Patents by Inventor Jagapathi Raju Srivatsavayi

Jagapathi Raju Srivatsavayi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparation of 4-fluoro-?-[2methyl-l-oxopropyl]-?-oxo—N—?-diphenylbenzene butane amide
    Patent number: 8946479
    Abstract: A process for preparation of 4-fluoro-?-[2-methyl-1-oxopropyl]-?-oxo-N-?-diphenylbenzene butane amide also known as a diketone intermediate of atorvastatin, completely devoid of impurities 3,4-difluoro-?-[2-methyl-1-oxopropyl]-?-oxo-n-?-diphenylbenzene butane amide; methyl, 2{-2[-(4-fluorophenyl)-2-oxo-1-phenylethyl)]}-4-methyl-3-oxo pentanoate; 1,4-bis(4-fluorophenyl)-2,3-diphenylbutane-1,4-dione, 1-(4-fluorophenyl)-2-phenyl ethanone; 1-(4-fluorophenyl)-2-phenyl ethanone and containing about 0.05% or less of 2-methyl-1-oxopropyl]-?-oxo-N-?-diphenylbenzene butane amide. In that process the said diketone intermediate of formula 1 is obtained by maintaining temperature ?25° C. to 50° C. during Friedel-Crafts acylation, in situ halogenation of formula II in presence of a solvent and nucleophilic substitution from a compound of formula III with formula IV in presence of a base.
    Type: Grant
    Filed: October 13, 2011
    Date of Patent: February 3, 2015
    Assignee: Vijayasri Organics Limited
    Inventors: Jagapathi Raju Srivatsavayi, Sairam Pothukuchi, Srinivasa Sastry Rani, Mallikarjuna Rao Chikka, Chiranjeevi Cheekati, Mallikarjuna Rao Gutti, Trimurthulu Singavarapu, Venkat Reddy Thimmaipally, Venkateswara Rao Tadanki
  • PROCESS FOR PREPARATION OF 4-FLUORO-alpha-[2METHYL-L-OXOPROPYL]-gamma-OXO-N-beta-DIPHENYLBENZENE BUTANE AMIDE
    Publication number: 20130184493
    Abstract: A process for preparation of 4-fluoro-?-[2-methyl-1-oxopropyl]-?-oxo-N-?-diphenylbenzene butane amide also known as a diketone intermediate of atorvastatin, completely devoid of impurities 3,4-difluoro-?-[2-methyl-1-oxopropyl]-?-oxo-n-?-diphenylbenzene butane amide; methyl, 2{-2[-(4-fluorophenyl)-2-oxo-1-phenylethyl)]}-4-methyl-3-oxo pentanoate; 1,4-bis(4-fluorophenyl)-2,3-diphenylbutane-1,4-dione, 1-(4-fluorophenyl)-2-phenyl ethanone; 1-(4-fluorophenyl)-2-phenyl ethanone and containing about 0.05% or less of 2-methyl-1-oxopropyl]-?-oxo-N-?-diphenylbenzene butane amide. In that process the said diketone intermediate of formula 1 is obtained by maintaining temperature ?25° C. to 50° C. during Friedel-Crafts acylation, in situ halogenation of formula II in presence of a solvent and nucleophilic substitution from a compound of formula III with formula IV in presence of a base.
    Type: Application
    Filed: October 13, 2011
    Publication date: July 18, 2013
    Applicant: VIJAYASRI ORGANICS LIMITED
    Inventors: Jagapathi Raju Srivatsavayi, Sairam Pothukuchi, Srinivasa Sastry Rani, Mallikarjuna Rao Chikka, Chiranjeevi Cheekati, Mallikarjuna Rao Gutti, Trimurthulu Singavarapu, Venkat Reddy Thimmaipally, Venkateswara Rao Tadanki