Abstract: Organic nitrates, processes for their preparation and their use in the treatment of vascular diseases and in particular in the treatment of angina.The said nitrates correspond to the following formula I:R--CO--(A).sub.n --Y--B (I)in which:R represents, in particular, a sulphur-containing radical and a sulphur-containing amino acid residue; A represents, in particular, a CH.sub.2 group or a substituted amino acid; n is 0 or 1 or greater than 1; Y represents an oxygen atom or an NH group and B represents, in particular, a 1,4:3,6-dianhydro hexitol mononitrate radical, an itol nitrate radical or an inositol radical.The said organic nitrates are prepared by reacting:I. either a thio acid of the type R--COOH, in which R has the same meaning as above, with a derivative of formula II: (A).sub.n --Y--B, in which A, Y, B and n have the same meaning as above,II. or a derivative of formula III: R--CO--(A).sub.

Abstract: New drugs comprising 2,3- or 3,4-diphenyl derivatives of .gamma.-nitrile-esters or the products of cyclization of the 2,3-diphenyl derivatives according to the formulae A, B and C are claimed.Process for cyclization of 2,3-diphenyl derivatives of .gamma.-nitrile-esters, new 2,3-diphenyl derivatives of .gamma.-nitrile-esters corresponding to the formulae I to VIII are claimed; new 3,4-diphenyl derivatives of the said esters coresponding to the formulae IX and X, and new 3,4-diphenylpiperidone derivatives corresponding to the specific formulae IX to XXVII are described.

Abstract: Halogen derivatives of 8-hydroxycarboxylic acids, which correspond to the formula ##STR1## (open form, in a basic medium) or to the formula ##STR2## (cyclized form, in an acid medium) in which formulae: X.sub.1 and X.sub.2 are halogen atoms, n.sub.1 and n.sub.2 are integers between 0 and 5, but, if n.sub.1 =0, n.sub.2 is different from 0, and vice versa, R is a hydrogen atom or an alkyl or aryl group, and Cation represents an ion originating from a base, or a metal ion, which is pharmaceutically compatible are suitable as antidepressants having a psychostimulant action.