Patents by Inventor Jacques Decerprit

Jacques Decerprit has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7674803
    Abstract: The present invention relates to thiazolylpiperidine derivatives of the general formula (I): in which: A represents a radical chosen from the radicals a1 and a2 below: G represents a bond or a divalent radical chosen from the groups g1, g2 and g3 below: and R1, R2, R2?, R3, R4, R5, Y and Z are as defined in the description. Application of the compounds of the formula (I) to the treatment of hypertriglyceridaemia, hypercholesterolaemia and dyslipidaemia.
    Type: Grant
    Filed: June 2, 2004
    Date of Patent: March 9, 2010
    Assignee: Merck Patent GmbH
    Inventors: Philippe Guèdat, Francois Collonges, Hervé Dumas, Jean-Yves Ortholand, Jacques Decerprit, Jaxques Barbanton, Robert J. Foster, Peter Kane, Bernd Went
  • Publication number: 20070054939
    Abstract: The present invention relates to thiazolylpiperidine derivatives of the general formula (I): in which: A represents a radical chosen from the radicals a1 and a2 below: G represents a bond or a divalent radical chosen from the groups g1, g2 and g3 below: and R1, R2, R2?, R3, R4, R5, Y and Z are as defined in the description. Application of the compounds of the formula (I) to the treatment of hypertriglyceridaemia, hypercholesterolaemia and dyslipidaemia.
    Type: Application
    Filed: June 2, 2004
    Publication date: March 8, 2007
    Inventors: Philippe Guedat, Francois Collonges, Herve Dumas, Jean-Yves Ortholand, Jacques Decerprit, Jaxques Barbanton, Robert Foster, Peter Kane, Bernd Went
  • Publication number: 20060058372
    Abstract: The present invention relates to a compound of the formula (I): in which T, A, R, B Xi, Yi and n are as defined in Claim 1, and to the pharmaceutically usable derivatives, solvates and stereoisomers thereof, comprising a mixture thereof in all proportions, which can be used in the treatment of dyslipidaemia, and to pharmaceutical compositions comprising them.
    Type: Application
    Filed: October 1, 2003
    Publication date: March 16, 2006
    Inventors: Herve Dumas, Jacques Barbanton, Francois Collonges, Jacques Decerprit, Jean-Yves Ortholand, David Benzies, Stuart Cameron, Richard Foster, Stefan Guessregen, Peter Kane, Julia Lainton, Avril Robertson, Bernd Wendt, Mark Warne
  • Publication number: 20040063783
    Abstract: The present invention relates to a compound of formula (I) in which X, A, T, Y, G and R are as defined in Claim (1).
    Type: Application
    Filed: April 3, 2003
    Publication date: April 1, 2004
    Inventors: Claude Lardy, Jean-Yves Nioche, Lidia Caputo, Jacques Decerprit, Jean-Yves Ortholand, Didier Festal, Daniel Guerrier
  • Patent number: 5338849
    Abstract: These compounds correspond to the formula ##STR1## in which one of the groups X.sub.1 to X.sub.4 represents nitrogen and the others a CH radical,R.sub.1 and R.sub.2 represent H, halogen, alkyl, hydroxymethyl, alkyloxymethyl, dialkylaminoalkyl, dialkylaminoalkyloxymethyl, carboxyl, ethyl carboxylate, piperidino, alkenyl, cycloalkyl, cycloalkenyl, alkylthio, benzyl, phenyl, thiophene or pyridine, optionally substituted,R.sub.3 and R.sub.4 represent H, halogen, alkyl, cycloalkyl, alkoxy or alkylthio,R.sub.5 and R.sub.6 denote H, alkyl, alkenyl, cycloalkyl, cycloalkenyl, alkoxyalkyl or alkylthioalkyl, or together form alkylene or alkyleneoxyalkylene chains,R.sub.7 denotes H, alkyl or cycloalkyl; one of the radicals R.sub.5 to R.sub.7 can also denote optionally substituted phenyl or benzyl,R.sub.8 represents H, alkyl, cycloalkyl or optionally substituted phenyl or benzyl,R.sub.
    Type: Grant
    Filed: February 4, 1993
    Date of Patent: August 16, 1994
    Assignee: Lipha, Lyonnaise Industrielle Pharmaceutique
    Inventors: Didier Festal, Denis Descours, Jacques Decerprit
  • Patent number: 5219859
    Abstract: The invention relates to indole derivatives of formula 1, ##STR1## in which: R.sub.1 and R.sub.2 represent H, alkyl, alkenyl, cycloalkyl, N-alkylamino- or N,N-dialkylaminoalkyl, benzyl, pyridylmethyl or phenyl, optionally substituted,R.sub.3 and R.sub.4 represent H, halogen, alkyl, alkoxy, alkylthio, CF.sub.3, NO.sub.2, N-alkylamino or N,N-dialkylamino, benzyl or phenyl, optionally substituted,R.sub.5 represents H, alkyl, cycloalkyl or optionally substituted benzyl,R.sub.6 denotes an alkyl, phenyl or heterocyclic radical, optionally substituted,Z denotes the bivalent radicals --(CH.sub.2).sub.n --C(R.sub.7 R.sub.8)--(CH.sub.2).sub.p --, --CH=CH--C(R.sub.7 R.sub.8)-- in which n=0--2, p=0--2 and n+p.ltoreq.2, R.sub.7 and R.sub.
    Type: Grant
    Filed: March 20, 1992
    Date of Patent: June 15, 1993
    Assignee: Lipha, Lyonnaise Industrielle Pharmaceutique
    Inventors: Didier Festal, Denis Descours, Robert Bellemin, Jacques Decerprit
  • Patent number: 5183924
    Abstract: Derivatives of benzocycloalkenyldihydroxyalkanoic acids, inhibitors of HMG CoA reductase, antagonists of thromboxane A.sub.2 receptors and antifungals, denoted by the formula I ##STR1## in which X=CH.sub.2, O or S; R.sub.1 and R.sub.2, identical or different, =H, C.sub.1-3 alkyl or together form a --(CH.sub.2).sub.n -- chain (n=4,5) optionally substituted symmetrically by one or two C.sub.1-3 alkyl radicals.R.sub.3 and R.sub.4, identical or different, =H, CF.sub.3, halogen (Cl, F, Br), C.sub.1-5 N,N-dialkylamino, C.sub.1-4 alkyl, C.sub.1-5 -alkoxy, C.sub.1-3 alkylthio, or phenyl optionally substituted by at most substituents which may be identical or different and may denote C.sub.1-3 alkyl or C.sub.1-3 alkoxy radicals or halogens (F, Cl), it being understood that when one of R.sub.3 and R.sub.4 denotes the radicals: CF.sub.3, N,N-dialkylamino, C.sub.6 H.sub.5 or substituted phenyl, it is present at the vertices 3', R' or 5' according to formula 1 and the other denotes a hydrogen atom.R.sub.5 and R.sub.
    Type: Grant
    Filed: October 24, 1991
    Date of Patent: February 2, 1993
    Assignee: Lipha, Lyonnaise Industrielle Pharmaceutique
    Inventors: Didier Festal, Jean-Yves Nioche, Denis Descours, Robert Bellemin, Jacques Decerprit
  • Patent number: 5082859
    Abstract: Derivatives of benzocycloalkenyldihydroxyalkanoic acids, inhibitors of HMG CoA reductase, antagonists of thromoboxane A.sub.2 receptors and antifungals, denoted by the formula I ##STR1## in which X=CH.sub.2, O or S; R.sub.1 and R.sub.2, identical or different, =H, C.sub.1-3 alkyl or together from a --(CH.sub.2).sub.n -- chain (n=4,5) optionally substituted symmetrically by one or two C.sub.1-3 alkyl radicals.R.sub.3 and R.sub.4, identical or different, =H, CF.sub.3, halogen (Cl, F, Br), C.sub.1-5 N,N-dialkylamino, C.sub.1-4 alkyl, C.sub.1-5 -alkoxy, C.sub.1-3 alkylthio, or phenyl optionally substituted by at most two substitutents which may be identical or different and may denote C.sub.1-3 alkyl or C.sub.1-3 alkoxy radicals or halogens (F, Cl), it being understood that when one of R.sub.3 and R.sub.4 denotes the radicals: CF.sub.3, N,N-dialkylamino, C.sub.6 H.sub.5 or substituted phenyl, it is present at the vertices 3', 4'or 5' according to formula 1 and the other denotes a hydrogen atom.R.sub.5 and R.sub.
    Type: Grant
    Filed: January 24, 1990
    Date of Patent: January 21, 1992
    Assignee: Lipha, Lyonnaise Industrielle Pharmaceutique
    Inventors: Didier Festal, Jean-Yves Nioche, Denis Descours, Robert Bellemin, Jacques Decerprit