate.
    Type: Application
    Filed: November 16, 2020
    Publication date: March 11, 2021
    Applicant: Anacor Pharmaceuticals, Inc.
    Inventors: Stephen J. Baker, Tsutomu Akama, Carolyn Bellinger-Kawahara, Vincent S. Hernandez, Karin M. Hold, James J. Leyden, Kirk R. Maples, Jacob J. Plattner, Virginia Sanders, Yong-Kang Zhang
  • Tricyclic Benzoxaborole Compounds and Uses Thereof
    Publication number: 20210053999
    Abstract: Compounds of Formula II, wherein X is selected from chloro, fluoro, bromo and iodo, R1 and R2 are each independently selected from H, —CH3, —CH2CH3, —CH2CH2CH3, or —CH(CH3)2; compositions containing them, their use in therapy, including their use as anti-mycobacterial agents, for example in the treatment of a mycobacterial infection in a mammal, and methods for the preparation of such compounds, are provided.
    Type: Application
    Filed: November 4, 2020
    Publication date: February 25, 2021
    Inventors: Michael Richard Kevin Alley, Vincent S. Hernandez, Jacob J. Plattner, Xianfeng Li, David Barros-Aguirre, Ilaria Giordano
  • 4-Substituted Benzoxaborole Compounds and Uses Thereof
    Publication number: 20210053996
    Abstract: Substituted benzoxaboroles whose structure comprises Formula (III), wherein R3 is selected from —CH3, —CII2CII3, —CII2?CII2, —CII2CII2CII3, —CH(CH3)2, —CH2CH2?CH2, and cyclopropyl, R1 and R2 are each independently selected from H, —CH3, —CH2CH3, —CH2CH2CH3, and —CH(CH3)2; compositions containing such compounds, their use in therapy, including their use as anti-mycobacterial agents, for example in the treatment of a mycobacterial infection in a mammal, and methods for the preparation of such compounds, are provided.
    Type: Application
    Filed: September 11, 2020
    Publication date: February 25, 2021
    Inventors: Carlos Alemparte-Gallardo, Michael Richard Kevin (Dickon) Alley, David Barros-Aguirre, Ilaria Giordano, Vincent Hernandez, Xianfeng Li, Jacob J. Plattner
  • Boron-containing small molecules
    Patent number: 10919916
    Abstract: Compounds, pharmaceutical formulations, and methods of treating bacterial infections are disclosed.
    Type: Grant
    Filed: April 3, 2020
    Date of Patent: February 16, 2021
    Assignee: Bill & Melinda Gates Foundation
    Inventors: Xianfeng Li, Christopher S Lunde, Robert T Jacobs, Vincent S Hernandez, Yi Xia, Jacob J Plattner, Kathy Jingyuan Cao, Yong-Kang Zhang, Matthew Perry
  • BORON CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS
    Publication number: 20210000847
    Abstract: Methods of treating anti-inflammatory conditions through the use of boron-containing small molecules are disclosed.
    Type: Application
    Filed: August 27, 2020
    Publication date: January 7, 2021
    Applicant: Anacor Pharmaceuticals, Inc.
    Inventors: Stephen J. Baker, Virginia Sanders, Tsutomu Akama, Carolyn Bellinger-Kawahara, Yvonne Freund, Kirk R. Maples, Jacob J. Plattner, Yong-Kang Zhang, Huchen Zhou, Vincent S. Hernandez
  • Oxaborole esters and uses thereof
    Patent number: 10882872
    Abstract: The present invention provides oxaborole ester compounds and compositions thereof which are useful to treat diseases associated with parasites, such as Chagas Disease and African Animal Trypanosomosis.
    Type: Grant
    Filed: September 24, 2019
    Date of Patent: January 5, 2021
    Assignee: Anacor Pharmaceuticals, Inc.
    Inventors: Tsutomu Akama, David Scott Carter, Jason S. Halladay, Robert T. Jacobs, Yang Liu, Jacob J. Plattner, Yong-Kang Zhang, Michael John Witty
  • Tricyclic benzoxaborole compounds and uses thereof
    Patent number: 10858376
    Abstract: Compounds of Formula II, wherein X is selected from chloro, fluoro, bromo and iodo, R1 and R2 are each independently selected from H, —CH3, —CH2CH3, —CH2CH2CH3, or —CH(CH3)2; compositions containing them, their use in therapy, including their use as anti-mycobacterial agents, for example in the treatment of a mycobacterial infection in a mammal, and methods for the preparation of such compounds, are provided.
    Type: Grant
    Filed: November 26, 2019
    Date of Patent: December 8, 2020
    Assignees: GlaxoSmithKline Intellectual Property (No.2) Limited, Anacor Pharmaceuticals, Inc.
    Inventors: Michael Richard Kevin Alley, Vincent S. Hernandez, Jacob J. Plattner, Xianfeng Li, David Barros-Aguirre, Ilaria Giordano
  • 4-substituted benzoxaborole compounds and uses thereof
    Patent number: 10774096
    Abstract: Substituted benzoxaboroles whose structure comprises Formula (III), wherein R3 is selected from —CH3, —CH2CH3, —CH2?CH2, —CH2CH2CH3, —CH(CH3)2, —CH2CH2?CH2, and cyclopropyl, R1 and R2 are each independently selected from H, —CH3, —CH2CH3, —CH2CH2CH3, and —CH(CH3)2; compositions containing such compounds, their use in therapy, including their use as anti-mycobacterial agents, for example in the treatment of a mycobacterial infection in a mammal, and methods for the preparation of such compounds, are provided.
    Type: Grant
    Filed: February 12, 2016
    Date of Patent: September 15, 2020
    Assignees: GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED, ANACOR PHARMACEUTICALS, INC.
    Inventors: Carlos Alemparte-Gallardo, Michael Richard Kevin (Dickon) Alley, David Barros-Aguirre, Ilaria Giordano, Vincent Hernandez, Xianfeng Li, Jacob J. Plattner
  • BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS
    Publication number: 20200247828
    Abstract: This invention provides, among other things, novel compounds useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.
    Type: Application
    Filed: April 23, 2020
    Publication date: August 6, 2020
    Inventors: Tsutomu Akama, Eric Easom, Yvonne Freund, Jacob J. Plattner, Jessica Sligar, Daitao Chen, Jennifer Freeman, Joe Perales
  • BORON-CONTAINING SMALL MOLECULES
    Publication number: 20200247827
    Abstract: Compounds, pharmaceutical formulations, and methods of treating bacterial infections are disclosed.
    Type: Application
    Filed: April 3, 2020
    Publication date: August 6, 2020
    Applicant: Bill & Melinda Gates Foundation
    Inventors: Xianfeng LI, Christopher S LUNDE, Robert T JACOBS, Vincent S HERNANDEZ, Yi XIA, Jacob J PLATTNER, Kathy Jingyuan CAO, Yong-Kang ZHANG, Matthew PERRY
  • BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS
    Publication number: 20200207789
    Abstract: Compounds, pharmaceutical formulations, and methods of treating anti-inflammatory conditions are disclosed.
    Type: Application
    Filed: March 9, 2020
    Publication date: July 2, 2020
    Inventors: Tsutomu AKAMA, Jacob J. Plattner