Abstract: The invention relates to compounds of formula (I), their method of synthesis as well as their use to treat neurodegenerative disorders.

Abstract: The invention relates to a tablet or capsule containing a plant extract, to assist in the treatment or prevention of disorders or diseases. The tablet or capsule includes bioconverted products provided by fermenting Withania Somnifera extract, Emblica officinalis extract, and Bacopa monnieri extract.

Abstract: The invention relates to compounds of formula (I), their method of synthesis as well as their use to treat neurodegenerative disorders.

Abstract: Compounds for treating neurodegenerative disorders The invention relates to compounds of formula (I), their method of synthesis as well as their use to treat neurodegenerative disorders.

Abstract: The invention relates to compounds of formula (I), their method of synthesis as well as their use to treat neurodegenerative disorders.

Abstract: The invention relates to the use of a composition from a plant extract of Withania somnifera, to treat or prevent amyloid-related diseases, including Alzheimer disease.

Abstract: The invention relates to a composition containing a Withania somnifera extract, obtained by fermentation by incubating the Withania somnifera extract with a filamentous fungus of the Beauveria genus. The composition can be used to treat or prevent ?-synucleinopathies in a subject.

Abstract: The invention relates to a tablet or capsule containing a plant extract, to assist in the treatment or prevention of disorders or diseases. The tablet or capsule includes bioconverted products provided by fermenting Withania Somnifera extract, Emblica officinalis extract, and Bacopa monnieri extract.

Abstract: The invention relates to a compound of general formula (I) wherein: R1 is a hydrogen atom or a C1 to C4 alkyl radical; R2 is a C1 to C4 hydroxyl or alkoxyl radical; and R3 and R4 are independently a hydrogen atom or a C1 à C4 alkyl radical; and the enantiomers and mixtures of enantiomers thereof, especially in a racemic form.

Abstract: The invention relates to a compound of general formula (I) wherein: R1 is a hydrogen atom or a C1 to C4 alkyl radical; R2 is a C1 to C4 hydroxyl or alkoxyl radical; and R3 and R4 are independently a hydrogen atom or a C1 à C4 alkyl radical; and the enantiomers and mixtures of enantiomers thereof, especially in a racemic form.

Abstract: This invention relates to a device intended for the culture of cells or micro-organisms, characterised by the fact that it comprises a chamber (100) composed of a tank (110) and a lid (150), adapted so that when in the closed state, it defines a sealed volume under a controlled pressure, and an assembly (200) designed to be placed inside the chamber (100), while being removable from it when the lid (150) is opened, said assembly comprising (200) a support frame (210) and a plurality of plates (250) carried by the support frame (210), the chamber (100) also comprising means designed to successively sterilise its content, for seeding a culture medium placed in the trays (250) and a means for controlling the atmosphere in the chamber (100), to enable the culture of cells or micro-organisms.

Abstract: This invention relates to a device intended for the culture of cells or micro-organisms, characterised by the fact that it comprises a chamber (100) composed of a tank (110) and a lid (150), adapted so that when in the closed state, it defines a sealed volume under a controlled pressure, and an assembly (200) designed to be placed inside the chamber (100), while being removable from it when the lid (150) is opened, said assembly comprising (200) a support frame (210) and a plurality of plates (250) carried by the support frame (210), the chamber (100) also comprising means designed to successively sterilise its content, for seeding a culture medium placed in the trays (250) and a means for controlling the atmosphere in the chamber (100), to enable the culture of cells or micro-organisms.

Abstract: The invention concerns a method for preparing a-amino acids of general formula (2S-1) wherein: the group R1 represents a hydrogen atom, a group protecting the amino group or a group of formula —COOR2 wherein the group R2 represents a C1-C6 alkyl group, an aryl or aralkyl group. The invention also concerns a-amino acids of general formula (2S-1) wherein the group R1 represents a group protecting the amino group or a group of formula —COOR2 wherein the group R2 represents a C1-C6 alkyl group, an aryl or aralkyl group and their use as medicine.

Abstract: The invention concerns a method for preparing a-amino acids of general formula (2S-1) wherein: the group R1 represents a hydrogen atom, a group protecting the amino group or a group of formula —COOR2 wherein the group R2 represents a C1-C6 alkyl group, an aryl or aralkyl group. The invention also concerns a-amino acids of general formula (2S-1) wherein the group R1 represents a group protecting the amino group or a group of formula —COOR2 wherein the group R2 represents a C1-C6 alkyl group, an aryl or aralkyl group and their use as medicine.

Abstract: The invention relates to a cosmetic composition for topical application containing, in a cosmetically acceptable carrier, an effective quantity of (2S,3R,4S)-4-hydroxyisoleucine and the use of such a composition for combating the natural signs of ageing of the skin and of the scalp.

Abstract: The invention concerns a method for preparing a-amino acids of general formula (2S-1) wherein: the group R1 represents a hydrogen atom, a group protecting the amino group or a group of formula —COOR2 wherein the group R2 represents a C1-C6 alkyl group, an aryl or aralkyl group. The invention also concerns a-amino acids of general formula (2S-1) wherein the group R1 represents a group protecting the amino group or a group of formula —COOR2 wherein the group R2 represents a C1-C6 alkyl group, an aryl or aralkyl group and their use as medicine.

Abstract: This invention relates to a method for the removal of a nitrogen containing heterocyclic or aromatic compound, comprising at least one nitro group, in an effluent by the conversion of said, at least one nitro group into an amine group by means of a reducing agent. The reducing agent can be hydrogen in the presence of Pd/C or a micro-organism. This invention also relates to a method for the synthesis of 5-amino-1,2,4-triazole-3-one from 5-nitro-1,2,4-triazole-3-one by said method of conversion, that allows one to achieve synthesis yields greater than 80%. This invention also relates to a colony of the type Bacillus licheniformis capable of converting one or more nitro groups of nitrogen containing heterocyclic compounds into one or more amine groups. This colony has been filed in the CNCM, held by the Pasteur Institute, under the number I-1915.

Abstract: The invention relates to an isolated Penicillium strain capable of eliminating a nitroaromatic compound by mineralization and a microbiological method for eliminating a nitroaromatic compound present in a solution or in a soil.