Abstract: The present invention relates to recombinant cells and microorganisms of the phylum Labyrinthulomycota and their use in heterologous protein production. Novel promoter, terminator, and signal sequences for efficient production and, optionally, secretion of polypeptides from recombinant host cells and microorganisms are also encompassed by the present invention.

Abstract: This disclosure concerns a novel modular docosahexaenoic acid (DHA) synthase and recombinant host organisms genetically modified with such synthase and one or more accessory proteins that allow for and/or improve the production of PUFAs in the host organism. The disclosure also concerns methods of making and using such organisms as well as products obtained from such organisms.

Abstract: The present invention relates to the field of molecular biology and cell biology. More specifically, the present invention trelates to a CRISPR-Cas system for a Labyrinthulomycetes host cell.

Abstract: Systems, computer-implemented methods, and non-transitory computer readable media are provided for sharing medical data. The disclosed systems may be configured to create a first workgroup having a first knowledgebase. This first knowledgebase may be federated with a common knowledgebase, and with a second knowledgebase of a second workgroup. At least one of the first knowledgebase, common knowledgebase, and second knowledgebase may be configured to store data items comprising associations, signs, and evidence. The signs may comprise measurements and contexts, and the associations may describe the relationships between the measurements and contexts. The evidence may support these associations. The disclosed systems may be configured to receive a request from a user in the first workgroup, retrieve matching data items, and optionally then output to the user at least some of the retrieved matching data items. The request may comprise at least one of a first association and a first measurement.

Abstract: The present invention relates to recombinant microalgal cells and their use in heterologous protein production, methods of production of heterologous polypeptides in microalgal extracellular bodies, microalgal extracellular bodies comprising heterologous polypeptides, and compositions comprising the same.

Abstract: The present invention discloses improvements to mechanical and electro-mechanical force simulators for aircraft pilot controllers, and particularly foot-actuated controllers. In particular, the invention replaces conventional foot-actuated, pilot controller systems—namely, those that employ multiple, discrete, motion control subsystems to control the various force simulation and trim functions used in modern aircraft to assist pilot control of a given axis of flight—with a single motion control system. The invention accomplishes this in part by eliminating the force-feel spring used in conventional, federated, foot-actuated, motor-coupled pilot controllers.

Abstract: Water tap (2) or water valve assembly is provided which has biometric recognition means (20) provided on or associated with the same. The biometric recognition means (20) are arranged such that operation of the water tap (2) or water valve assembly and/or operation of one or more functions of the water tap (2) or water valve assembly takes place only upon recognition or a positive match of one or more biometric features of a user.

Abstract: A method of improving the photoluminescence of silicon nanoparticles is provided along with a description of the silicon nanoparticle compositions prepared therefrom. The method generally comprises exposing a composition comprising silicon nanoparticles having a mean particle diameter not greater than 5 nm and a fluid to a non-ambient condition selected from (i) elevated temperature, (ii) elevated humidity, (iii) elevated pressure exerted by an oxygen-containing gas, (iv) a hydrogen plasma, (v) hydrogen gas, (vi) ultraviolet radiation, and (vii) and a combination of at least two of (i)-(vi). Optionally, the silicon nanoparticles may be prepared by a gas phase reaction. The exposure of the silicon nanoparticle compositions to the non-ambient condition results in improved photoluminescence. In particular, the exposed nanoparticles exhibit increased maximum emission intensity and luminescent quantum efficiency.

Abstract: The present invention relates to recombinant cells and microorganisms of the phylum Labyrinthulomycota and their use in heterologous protein production. Novel promoter, terminator, and signal sequences for efficient production and, optionally, secretion of polypeptides from recombinant host cells and microorganisms are also encompassed by the present invention.

Abstract: The present invention provides biological oils and methods and uses thereof. The biological oils are preferably produced by heterotrophic fermentation of one or more microorganisms using cellulose-containing feedstock as a main source of carbon. The present invention also provides methods of producing lipid-based biofuels and food, nutritional, and pharmaceutical products using the biological oils.

Abstract: The present invention provides biological oils and methods and uses thereof. The biological oils are preferably produced by heterotrophic fermentation of one or more microorganisms using cellulose-containing feedstock as a main source of carbon. The present invention also provides methods of producing lipid-based biofuels and food, nutritional, and pharmaceutical products using the biological oils.

Abstract: A crane boom has three telescoping sections which move consistently in a sequential pattern between extended and retracted positions. When extending, the outer section moves first, followed by the middle section. When retracting, the middle section moves first, followed by the outer section. A pair of hydraulic actuators with a series of valves control the extension and retraction of the outer and middle boom sections.

Abstract: A system for displaying a product is disclosed. The system includes a wall having a recess therein and a display structure that defines the recess. The display structure extends through a front surface of the wall and includes a frame having a top panel, a bottom panel, and two side panels. The top and bottom panels are longer than the side panels. The system further includes a plurality of modular display units disposed within the display structure. Each modular display unit extends from the bottom panel to the top panel. At least a first one of the modular display units includes a frame open to a front exterior of the display structure and at least a second one of the modular display units is not open to the front exterior of the display structure. The system further includes a plurality of display elements disposed within the plurality of display units.

Abstract: This disclosure concerns a novel modular docosahexaenoic acid (DHA) synthase and recombinant host organisms genetically modified with such synthase and one or more accessory proteins that allow for and/or improve the production of PUFAs in the host organism. The disclosure also concerns methods of making and using such organisms as well as products obtained from such organisms.

Abstract: A system for displaying a product is disclosed. The system includes a wall having a recess therein and a display structure that defines the recess. The display structure extends through a front surface of the wall and includes a frame having a top panel, a bottom panel, and two side panels. The top and bottom panels are longer than the side panels. The system further includes a plurality of modular display units disposed within the display structure. Each modular display unit extends from the bottom panel to the top panel. At least a first one of the modular display units includes a frame open to a front exterior of the display structure and at least a second one of the modular display units is not open to the front exterior of the display structure. The system further includes a plurality of display elements disposed within the plurality of display units.

Abstract: Systems, computer-implemented methods, and non-transitory computer readable media are provided for sharing medical data. The disclosed systems may be configured to create a first workgroup having a first knowledgebase. This first knowledgebase may be federated with a common knowledgebase, and with a second knowledgebase of a second workgroup. At least one of the first knowledgebase, common knowledgebase, and second knowledgebase may be configured to store data items comprising associations, signs, and evidence. The signs may comprise measurements and contexts, and the associations may describe the relationships between the measurements and contexts. The evidence may support these associations. The disclosed systems may be configured to receive a request from a user in the first workgroup, retrieve matching data items, and optionally then output to the user at least some of the retrieved matching data items. The request may comprise at least one of a first association and a first measurement.

Abstract: Methods for production of highly unsaturated fatty acids by marine microorganisms, including the heterotrophic marine dinoflagellate Crypthecodinium, using low levels of chloride ion are disclosed. Specifically, methods of increasing production of highly unsaturated fatty acids by marine microorganisms while growing in low chloride media by manipulating sodium ion and potassium ion levels. The invention also relates to methods of production of highly unsaturated fatty acids by marine organisms at low pH levels, and includes methods for generation of low pH tolerant strains.

Abstract: A shooting rest may be provided. The shooting rest may reduce the recoil, muzzle rise, and shock wave from firing a rifle or other weapon. A target may remain in the cross hairs while shooting, thus facilitating target memory or easy and fast target re-acquisition. When testing the amount of powder in a casing and weight of bullet in a reloaded round, the shooting rest may help eliminate movement variables so assessment of reloaded ammunition can be more accurately observed. The shooting rest may include a rear support, a front support, a frame, and a lock down bar to secure the front support to a shooting bench or table. The rear support may prevent the muzzle from moving upward and the front support may absorb some of the recoil energy to keep the target in sight. The frame may be secured by the lock down bar and may connect the front support to the table. Safety may be greatly enhanced by having the gun secured to a table during cleaning and maintenance operations.

Abstract: The present invention is directed to recombinant thraustochytrids that grow on xylose and cell cultures comprising the recombinant thraustochytrids as well as methods of producing cell cultures, biomasses, microbial oils, compositions, and biofuels using the recombinant thraustochytrids.