Patents by Inventor Jacob Myerson

Jacob Myerson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230001009
    Abstract: Provided herein are compositions comprising a nanoparticle and a D20 tag. The D20 tag comprises dibenzocyclooctyne (DBCO) covalently attached to a protein. Also provided are diagnostic and therapeutic methods utilizing the nanoparticle composition.
    Type: Application
    Filed: December 3, 2020
    Publication date: January 5, 2023
    Inventors: Jacob Myerson, Jacob Brenner, Vladimir Muzykantov, Landis R. Walsh, Priyal Patel
  • Patent number: 11123441
    Abstract: Compositions comprising a red blood cell (RBC) having non-toxically coupled thereto a nanoparticle having a low shear modulus or low Young's modulus of less than 10 MPa and containing a drug are provided. In one embodiment, the nanoparticles are optionally coated with protein. In another embodiment, the nanoparticle has no cell-specific targeting moiety or tissue-specific targeting moiety or organ-specific targeting moiety associated therewith. Methods of delivering selected drugs to target organs use these compositions both in vivo and ex vivo treatment of disease and for imaging.
    Type: Grant
    Filed: October 2, 2017
    Date of Patent: September 21, 2021
    Assignees: The Trustees of the University of Pennsylvania, The Regents of the University of California
    Inventors: Vladimir Muzykantov, Jacob Brenner, Jacob Myerson, Daniel Pan, Samir Suresh Mitragotri
  • Publication number: 20180243440
    Abstract: Compositions comprising a red blood cell (RBC) having non-toxically coupled thereto a nanoparticle having a low shear modulus or low Young's modulus of less than 10 MPa and containing a drug are provided. In one embodiment, the nanoparticles are optionally coated with protein. In another embodiment, the nanoparticle has no cell-specific targeting moiety or tissue-specific targeting moiety or organ-specific targeting moiety associated therewith. Methods of delivering selected drugs to target organs use these compositions both in vivo and ex vivo treatment of disease and for imaging.
    Type: Application
    Filed: October 2, 2017
    Publication date: August 30, 2018
    Inventors: Vladimir Muzykantov, Jacob Brenner, Jacob Myerson, Daniel Pan
  • Patent number: 9808500
    Abstract: The present invention encompasses an antithrombotic nanoparticle and use thereof.
    Type: Grant
    Filed: October 25, 2016
    Date of Patent: November 7, 2017
    Assignee: WASHINGTON UNIVERSITY
    Inventors: Samuel A. Wickline, Jacob Myerson, Rohun Palekar, Hua Pan
  • Patent number: 9764043
    Abstract: The present invention encompasses an antithrombotic nanoparticle.
    Type: Grant
    Filed: December 17, 2010
    Date of Patent: September 19, 2017
    Assignee: WASHINGTON UNIVERSITY
    Inventors: Jacob Myerson, Samuel A. Wickline
  • Publication number: 20170065669
    Abstract: The present invention encompasses an antithrombotic nanoparticle and use thereof.
    Type: Application
    Filed: October 25, 2016
    Publication date: March 9, 2017
    Inventors: Samuel A. Wickline, Jacob Myerson
  • Publication number: 20130064765
    Abstract: The present invention encompasses an antithrombotic nanoparticle.
    Type: Application
    Filed: December 17, 2010
    Publication date: March 14, 2013
    Applicant: THE WASHINGTON UNIVERSITY
    Inventors: Jacob Myerson, Samuel A. Wickline