Patents by Inventor Jacqueline E. Dawson

Jacqueline E. Dawson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Identification of a new ehrlichia species from a patient suffering from ehrlichiosis
    Patent number: 6541199
    Abstract: A new isolate of Ehrlichia species has been obtained from a patient suffering from ehrlichiosis. The new isolate has been found to be similar, but distinctly different from E. canis. A diagnostic kit and methods for diagnosing ehrlichiosis in humans and for screening drugs toxic to the new isolate have been described.
    Type: Grant
    Filed: April 16, 1998
    Date of Patent: April 1, 2003
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Jacqueline E. Dawson, Burt Anderson
  • Identification of a new ehrlichia species from a patient suffering from ehrlichiosis
    Patent number: 6524590
    Abstract: A new isolate of Ehrlichia species has been obtained from a patient suffering from ehrlichiosis. The new isolate has been found to be similar, but distinctly different from E. canis. A diagnostic kit and methods for diagnosing ehrlichiosis in humans and for screening drugs toxic to the new isolate have been described.
    Type: Grant
    Filed: January 26, 2000
    Date of Patent: February 25, 2003
    Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
    Inventors: Jacqueline E. Dawson, Burt Anderson
  • Identification of a new ehrlichia species from a patient suffering from ehrlichiosis
    Publication number: 20020192672
    Abstract: A new isolate of Ehrlichia species has been obtained from a patient suffering from ehrlichiosis. The new isolate has been found to be similar, but distinctly different from E. canis. A diagnostic kit and methods for diagnosing ehrlichiosis in humans and for screening drugs toxic to the new isolate have been described.
    Type: Application
    Filed: January 17, 2002
    Publication date: December 19, 2002
    Applicant: The Government, represented by the Secretary, Department of Health and Human Services
    Inventors: Jacqueline E. Dawson, Burt Anderson
  • Use of human immortalized endothelial cells to isolate and propagate Ehrlichia chaffeensis and Ehrlichia canis
    Patent number: 5989848
    Abstract: This invention provides a purified immortalized human endothelial cell infected with Ehrlichia chaffeensis or Ehrlichia canis. Also provided is a method of simultaneously screening a sample from a human subject for the presence of E. chaffeensis and Rickettsia rickettsii comprising contacting the sample with immortalized human endothelial cells under conditions which allow infection of the cells and detecting the presence of infection, the presence of infection indicating the presence of E. chaffeensis and/or R. rickettsii. The invention also provides a method of screening a sample from a human subject for the presence of E. chaffeensis comprising contacting the sample with endothelial cells under conditions which allow infection of the cells by E. chaffeensis and detecting the presence of infection by E. chaffeensis, the presence of infection by E. chaffeensis indicating the presence of E. chaffeensis in the sample. Finally, the invention provides a method of culturing E. chaffeensis or E.
    Type: Grant
    Filed: February 24, 1995
    Date of Patent: November 23, 1999
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventor: Jacqueline E. Dawson
  • Identification of a new Ehrlichia species from a patient suffering from Ehrlichiosis
    Patent number: 5789176
    Abstract: A new isolate of Ehrlichia species has been obtained from a patient suffering from ehrlichiosis. The new isolate has been found to be similar, but distinctly different from E. canis. A diagnostic kit and methods for diagnosing ehrlichiosis in humans and for screening drugs toxic to the new isolate have been described.
    Type: Grant
    Filed: October 3, 1997
    Date of Patent: August 4, 1998
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Jacqueline E. Dawson, Burt Anderson
  • Ehrlichia species from a patient suffering from ehrlichiosis
    Patent number: 5413931
    Abstract: A new isolate of Ehrlichia species has been obtained from a patient suffering from ehrlichiosis. The new isolate has been found to be similar, but distinctly different from E. canis. The new isolate is E. chaffeensis and is contained in a cell line of canine macrophage cells on deposit with the American Type Culture Collection under accession number CRL 10679. The new isolate must be contained in a cell line in order to remain viable but may be isolated from the cell line. However, the isolate will not remain viable outside of the cell line. A diagnostic kit and methods for diagnosing ehrlichiosis in humans and for screening drugs toxic to the new isolate have also been desclosed.
    Type: Grant
    Filed: November 5, 1993
    Date of Patent: May 9, 1995
    Assignee: United States of America
    Inventors: Jacqueline E. Dawson, Burt Anderson
  • Use of human immortalized endothelial cells to isolate and propagate Ehrlichia chaffeensis and Ehrlichia canis
    Patent number: 5401656
    Abstract: This invention provides a purified immortalized human endothelial cell infected with Ehrlichia chaffeensis or Ehrlichia canis. Also provided is a method of simultaneously screening a sample from a human subject for the presence of E. chaffeensis and Rickettsia rickettsii comprising contacting the sample with immortalized human endothelial cells under conditions which allow infection of the cells and detecting the presence of infection, the presence of infection indicating the presence of E. chaffeensis and/or R. rickettsii. The invention also provides a method of screening a sample from a human subject for the presence of E. chaffeensis comprising contacting the sample with endothelial cells under conditions which allow infection of the cells by E. chaffeensis and detecting the presence of infection by E. chaffeensis the presence of infection by E. chaffeensis indicating the presence of E. chaffeensis in the sample. Finally, the invention provides a method of culturing E. chaffeensis or E.
    Type: Grant
    Filed: October 30, 1992
    Date of Patent: March 28, 1995
    Assignee: United States of America
    Inventor: Jacqueline E. Dawson
  • Growing Ehrlichia species in a continuous cell line
    Patent number: 5192679
    Abstract: The present invention relates to a method of continually propagating Ehrlichia canis in a microphage-monocyte cell line referred to as DH82.
    Type: Grant
    Filed: May 3, 1990
    Date of Patent: March 9, 1993
    Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
    Inventors: Jacqueline E. Dawson, Yasuko Rikihisa