Patents by Inventor Jakob Skjold-Joergensen

Jakob Skjold-Joergensen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10870838
    Abstract: The present invention relates to a method for generating a preparation of a lipase variant of a parent lipase comprising a step of altering one or more nucleotides in a polynucleotide encoding the parent lipase, wherein the alteration provides at least one disulfide bond and a hydrolytic activity of said lipase variant which is reduced as compared with the hydrolytic activity of the parent lipase. The invention also relates to a polynucleotide encoding the lipase variant, the lipase variant and its use.
    Type: Grant
    Filed: November 30, 2016
    Date of Patent: December 22, 2020
    Assignee: NOVOZYMES A/S
    Inventors: Lone Baunsgaard, Allan Svendsen, Kim Borch, Rakhi Saikia, Jakob Skjold-Jørgensen
  • Patent number: 10457921
    Abstract: The present invention relates to a variant of a parent lipase, wherein said variant has at least 60% but less than 100% sequence identity with SEQ ID NO: 2, has lipase activity, comprises a substitution at a position corresponding to position 92 and/or 96; and remains unaltered at the positions corresponding to positions 231, 233 and 254 of SEQ ID NO: 2. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Grant
    Filed: December 1, 2015
    Date of Patent: October 29, 2019
    Assignee: Novozymes A/S
    Inventors: Allan Svendsen, Jesper Vind, Lone Baunsgaard, Jakob Skjold-Joergensen, Vikram Kjoeller Bhatia, Lars Henrik Oestergaard
  • Publication number: 20180340159
    Abstract: The present invention relates to a method for generating a preparation of a lipase variant of a parent lipase comprising a step of altering one or more nucleotides in a polynucleotide encoding the parent lipase, wherein the alteration provides at least one disulfide bond and a hydrolytic activity of said lipase variant which is reduced as compared with the hydrolytic activity of the parent lipase. The invention also relates to a polynucleotide encoding the lipase variant, the lipase variant and its use.
    Type: Application
    Filed: November 30, 2016
    Publication date: November 29, 2018
    Applicant: NOVOZYMES A/S
    Inventors: Lone Baunsgaard, Allan Svendsen, Kim Borch, Rakhi Saikia, Jakob Skjold-Jørgensen
  • Patent number: 9909109
    Abstract: The present invention relates to isolated lipase variants, comprising a substitution at one or more positions corresponding to positions I86D,E,N,Q, E87C, I90D,E,Q, and N92D,E,Q of the mature polypeptide of SEQ ID NO: 2, wherein the variant has lipase activity. In some embodiments the present invention relates to isolated polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; methods of producing the variants; and compositions comprising the variants. The present invention also relates to methods of obtaining lipase variants; methods of cleaning; and use of lipase variants for cleaning.
    Type: Grant
    Filed: March 22, 2013
    Date of Patent: March 6, 2018
    Assignee: NOVOZYMES A/S
    Inventors: Jakob Skjold-Joergensen, Jesper Vind, Allan Svendsen
  • Publication number: 20170314001
    Abstract: The present invention relates to a variant of a parent lipase, wherein said variant has at least 60% but less than 100% sequence identity with SEQ ID NO: 2, has lipase activity, comprises a substitution at a position corresponding to position 92 and/or 96; and remains unaltered at the positions corresponding to positions 231, 233 and 254 of SEQ ID NO:2. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: December 1, 2015
    Publication date: November 2, 2017
    Applicant: Novozymes A/S
    Inventors: Allan Svendsen, Jesper Vind, Lone Baunsgaard, Jakob Skjold-Joergensen, Vikram Kjoeller Bhatia, Lars Henrik Oestergaard
  • Publication number: 20150031111
    Abstract: The present invention relates to isolated lipase variants, comprising a substitution at one or more positions corresponding to positions I86D,E,N,Q, E87C, I90D,E,Q, and N92D,E,Q of the mature polypeptide of SEQ ID NO: 2, wherein the variant has lipase activity. In some embodiments the present invention relates to isolated polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; methods of producing the variants; and compositions comprising the variants. The present invention also relates to methods of obtaining lipase variants; methods of cleaning; and use of lipase variants for cleaning.
    Type: Application
    Filed: March 22, 2013
    Publication date: January 29, 2015
    Inventors: Jakob Skjold-Joergensen, Jesper Vind, Allan Svendsen