Patents by Inventor Jacob M. Janey

Jacob M. Janey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMMOBILIZED TRANSAMINASES AND PROCESS FOR MAKING AND USING IMMOBILIZED TRANSAMINASE
    Publication number: 20140106413
    Abstract: The invention is directed to immobilized transaminases and methods of making and using them.
    Type: Application
    Filed: June 18, 2012
    Publication date: April 17, 2014
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Matthew D. Truppo, Jacob M. Janey, Gregory Hughes
  • PROCESS FOR PREPARING CHIRAL DIPEPTIDYL PEPTIDASE-IV INHIBITORS
    Publication number: 20140107346
    Abstract: A process for the preparation of pyrazolopyrolidines of structural formula I: and W is or P, wherein in P is an amine protecting group. These compounds are useful in the synthesis of dipeptidyl peptidase-IV inhibitors for the treatment of Type 2 diabetes. Also provided are useful intermediates obtained from the process.
    Type: Application
    Filed: June 25, 2012
    Publication date: April 17, 2014
    Applicants: Merck Sharp & Dohme Ltd., Merck Sharp & Dohme Corp.
    Inventors: Michael J. Zacuto, Robert F. Dunn, Aaron J. Moment, Jacob M. Janey, David Lieberman, Faye Sheen, Nadine Bremeyer, Jeremy Scott, Jeffrey T. Kuethe
  • Transaminase Biocatalysts
    Publication number: 20120329108
    Abstract: The present disclosure relates to polypeptides having transaminase activity, polynucleotides encoding the polypeptides, and methods of using the polypeptides.
    Type: Application
    Filed: September 5, 2012
    Publication date: December 27, 2012
    Applicant: CODEXIS, INC.
    Inventors: Christopher Savile, Emily Mundorff, Jeffrey C. Moore, Paul N. Devine, Jacob M. Janey
  • Transaminase biocatalysts
    Patent number: 8293507
    Abstract: The present disclosure relates to polypeptides having transaminase activity, polynucleotides encoding the polypeptides, and methods of using the polypeptides.
    Type: Grant
    Filed: February 26, 2010
    Date of Patent: October 23, 2012
    Assignee: Codexis, Inc.
    Inventors: Christopher Savile, Emily Mundorff, Jeffrey C. Moore, Paul N. Devine, Jacob M. Janey
  • TRANSAMINASE BIOCATALYSTS
    Publication number: 20100285541
    Abstract: The present disclosure relates to polypeptides having transaminase activity, polynucleotides encoding the polypeptides, and methods of using the polypeptides.
    Type: Application
    Filed: February 26, 2010
    Publication date: November 11, 2010
    Applicant: CODEXIS, INC.
    Inventors: Christopher Saville, Emily Mundorff, Jeffrey C. Moore, Paul N. Devine, Jacob M. Janey
  • PROCESS FOR MAKING GLUCOCORTICOID RECEPTOR LIGANDS
    Publication number: 20100228036
    Abstract: The invention encompasses a process for making 2-[1-phenyl-5-hydroxy-4alpha-methyl-hexahydrocyclopenta[f]indazol-5-yl]ethyl phenyl derivatives, which are glucocorticoid receptor ligands, useful for the treatment of inflammatory and immunological diseases.
    Type: Application
    Filed: October 20, 2008
    Publication date: September 9, 2010
    Inventors: Qinghao Chen, Shinji Fujimori, Jacob M. Janey, John Limanto, Rafik Naccache, Andrew F. Nolting, Zhigou J. Song, Neil Strotman, Lushi Tan, Mark Weisel