Patents by Inventor James A. Mezick

James A. Mezick has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6488940
    Abstract: The present invention relates to a method for treatment of mammalian skin conditions where stimulated connective tissue synthesis is beneficial, comprising treating skin in need of such treatment with a safe and effective amount of 17-&agr;-estradiol.
    Type: Grant
    Filed: August 10, 1998
    Date of Patent: December 3, 2002
    Assignee: Johnson & Johnson Consumer Companies, Inc.
    Inventors: Gerard J. Gendimenico, James A. Mezick
  • Publication number: 20010051167
    Abstract: The present invention relates to a method for treatment of mammalian skin conditions where stimulated connective tissue synthesis is beneficial, comprising treating skin in need of such treatment with a safe and effective amount of 17-&agr;-estradiol.
    Type: Application
    Filed: August 10, 1998
    Publication date: December 13, 2001
    Inventors: GERALD J. GENDIMENICO, JAMES A. MEZICK
  • Publication number: 20010000469
    Abstract: The present invention relates to a method for treatment of mammalian skin conditions where stimulated connective tissue synthesis is beneficial, comprising treating skin in need of such treatment with a safe and effective amount of 17-&agr;-estradiol.
    Type: Application
    Filed: December 19, 2000
    Publication date: April 26, 2001
    Inventors: Gerard J. Gendimenico, James A. Mezick
  • Patent number: 5643584
    Abstract: This invention relates to aqueous gel retinoid compositions and their methods of use. More specifically, the aqueous gel retinoid compositions of the invention utilize micronized particles of retinoids, particularly tretinoin, to provide an aqueous gel for topical application of such retinoids to the skin which minimizes skin irritation while retaining drug efficacy.
    Type: Grant
    Filed: May 18, 1995
    Date of Patent: July 1, 1997
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Richard K. Farng, Gerard J. Gendimenico, James A. Mezick, Shirley M. Ng, Stanley B. Wrobel, Jr.
  • Patent number: 5019569
    Abstract: The present invention is directed to the topical administration of a retinoid-containing pharmaceutical composition for reversing the effects of glucocorticoid-induced skin atrophy.
    Type: Grant
    Filed: August 31, 1989
    Date of Patent: May 28, 1991
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Albert M. Kligman, James A. Mezick, Robert J. Capetola
  • Patent number: 4889847
    Abstract: The present invention is directed to the topical administration of a retinoid-containing pharmaceutical composition for the prevention of glucocorticoid-induced skin atrophy.
    Type: Grant
    Filed: November 3, 1986
    Date of Patent: December 26, 1989
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Albert M. Kligman, James A. Mezick, Robert J. Capetola
  • Patent number: 4579844
    Abstract: A pharmaceutical composition for topical treatment of cutaneous disorders or disruptions characterized by skin inflammation or hyperproliferative epidermal activity comprises the combination of a topically active anti-inflammatory corticosteroid and a non-steroidal anti-inflammatory agent which is an inhibitor of prostaglandin synthetase selected from the group consisting of the hydratropic acid derivatives; acetylsalicylic acid; the pyrazolon derivatives; the fenamic acid derivatives; the aroyl-substituted pyrroles and the substituted arylacetohydroxamic acids in a pharmaceutically acceptable topical vehicle. Treatment of above cutaneous disorders may also be effected by concurrent therapy using separate applications of corticosteroid and non-steroid.
    Type: Grant
    Filed: March 22, 1984
    Date of Patent: April 1, 1986
    Assignee: Johnson & Johnson
    Inventors: David T. Rovee, John R. Marvel, James A. Mezick
  • Patent number: 4487782
    Abstract: Topical treatment of non-inflammatory acne by the administration of 13-cis-retinoic acid is disclosed.
    Type: Grant
    Filed: March 26, 1982
    Date of Patent: December 11, 1984
    Assignee: Ortho Pharmaceutical Corporation
    Inventor: James A. Mezick
  • Patent number: 4473565
    Abstract: A pharmaceutical composition for topical treatment of cutaneous disorders or disruptions characterized by skin inflammation or hyperproliferative epidermal activity comprises the combination of a topically active anti-inflammatory corticosteroid and a non-steroidal anti-inflammatory agent which is an inhibitor of prostaglandin synthetase selected from the group consisting of the hydratropic acid derivatives; acetylsalicylic acid; the pyrazolon derivatives; the fenamic acid derivatives; the aroyl-substituted pyrroles and the substituted arylacetohydroxamic acids in a pharmaceutically acceptable topical vehicle. Treatment of above cutaneous disorders may also be effected by concurrent therapy using separate applications of corticosteroid and non-steroid.
    Type: Grant
    Filed: November 19, 1982
    Date of Patent: September 25, 1984
    Assignee: Johnson & Johnson
    Inventors: David T. Rovee, John R. Marvel, James A. Mezick
  • Patent number: 4360518
    Abstract: A pharmaceutical composition for topical treatment of cutaneous disorders or disruptions characterized by skin inflammation or hyperproliferative epidermal activity comprises the combination of a topically active anti-inflammatory corticosteroid and a non-steroidal anti-inflammatory agent which is an inhibitor of prostaglandin synthetase selected from the group consisting of the hydratropic acid derivatives; acetylsalicylic acid; the pyrazolone derivatives; the fenamic acid derivatives; the aroyl-substituted pyrroles and the substituted arylacetohydroxamic acids in a pharmaceutically acceptable topical vehicle. Treatment of above cutaneous disorders may also be effected by concurrent therapy using separate applications of corticosteroid and non-steroid.
    Type: Grant
    Filed: March 17, 1981
    Date of Patent: November 23, 1982
    Assignee: Johnson & Johnson
    Inventors: David T. Rovee, John R. Marvel, James A. Mezick
  • Patent number: 4282216
    Abstract: A pharmaceutical composition for topical treatment of cutaneous disorders or disruptions characterized by skin inflammation or hyperproliferative epidermal activity comprises the combination of a topically active anti-inflammatory corticosteroid and a non-steroidal anti-inflammatory agent which is an inhibitor of prostaglandin synthetase selected from the group consisting of the hydratropic acid derivatives; acetylsalicylic acid; the pyrazolone derivatives; the fenamic acid derivatives; the aroyl-substituted pyrroles and the substituted arylacetohydroxamic acids in a pharmaceutically acceptable topical vehicle. Treatment of above cutaneous disorders may also be effected by concurrent therapy using separate applications of corticosteroid and non-steroid.
    Type: Grant
    Filed: August 6, 1979
    Date of Patent: August 4, 1981
    Assignee: Johnson & Johnson
    Inventors: D. Thomas Rovee, John R. Marvel, James A. Mezick
  • Patent number: 4185100
    Abstract: A pharmaceutical composition for topical treatment of cutaneous disorders or disruptions characterized by skin inflammation or hyperproliferative epidermal activity comprises the combination of a topically active anti-inflammatory corticosteroid and a non-steroidal anti-inflammatory agent which is an inhibitor of prostaglandin synthetase selected from the group consisting of the hydratropic acid derivatives; acetylsalicylic acid; the pyrazolone derivatives; the fenamic acid derivatives; the aroyl-substituted pyrroles and the substituted arylacetohydroxamic acids in a pharmaceutically acceptable topical vehicle. Treatment of above cutaneous disorders may also be effected by concurrent therapy using separate applications of corticosteroid and non-steroid.
    Type: Grant
    Filed: April 20, 1977
    Date of Patent: January 22, 1980
    Assignee: Johnson & Johnson
    Inventors: David T. Rovee, John R. Marvel, James A. Mezick
  • Patent number: 4073291
    Abstract: Tretinoin is incorporated in the adhesive mass of a dermatologically acceptable pressure-sensitive adhesive tape for the localized topical treatment of such skin conditions as acne and warts.
    Type: Grant
    Filed: July 28, 1976
    Date of Patent: February 14, 1978
    Assignee: Johnson & Johnson
    Inventors: John R. Marvel, James A. Mezick