Patents by Inventor Jafar Golzarian

Jafar Golzarian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230347012
    Abstract: The present disclosure is generally directed to an embolic material in the form of a microparticle. The embolic material generally includes an alkene functionalized biopolymer. For instance, the embolic material may include a methacrylamide functionalized biopolymer. In some examples, the embolic material may further comprise a therapeutic agent, such as doxorubicin.
    Type: Application
    Filed: August 31, 2021
    Publication date: November 2, 2023
    Inventors: Chen Guo, Jafar Golzarian
  • Publication number: 20230248441
    Abstract: Techniques are disclosed for extended-reality (XR) visualization of a flexible medical tool. In one example, sensor(s), disposed near a distal portion of a flexible shaft of a medical tool configured for insertion into a patient, sense values indicative of a pose of the medical tool with respect to an EM field. A computing device adjusts, based on the sensed values, a relative alignment between the medical tool, an internal anatomy of the patient, and an exterior of the body of the patient. The computing device generates, based on the computed relative alignment between the medical tool, the internal anatomy, and the exterior of the body, XR content comprising a visual representation of the medical tool within the patients internal anatomy, and outputs the XR content for display to a user so as to simulate a current pose of the medical tool relative to the body of the patient.
    Type: Application
    Filed: June 29, 2021
    Publication date: August 10, 2023
    Inventors: Enio T. Perez Filho, Braden Eliason, Reza Talaie, Aaron Koenigsberg, Jafar Golzarian
  • Publication number: 20230095373
    Abstract: The present disclosure is generally directed to an embolic material which, in some embodiments, may be in the form of a microsphere or a plurality of microspheres. The embolic material generally comprises carboxymethyl chitosan (CCN) crosslinked with carboxymethyl cellulose (CMC). In some embodiments, the embolic material may further comprise a therapeutic agent, such as doxorubicin.
    Type: Application
    Filed: September 12, 2022
    Publication date: March 30, 2023
    Inventors: Jafar Golzarian, Lihui Weng
  • Patent number: 11439725
    Abstract: The present disclosure is generally directed to an embolic material which, in some embodiments, may be in the form of a microsphere or a plurality of microspheres. The embolic material generally comprises carboxymethyl chitosan (CCN) crosslinked with carboxymethyl cellulose (CMC). In some embodiments, the embolic material may further comprise a therapeutic agent, such as doxorubicin.
    Type: Grant
    Filed: November 30, 2018
    Date of Patent: September 13, 2022
    Assignee: Regents of the University of Minnesota
    Inventors: Jafar Golzarian, Lihui Weng
  • Patent number: 10869748
    Abstract: A vascular graft includes deformable sleeves that include an electrical component. The electrical component can be variable-resistance or piezoelectric, in embodiments, such that deformation of the sleeves due to pressure changes create or modify an electrical signal. A transponder can then transmit information relating to the pressure inside and outside of the vascular graft.
    Type: Grant
    Filed: May 3, 2017
    Date of Patent: December 22, 2020
    Assignee: Regents of the University of Minnesota
    Inventors: Michael Rosenberg, Sean Lester Moen, Jafar Golzarian
  • Publication number: 20190091368
    Abstract: The present disclosure is generally directed to an embolic material which, in some embodiments, may be in the form of a microsphere or a plurality of microspheres. The embolic material generally comprises carboxymethyl chitosan (CCN) crosslinked with carboxymethyl cellulose (CMC). In some embodiments, the embolic material may further comprise a therapeutic agent, such as doxorubicin.
    Type: Application
    Filed: November 30, 2018
    Publication date: March 28, 2019
    Inventors: Jafar Golzarian, Lihui Weng
  • Patent number: 10182979
    Abstract: The present disclosure describes a plurality of microspheres that include carboxymethyl chitosan (CCN) crosslinked with carboxymethyl cellulose (CMC). The microspheres are biocompatible, bioresorbable, and biodegradable. The microspheres may be used in personal care products, such as, for example, toothpaste, topical pain relief products, topical antibiotic products, skincare products such as anti-wrinkle products, eczema products, skin scrubs, acne cleansers, exfoliators, body washes, soaps, pre-shave creams, or the like.
    Type: Grant
    Filed: March 22, 2017
    Date of Patent: January 22, 2019
    Assignees: Regents of the University of Minnesota, EmboMedics, Inc.
    Inventors: Lihui Weng, Jafar Golzarian, Omid Souresrafil
  • Patent number: 10179187
    Abstract: The present disclosure is generally directed to an embolic material which, in some embodiments, may be in the form of a microsphere or a plurality of microspheres. The embolic material generally comprises carboxymethyl chitosan (CCN) crosslinked with carboxymethyl cellulose (CMC). In some embodiments, the embolic material may further comprise a therapeutic agent, such as doxorubicin.
    Type: Grant
    Filed: December 5, 2013
    Date of Patent: January 15, 2019
    Assignee: Regents of the University of Minnesota
    Inventors: Jafar Golzarian, Lihui Weng
  • Publication number: 20180078661
    Abstract: The present disclosure is generally directed to an embolic material which, in some examples, may be in the form of a microsphere or a plurality of microspheres. The embolic material may include carboxymethyl chitosan (CCN) crosslinked with partially oxidized carboxymethyl cellulose (OCMC) and an imaging agent such as at least one of an ethiodized oil, a radiopaque metal, or super paramagnetic iron oxide nanoparticles integrally contained within the microsphere.
    Type: Application
    Filed: September 19, 2017
    Publication date: March 22, 2018
    Inventors: Lihui Weng, Jafar Golzarian
  • Publication number: 20180078328
    Abstract: A nodule localization system includes a localization structure. The localization structure is arranged to extend from a nodule to a suture, and the entire coil can be located in the lung such that the suture extends through the pleural space. During normal respiration or other movement, the suture will move to be positioned mostly or entirely in the pleural space such that a surgeon can follow the suture to the coil and resect the nodule.
    Type: Application
    Filed: September 15, 2017
    Publication date: March 22, 2018
    Inventors: Michael Rosenberg, Sean Lester Moen, Jafar Golzarian
  • Publication number: 20170319326
    Abstract: A vascular graft includes deformable sleeves that include an electrical component. The electrical component can be variable-resistance or piezoelectric, in embodiments, such that deformation of the sleeves due to pressure changes create or modify an electrical signal. A transponder can then transmit information relating to the pressure inside and outside of the vascular graft.
    Type: Application
    Filed: May 3, 2017
    Publication date: November 9, 2017
    Inventors: Michael Rosenberg, Sean Lester Moen, Jafar Golzarian, Victor Barocas
  • Publication number: 20170273888
    Abstract: The present disclosure describes a plurality of microspheres that include carboxymethyl chitosan (CCN) crosslinked with carboxymethyl cellulose (CMC). The microspheres are biocompatible, bioresorbable, and biodegradable. The microspheres may be used in personal care products, such as, for example, toothpaste, topical pain relief products, topical antibiotic products, skincare products such as anti-wrinkle products, eczema products, skin scrubs, acne cleansers, exfoliators, body washes, soaps, pre-shave creams, or the like.
    Type: Application
    Filed: March 22, 2017
    Publication date: September 28, 2017
    Inventors: Lihui Weng, Jafar Golzarian, Omid Souresrafil
  • Publication number: 20160346521
    Abstract: A multi-lumen catheter defining a longitudinal axis includes an inflation lumen, a plug lumen, and a microcatheter lumen, each defined by the catheter and extending substantially parallel to the longitudinal axis. The inflation lumen defines an inlet aperture and an outlet aperture and is configured to provide a fluidic connection from the inlet aperture of the inflation lumen to a balloon. The plug lumen defines an inlet aperture and an outlet aperture and is configured to deliver a plug. The microcatheter lumen defines an inlet aperture and an outlet aperture and is configured to house a microcatheter.
    Type: Application
    Filed: May 23, 2016
    Publication date: December 1, 2016
    Inventors: Jafar Golzarian, Sean Lester Moen, Michael Rosenberg
  • Publication number: 20160243244
    Abstract: A system for providing a drug-eluting resorbable hydrogel for treating chronic pain, the system including carboxymethyl chitosan and oxidized carboxymethyl cellulose solutions, which together with one or more bioactive agents, can be mixed and delivered at the time of use in order to gel in situ within a joint space. Once delivered, the hydrogel can provide bioactive agents such as NSAIDs directly to the areas commonly associated with chronic pain, including to the spine, knee, shoulder, and elbow. The hydrogel is substantially non-inflammatory, and substantially biodegradable over time, to provide prolonged drug release.
    Type: Application
    Filed: February 19, 2016
    Publication date: August 25, 2016
    Inventors: Jafar Golzarian, Lihui Weng, Omid Souresrafil
  • Patent number: 8936795
    Abstract: A liquid embolic material may include a mixture of a first solution comprising between about 1.2% and about 2.5% weight per volume (w/v) carboxymethyl chitosan (CCN) in a first solvent and a second solution comprising between about 1.2% and about 2.5% w/v oxidized carboxymethyl cellulose (OCMC) in a second solvent. The liquid embolic material may be used to embolize a targeted embolization location by mixing the first solution and the second solution to form a liquid embolic material (or hydrogel precursor material), introducing the hydrogel precursor material to a targeted embolization location within a body of a patient, and allowing the CCN and the OCMC to react to form the hydrogel material and embolize the targeted embolization location.
    Type: Grant
    Filed: December 19, 2012
    Date of Patent: January 20, 2015
    Assignee: Regents of the University of Minnesota
    Inventors: Jafar Golzarian, Lihui Weng
  • Publication number: 20140171907
    Abstract: A liquid embolic material may include a mixture of a first solution comprising between about 1.2% and about 2.5% weight per volume (w/v) carboxymethyl chitosan (CCN) in a first solvent and a second solution comprising between about 1.2% and about 2.5% w/v oxidized carboxymethyl cellulose (OCMC) in a second solvent. The liquid embolic material may be used to embolize a targeted embolization location by mixing the first solution and the second solution to form a liquid embolic material (or hydrogel precursor material), introducing the hydrogel precursor material to a targeted embolization location within a body of a patient, and allowing the CCN and the OCMC to react to form the hydrogel material and embolize the targeted embolization location.
    Type: Application
    Filed: December 19, 2012
    Publication date: June 19, 2014
    Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Jafar Golzarian, Lihui Weng
  • Publication number: 20140099374
    Abstract: The present disclosure is generally directed to an embolic material which, in some embodiments, may be in the form of a microsphere or a plurality of microspheres. The embolic material generally comprises carboxymethyl chitosan (CCN) crosslinked with carboxymethyl cellulose (CMC). In some embodiments, the embolic material may further comprise a therapeutic agent, such as doxorubicin.
    Type: Application
    Filed: December 5, 2013
    Publication date: April 10, 2014
    Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Jafar Golzarian, Lihui Weng
  • Patent number: 8617132
    Abstract: The present disclosure is generally directed to an embolic material which, in some embodiments, may be in the form of a microsphere or a plurality of microspheres. The embolic material generally comprises carboxymethyl chitosan (CCN) crosslinked with carboxymethyl cellulose (CMC). In some embodiments, the embolic material may further comprise a therapeutic agent, such as doxorubicin.
    Type: Grant
    Filed: October 6, 2010
    Date of Patent: December 31, 2013
    Assignee: Regents of the University of Minnesota
    Inventors: Jafar Golzarian, Lihui Weng
  • Publication number: 20110082427
    Abstract: The present disclosure is generally directed to an embolic material which, in some embodiments, may be in the form of a microsphere or a plurality of microspheres. The embolic material generally comprises carboxymethyl chitosan (CCN) crosslinked with carboxymethyl cellulose (CMC). In some embodiments, the embolic material may further comprise a therapeutic agent, such as doxorubicin.
    Type: Application
    Filed: October 6, 2010
    Publication date: April 7, 2011
    Applicant: Regents of the University of Minnesota
    Inventors: Jafar Golzarian, Lihui Weng