Patents by Inventor Jacques Thilly
Jacques Thilly has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8720501Abstract: A hollow needle comprising a shaft having a distal portion suitable for passing through an elastomer closure of a container, said shaft extending in a longitudinal direction and having a central longitudinal axis, and having an internal longitudinal conduit therein for the flow of liquid and one or more orifices communicating between the conduit and the exterior of the needle, the distal portion of the shaft being provided with a pointed end that has a profile comprising a cutting edge in the form of two part cutting edges converging in the longitudinal direction to meet at the needle point, each part cutting edge extending in a straight line in a widthways direction across a plane including the central longitudinal axis, on both widthways sides of the cutting edge the pointed end having a profile which is a non-cutting surface, wherein the pointed end of the needle tapers from an outer surface of said distal portion toward the point of the needle, and the distance, measured in a further plane defined by saidType: GrantFiled: November 6, 2008Date of Patent: May 13, 2014Assignee: Aseptic Technologies S.A.Inventor: Jacques Thilly
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Patent number: 8574213Abstract: A process for preparing a lyophilized material, providing a container having a penetrable envelope and containing the material in a carrier liquid, whereby the penetrable region is penetrated with a penetrator which provides a conduit through the envelope, and the carrier liquid is evaporated out of the container via the conduit, after which the penetrator is withdrawn.Type: GrantFiled: July 11, 2012Date of Patent: November 5, 2013Assignee: Aseptic Technologies S.A.Inventors: Jacques Thilly, Christian Vandecasserie
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Publication number: 20120283689Abstract: A process for preparing a lyophilized material, providing a container having a penetrable envelope and containing the material in a carrier liquid, whereby the penetrable region is penetrated with a penetrator which provides a conduit through the envelope, and the carrier liquid is evaporated out of the container via the conduit, after which the penetrator is withdrawn.Type: ApplicationFiled: July 11, 2012Publication date: November 8, 2012Inventors: Jacques THILLY, Christian VANDECASSERIE
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Patent number: 8002130Abstract: A closure system for a vial comprising: an elastic closure part to engage the mouth opening, a clamp part to hold the closure part in a closing relationship with the mouth opening, the clamp part defining an upper aperture through which a region of the upper surface of the closure part is exposed when the clamp part is engaged with the vial, a cover part to engage the clamp part to cover the exposed region, the cover part engaging with the closure part to provide two or more concentric ring-shaped seals, at least part of the cover part being removable from the vial to allow access to the closure.Type: GrantFiled: May 15, 2006Date of Patent: August 23, 2011Assignee: Aseptic Technologies S.A.Inventor: Jacques Thilly
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Patent number: 7946437Abstract: A closure system for a pharmaceutical vial, comprising an elastomer closure part, a clamp part which holds the closure part in engagement with the mouth of the vial, and a cover part which engages with the clamp part. The interior of the closure part is profiled to minimize retention of residual liquid therein.Type: GrantFiled: August 15, 2003Date of Patent: May 24, 2011Assignee: Aseptic Technologies S.A.Inventors: Jacques Thilly, Christian Vandecasserie
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Patent number: 7851538Abstract: A novel elastomer material having an absorption coefficient for laser light of 0.5-2.5 mm?1, preferably being a base thermoplastic elastomer compounded with a colorant which comprises a Pantone 4597C pigment mixed with a carrier material. The elastomer is suited for use as a pharmaceutical vial closure which can be punctured by a filling needle and the puncture hole heat sealed by a focused laser.Type: GrantFiled: August 2, 2004Date of Patent: December 14, 2010Assignee: Aseptic Technologies S.A.Inventors: Jacques Thilly, Christian Vandecasserie
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Publication number: 20100294796Abstract: A hollow needle comprising a shaft having a distal portion suitable for passing through an elastomer closure of a container, said shaft extending in a longitudinal direction and having a central longitudinal axis, and having an internal longitudinal conduit therein for the flow of liquid and one or more orifices communicating between the conduit and the exterior of the needle, the distal portion of the shaft being provided with a pointed end that has a profile comprising a cutting edge in the form of two part cutting edges converging in the longitudinal direction to meet at the needle point, each part cutting edge extending in a straight line in a widthways direction across a plane including the central longitudinal axis, on both widthways sides of the cutting edge the pointed end having a profile which is a non-cutting surface, wherein the pointed end of the needle tapers from an outer surface of said distal portion toward the point of the needle, and the distance, measured in a further plane defined by saidType: ApplicationFiled: November 6, 2008Publication date: November 25, 2010Inventor: Jacques Thilly
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Patent number: 7832078Abstract: A process for making a medicinal vial in which a vial and a closure are moulded in parallel in respective vial and closure moulds, then the closure and vial are automatically assembled together, all in a sterile environment. An apparatus for performing this process is also provided. By the process and apparatus of the invention sealed vials with a sterile interior may be made.Type: GrantFiled: July 7, 2004Date of Patent: November 16, 2010Assignee: Aseptic Technologies S.A.Inventors: Jacques Thilly, Christian Vandecasserie
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Publication number: 20100016807Abstract: A syringe in which multiple sealing flanges are provided for sequential movement during use, to reduce sticking of the flange during use and the consequent jerking of the plunger stopper. In an embodiment longitudinally sequential flanges are linked by a flexible tube connection.Type: ApplicationFiled: April 11, 2007Publication date: January 21, 2010Inventor: Jacques Thilly
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Publication number: 20090306620Abstract: Medicinal vials are provided incorporating RFID's in a way which causes them to remain associated with the vial when the vial closure is opened. Several embodiments are disclosed. In a preferred embodiment an RFID is incorporated in the vial closure system.Type: ApplicationFiled: March 5, 2007Publication date: December 10, 2009Inventors: Jacques Thilly, Christian Vandecasseric
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Publication number: 20090158612Abstract: A process for preparing a lyophilized material, providing a container having a penetrable envelope and containing the material in a carrier liquid, whereby the penetrable region is penetrated with a penetrator which provides a conduit through the envelope, and the carrier liquid id evaporated out of the container via the conduit, after which the penetrator is withdrawn. Apparatus suitable for performing the process is also disclosed.Type: ApplicationFiled: October 25, 2005Publication date: June 25, 2009Inventors: Jacques Thilly, Christian Vandecasserie
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Publication number: 20090134114Abstract: A closure system for a vial comprising: an elastic closure part to engage the mouth opening, a clamp part to hold the closure part in a closing relationship with the mouth opening, the clamp part defining an upper aperture through which a region of the upper surface of the closure part is exposed when the clamp part is engaged with the vial, a cover part to engage the clamp part to cover the exposed region, the cover part engaging with the closure part to provide two or more concentric ring-shaped seals, at least part of the cover part being removable from the vial to allow access to the closure.Type: ApplicationFiled: May 15, 2006Publication date: May 28, 2009Inventor: Jacques Thilly
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Patent number: 7431352Abstract: A system for making a connection between the interior and exterior of a compartment, comprising a door opening through the compartment wall, a connector body which can engage with the wall, and having a connection port through it, and a removable cover on the connector body. The body is engaged with the door opening, and an inner door within the compartment engages and removes the cover. A preferred construction creates a single line of confidence seal. The system is particularly suited for sterile compartments.Type: GrantFiled: March 6, 2007Date of Patent: October 7, 2008Assignee: GlaxoSmithKline Biologicals s.a.Inventors: Jacques Thilly, Christian Vandecasserie
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Publication number: 20080196437Abstract: An apparatus for shell freezing a liquid content in a container, comprising an endless loop conveyor having a conveying length adapted to convey plural containers such as pharmaceutical vials, incorporating plural rollers to spin the containers as they are conveyed by the conveyor, and a return length, along at least part of the return length the rollers are immersed in a cooling liquid at a temperature below the freezing point of the liquid content of the containers, and along the conveying length the rollers are entirely above the surface of the cooling liquid. A preferred cooling liquid is liquid nitrogen, the evaporating vapour of which can be used to shield vials on the conveying length.Type: ApplicationFiled: May 9, 2005Publication date: August 21, 2008Applicant: GLAXOSMITHKLINEInventors: Jacques Thilly, Pierre-Jacques Van Roy
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Publication number: 20080140019Abstract: A process for filing a syringe in which a longitudinal tubular syringe barrel has a first end closed by a movable plunger and a connection suitable for an injection needle at its second end, this second end of the bore being closed by a penetrable closure, and the syringe is filled by passing a filling needle through the penetrable closure and filing the barrel with a liquid via the needle, then withdrawing the filing needle from the closure. Suitably a penetrator is attached to the second end of the barrel to penetrate and provide communication through the closure.Type: ApplicationFiled: November 30, 2005Publication date: June 12, 2008Inventors: Jacques Thilly, Christian Vandecasserie
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Patent number: 7365343Abstract: Apparatus for introducing a medicament into containers, especially vials, in which the containers are passed through an enclosure and exposed therein to a sterilising electron beam. The containers are then conveyed to a filling station situated outside the enclosure at which a wall part of the container is punctured with a filling needle and medicament introduced into the container via the needle then withdrawing the needle. Preferred apparatus also includes means for heat sealing the puncture site. A corresponding process is disclosed.Type: GrantFiled: February 19, 2004Date of Patent: April 29, 2008Assignee: GlaxoSmithKline Biologicals s.a.Inventors: Jacques Thilly, Christian Vandecasserie
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Publication number: 20080072992Abstract: A process for reducing the oxygen concentration in a container prior to filling the container with a liquid by passing a hollow filling needle through a puncturable part of the container wall, in which the empty container is enclosed within an envelope which is less permeable to oxygen than the container wall. The process is suitable for use with vials having a puncturable closure.Type: ApplicationFiled: September 25, 2007Publication date: March 27, 2008Inventors: Patrick Baleriaux, Jacques Thilly
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Publication number: 20080035218Abstract: Holding means for holding an article onto a conveyor system, particularly for holding pharmaceutical vials onto a conveyor system for performing a filling and sealing operation thereon. The holding means bears downwardly on the article. A conveyor system incorporating the holding means is also provided. In a further aspect an aerodynamically shrouded processing station for use with the conveyor is provided which minimizes disruption of a downward laminar flow of purified air.Type: ApplicationFiled: September 15, 2003Publication date: February 14, 2008Inventors: Jacques Thilly, Christian Vandecasserie
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Patent number: D561908Type: GrantFiled: December 11, 2006Date of Patent: February 12, 2008Assignee: Medical Instill Technologies, Inc.Inventors: Daniel Py, Norbert M. Assion, Julian V. Chan, Jacques Thilly, Christian Vandecasserie
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Patent number: D598124Type: GrantFiled: February 11, 2008Date of Patent: August 11, 2009Assignee: Medical Instill Technologies, Inc.Inventors: Daniel Py, Norbert M. Assion, Julian V. Chan, Jacques Thilly, Christian Vandecasserie