Abstract: In general, systems for administering a dmg are provided. In an exemplary embodiment, a dmg administration system includes a dmg administration device configured to communicate with a computer system and at least one sensor configured to obtain sensor data and communicate the sensor data to the drug administration device. The dmg administration device is configured to utilize a first drug dosing scheme when a drug is delivered to a patient, determine a second drug dosing scheme for delivering a drug to the patient dependent on dosing data from the computer system and sensor data collected by the sensor during and/or after the delivery of the first drug according to the first drug dosing scheme, and utilize the second drug dosing scheme when the drug is delivered to the patient.

Abstract: In general, drug administration devices configured to communicate with networks and external devices are provided. In an exemplary embodiment, a drug administration device is configured to adjust an operational parameter of the drug administration device based on a data packet formed from drug administration data ancillary data received from networks and/or external devices. In another example embodiment, a drug administration device is configured to scan for and establish communications with at least one external device. In another example embodiment, a method includes assessing whether to update a control program on a drug administration device from a network or external device. In another example embodiment, a system includes a first drug administration device configured to communicate with a second drug administration device to optimize a drug treatment.

Abstract: In general, interconnection of drug administration systems is provided. In an exemplary embodiment, a drug administration device and a remotely located server can establish a unique key for wireless communication between the device and the server. The drug administration device can be configured to sense information relating to at least one of the device and a drug and can be configured to anonymize data indicative of the sensed information using the key stored in memory of the device. The drug administration device can also be configured to use the key in decrypting data received from the server.

Abstract: The present disclosure relates to drug administration. In an exemplary embodiment, a system can include a drug administration device configured to dispense a drug to a patient, a monitoring device configured to log a delivery event of drug delivery from the drug administration device into the patient, and a sensor configured to sense a patient parameter following delivery of the drug into the patient. In another exemplary embodiment, a drug administration device can include a drug holder configured to hold a drug, a dispensing mechanism configured to dispense the drug, and a sensor configured to sense a patient parameter, and the drug administration device can be configured to locally activate the drug at a target location in the patient. In another exemplary embodiment, methods, devices, and systems are provided to assess when operation of a drug dispensing mechanism is complete and to confirm whether drug administration was successful.

Abstract: Drug delivery systems and methods are provided for monitoring and/or tracking exposure of a drug to one or more conditions that can affect performance of the drug.

Abstract: A method of authenticating the legitimacy of a request for a resource from a resource provider by a user, including providing an authentication process in which a resource provider message is received and de-assembled, the integrity of the user request message is confirmed, a result indicator as to the legitimacy of the resource provider message is created by performing two or more authenticity checks, and an authentication result is sent.

Abstract: A method of authenticating the legitimacy of a request for a resource from a resource provider by a user, including providing an authentication process in which a resource provider message is received and de-assembled, the integrity of the user request message is confirmed, a result indicator as to the legitimacy of the resource provider message is created by performing two or more authenticity checks, and an authentication result is sent.

Abstract: A method of authenticating the legitimacy of a request for a resource from a resource provider by a user, including providing an authentication process in which a resource provider message is received and de-assembled, the integrity of the user request message is confirmed, a result indicator as to the legitimacy of the resource provider message is created by performing two or more authenticity checks, and an authentication result is sent.

Abstract: A method of authenticating the legitimacy of a request for a resource from a resource provider by a user, including providing an authentication process in which a resource provider message is received and de-assembled, the integrity of the user request message is confirmed, a result indicator as to the legitimacy of the resource provider message is created by performing two or more authenticity checks, and an authentication result is sent.

Abstract: The invention relates to the use of the peptide toxin APETx2 that blocks the ASIC3 cationic channels and that is derived from the Anthopleura elegantissima sea anemone, and to the use of the analogs and derivatives thereof as a drug, particularly as an analgesic pain associated with the activation of ASIC3 (Acid Sensing Ion Channel 3) channels, in particular pain occurring upon an inflammation and potentially upon any painful situation associated with tissue acidosis (ischemiae, fractures, hematoma, oedema, phlyctena, local infections, tissue lesions, ocular wounds, tumours, etc.).

Abstract: The invention relates to the use of the peptide toxin APETx2 that blocks the ASIC3 cationic channels and that is derived from the Anthopleura elegantissima sea anemone, and to the use of the analogs and derivatives thereof as a drug, particularly as an analgesic pain associated with the activation of ASIC3 (Acid Sensing Ion Channel 3) channels, in particular pain occurring upon an inflammation and potentially upon any painful situation associated with tissue acidosis (ischemiae, fractures, hematoma, oedema, phlyctena, local infections, tissue lesions, ocular wounds, tumours, etc.

Abstract: The present invention relates to new antibiotic macrolide compounds of the general formula I: with improved activity, to medicaments comprising such antibiotics, and to the use of such antibiotics for the treatment of infectious diseases, inflammatory diseases and human diseases or disorders which can be ameliorated by inhibition human phospdiesterases.

Abstract: This invention relates to a method, a device, a computer program and a computer program product for scan-rate conversion of an image signal, comprising interpolating between at least a first image area of a first image of said image signal and a second image area of a second image of said image signal to obtain at least one interpolated image area, extrapolating at least one image area of at least one image of said image signal to obtain at least one extrapolated image area, and mixing said at least one interpolated image area and said at least one extrapolated image area to obtain a mixed image area. Said step of mixing advantageously depends on the decision whether the image area that is to be interpolated and/or extrapolated is an occlusion area, and on the accuracy of at least one determined motion vector.

Abstract: Method of welding two hollow ceramic half-components containing an organic binder whereby each half-component is first loaded into a die, the jointing planes of the two half-components are then brought into contact by bringing together the two dies, working pressure is thereafter applied to one of the half-components in a direction perpendicular to the jointing planes and vibration is simultaneously applied to the other half-component in a direction parallel to the jointing planes to effect the welding of the two half-components by interpenetration. The two dies are then separated and the joined monobloc component is removed and sintered without altering the component's monolithic quality.

Abstract: An optical device and method for strain detection. The device is provided with at least one optical fiber arranged so as to form a network. A light emitting device is arranged at one end of the fiber and a receiver is arranged at the other end, enabling the generation of information relative to the light intensity transmitted by the fiber or fibers in the presence of strain, and a measurement corresponding to the strain.