Patents by Inventor James A. Profitt

James A. Profitt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aminoalkylthiodibenzoxepins and pharmaceutical use
    Patent number: 4837227
    Abstract: Novel aminoalkylthiodibenzoxepins, physiologically tolerable acid addition salts thereof, a method of preparing same, pharmaceutical and veterinary preparations including same and methods of treating by administering same are disclosed. These compounds are useful as analgesic, antidepressant and anticonvulsant agents. A process for selectively reducing olefins by alkaline earth metals in loweralkanols is also disclosed.
    Type: Grant
    Filed: May 28, 1985
    Date of Patent: June 6, 1989
    Assignee: Hoechst-Roussel Pharmaceuticals, Inc.
    Inventors: Helen H. Ong, Vernon B. Anderson, James A. Profitt
  • Aminoalkylthiodibenzothiepins
    Patent number: 4775683
    Abstract: Novel aminoalkylthiodibenzothiepins and related compounds, physiologically tolerable acid addition salts thereof, a method of preparing same, pharmaceutical and veterinary preparations including same and methods of treating by administering same are disclosed. These compounds are useful as antidepressant, analgetic, and anticonvulsant agents.
    Type: Grant
    Filed: February 13, 1987
    Date of Patent: October 4, 1988
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventors: Helen H. Ong, Vernon B. Anderson, James A. Profitt
  • Haloalkylthiodibenzothiepins
    Patent number: 4775682
    Abstract: Novel aminoalkylthiodibenzothiepins and related compounds, physiologically tolerable acid addition salts thereof, a method of preparing same, pharmaceutical and veterinary preparations including same and methods of treating by administering same are disclosed. These compounds are useful as antidepressant, analgetic, and anticonvulsant agents.
    Type: Grant
    Filed: February 13, 1987
    Date of Patent: October 4, 1988
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventors: Helen H. Ong, Vernon B. Anderson, James A. Profitt
  • Aminoalkylthiodibenzothiepins
    Patent number: 4775672
    Abstract: Novel aminoalkylthiodibenzothiepins and related compounds, physiologically tolerable acid addition salts thereof, a method of preparing same, pharmaceutical and veterinary preparations including same and methods of treating by administering same are disclosed. These compounds are useful as antidepressant, analgetic, and anticonvulsant agents.
    Type: Grant
    Filed: February 13, 1987
    Date of Patent: October 4, 1988
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventors: Helen H. Ong, Vernon B. Anderson, James A. Profitt
  • Aminoalkylthiodibenzothiepins
    Patent number: 4771069
    Abstract: Novel aminoalkylthiodibenzothiepins and related compounds, physiologically tolerable acid addition salts thereof, a method of preparing same, pharmaceutical and veterinary preparations including same and methods of treating by administering same are disclosed. These compounds are useful as antidepressant, analgetic, and anticonvulsant agents.
    Type: Grant
    Filed: February 11, 1987
    Date of Patent: September 13, 1988
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventors: Helen H. Ong, Vernon B. Anderson, James A. Profitt
  • Haloalkylthiodibenzothiepins
    Patent number: 4766143
    Abstract: Novel aminoalkylthiodibenzothiepins and related compounds, physiologically tolerable acid addition salts thereof, a method of preparing same, pharmaceutical and veterinary preparations including same and methods of treating by administering same are disclosed. These compounds are useful as antidepressant, analgetic, and anticonvulsant agents.
    Type: Grant
    Filed: February 12, 1987
    Date of Patent: August 23, 1988
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventors: Helen H. Ong, Vernon B. Anderson, James A. Profitt
  • Phenyl substituted carbamothioic acid esters
    Patent number: 4672138
    Abstract: Novel benzo[b]thiophenes, compositions containing same, process for the preparation thereof and methods of reducing blood pressure and producing diuresis by administration of the compounds and compositions are disclosed.
    Type: Grant
    Filed: February 3, 1986
    Date of Patent: June 9, 1987
    Assignee: Hoechst Roussel Pharmaceuticals Inc.
    Inventors: Helen H. Ong, James A. Profitt
  • Aminoalkylthiodibenzothiepins
    Patent number: 4668695
    Abstract: Novel aminoalkylthiodibenzothiepins and related compounds, physiologically tolerable acid addition salts thereof, a method of preparing same, pharmaceutical and veterinary preparations including same and methods of treating by administering same are disclosed. These compounds are useful as antidepressant, analgetic, and anticonvulsant agents.
    Type: Grant
    Filed: October 28, 1983
    Date of Patent: May 26, 1987
    Assignee: Hoechst Roussel Pharmaceuticals Inc.
    Inventors: Helen H. Ong, Vernon B. Anderson, James A. Profitt
  • Benzo[b]thiophenes
    Patent number: 4537976
    Abstract: Novel benzo[b]thiophenes, compositions containing same, process for the preparation thereof and methods of reducing blood pressure and producing diuresis by administration of the compounds and compositions are disclosed.
    Type: Grant
    Filed: December 5, 1983
    Date of Patent: August 27, 1985
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventors: Helen H. Ong, James A. Profitt
  • Benzo[b]thiophenes intermediates
    Patent number: 4528399
    Abstract: Novel benzo[b]thiophenes, compositions containing same, process for the preparation thereof and methods of reducing blood pressure and producing diuresis by administration of the compounds and compositions are disclosed.
    Type: Grant
    Filed: December 5, 1983
    Date of Patent: July 9, 1985
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventors: Helen H. Ong, James A. Profitt
  • Process for preparing substituted 1,3-dihydrospiro[benzo(c)thiophene]s
    Patent number: 4524207
    Abstract: Novel substituted 1,3-dihydrospiro[benzo(c)thiophene]s and methods of preparing the same are described. These compounds are useful as antidepressants and tranquilizers and intermediates therefor.
    Type: Grant
    Filed: July 21, 1983
    Date of Patent: June 18, 1985
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventors: Helen H. Ong, Vernon B. Anderson, James A. Profitt
  • Spiro[indoline-3,4'-piperidine]s and related compounds
    Patent number: 4477667
    Abstract: Novel spiro[indoline-3,4'-piperidine]s and related compounds and methods of preparing same are described. These compounds are useful as antidepressants, anticonvulsants and tranquilizers. Also described is a novel method of preparing indoline rings.
    Type: Grant
    Filed: December 18, 1981
    Date of Patent: October 16, 1984
    Assignee: American Hoechst Corporation
    Inventors: Helen H. Ong, James A. Profitt
  • Benzo[b]thiophenes
    Patent number: 4436748
    Abstract: Novel benzo[b]thiophenes, compositions containing same, process for the preparation thereof and methods of reducing blood pressure and producing diuresis by administration of the compounds and compositions are disclosed.
    Type: Grant
    Filed: April 22, 1981
    Date of Patent: March 13, 1984
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventors: Helen H. Ong, James A. Profitt
  • Antidepressive and tranquilizing substituted 1,3-dihydrospiro[benzo(c)thiophene]s
    Patent number: 4409229
    Abstract: Novel substituted 1,3-dihydrospiro[benzo(c)thiophene]s and methods of preparing the same are described. These compounds are useful as antidepressants and tranquilizers and intermediates therefor.
    Type: Grant
    Filed: October 20, 1981
    Date of Patent: October 11, 1983
    Assignee: Hoechst-Roussel Pharmaceuticals, Inc.
    Inventors: Helen H. Ong, Vernon B. Anderson, James A. Profitt
  • Spiro(indoline-3,4'-piperidine) and related compounds
    Patent number: 4408050
    Abstract: Novel spiro[indoline-3,4'-piperidine]s and related compounds and methods of preparing same are described. These compounds are useful as antidepressants, anticonvulsants and tranquilizers. Also described is a novel method of preparing indoline rings.
    Type: Grant
    Filed: December 18, 1981
    Date of Patent: October 4, 1983
    Assignee: American Hoechst Corporation
    Inventors: Helen H. Ong, James A. Profitt
  • Process for preparing spiro[indoline-3,4'-piperidine]s
    Patent number: 4379933
    Abstract: Novel spiro[indoline-3,4'-piperidine]s and related compounds and methods of preparing same are described. These compounds are useful as antidepressants, anticonvulsants and tranquilizers. Also described is a novel method of preparing indoline rings.
    Type: Grant
    Filed: December 18, 1981
    Date of Patent: April 12, 1983
    Assignee: American Hoechst Corporation
    Inventors: Helen H. Ong, James A. Profitt
  • Process for preparing spiro[indoline-3,4'-piperidine]s
    Patent number: 4379932
    Abstract: Novel spiro[indoline-3,4'-piperidine]s and related compounds and methods of preparing same are described. These compounds are useful as antidepressants, anticonvulsants and tranquilizers. Also described is a novel method of preparing indoline rings.
    Type: Grant
    Filed: December 18, 1981
    Date of Patent: April 12, 1983
    Assignee: American Hoechst Corporation
    Inventors: Helen H. Ong, James A. Profitt
  • Spiro[indoline-3,4'-piperidine]s
    Patent number: 4345081
    Abstract: Novel spiro[indoline-3,4'-piperidine]s and related compounds and methods of preparing same are described. These compounds are useful as antidepressants, anticonvulsants and tranquilizers. Also described is a novel method of preparing indoline rings.
    Type: Grant
    Filed: October 17, 1980
    Date of Patent: August 17, 1982
    Assignee: American Hoechst Corporation
    Inventors: Helen H. Ong, James A. Profitt
  • Spiro[indoline-3,4'-piperidine]s
    Patent number: 4307235
    Abstract: Novel spiro[indoline-3,4'-piperidine]s and related compounds and methods of preparing same are described. These compounds are useful as antidepressants, anticonvulsants and tranquilizers. Also described is a novel method of preparing indoline rings.
    Type: Grant
    Filed: February 15, 1980
    Date of Patent: December 22, 1981
    Assignee: American Hoechst Corporation
    Inventors: Helen H. Ong, James A. Profitt
  • Spiro[indoline-3,4'-piperidine]s
    Patent number: 4209625
    Abstract: Novel spiro[indoline-3,4'-piperidine]s and related compounds and methods of preparing same are described. These compounds are useful as antidepressants, anticonvulsants and tranquilizers. Also described is a novel method of preparing indoline rings.
    Type: Grant
    Filed: August 23, 1978
    Date of Patent: June 24, 1980
    Assignee: American Hoechst Corporation
    Inventors: Helen H. Ong, James A. Profitt