Abstract: Pharmaceutical compositions comprising compounds of the formula: R.sup.2 C{CH.sub.2 O(CH.sub.2).sub.n CO[NR.sup.3 CHR(CH.sub.2).sub.m CO].sub.q NOHR.sup.1 }.sub.3, wherein R is hydrogen, alkyl optionally substituted by OR.sup.5, SR.sup.5, NR.sup.5 R.sup.6, COR.sup.6, COOR.sup.6, CONR.sup.5 R.sup.6, --NHC(NR.sup.5 R.sup.6).dbd.NR.sup.7, aryl, aralkyl or heteroaryl; R.sup.1, R.sup.2 and R.sup.3 are independently selected from the group consisting of hydrogen, alkyl, aralkyl, aryl, COOR.sup.4, CONHR.sup.4 and CONR.sup.4 R.sup.4 ; R.sup.2 may additionally be alkyl substituted by alkoxy, alkenyloxy or by a group --O--(CH.sub.2).sub.p --COOX or --O--(CH.sub.2).sub.p --CONHX, wherein p is an integer from 1 to 10 and X is alkyl, aralkyl, aryl or heteroaryl; R.sup.4, R.sup.5 and R.sup.6 are hydrogen, alkyl, aralkyl, aryl or heteroaryl; n is 1 or 2, m is 0, 1 or 2 and q is 0 or 1, and when m is 0, the moiety --NR.sup.

Abstract: Vanadyl complexes of chelating dihydroxamate compounds suitable for oral treatment of diabetes are disclosed. The dipodal hydroxamate ion carriers effectively bind and transport vanadyl ions across lipid membranes and potentiate glucose metabolism. The complexes may be generated in vivo by administration of a vanadyl salt and the hydroxamate ion carrier.

Abstract: There are provided novel compounds useful as selective extractants of metal values from aqueous systems comprising a plurality of such ionic species. There is further provided a process for the production of the novel compounds. The invention also relates to a process of selective metal extraction by means of the novel compounds of the invention.

Abstract: There are provided novel compounds useful as selective extractants of metal values from aqueous systems comprising a plurality of such ionic species. There is further provided a process for the production of the novel compounds. The invention also relates to a process of selective metal extraction by means of the novel compounds of the invention.

Abstract: Ligand compounds useful as extractants of certain metals from solutions. Effective also as promoters of the growth of microorganisms.A process for the preparation of such hexadentate ligands and methods of selective extraction of transition and related metal ions from admixtures with other metals.

Abstract: There are provided novel enterobactin type compounds. There is provided a novel process for the production of enterobactin, and of novel enterobactin type compounds which process is based on the reaction of a serine derivative with a stannoxane of the [BU.sub.2 Sn(OCH.sub.2 CH.sub.2 O)] type. Enterobactin is a known compound of known utility. The novel derivatives are valuable as sequestering agents for iron and other transition metals, for the separation and analysis of same. They can be used as active ingredients in pharmaceutical compositions for the removal of such metals accumulated above an acceptable level in patients.