Patents by Inventor James Alexander DAVIES
James Alexander DAVIES has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9155838Abstract: A medicated module (100) is attachable to a drug delivery device (102). The medicated module (100) includes a housing (104) having a proximal end and a distal end, the proximal end has a connector (110) configured for attachment to a drug delivery device (102). The distal end contains a shuttle (112). A first needle (114) is fixed in the housing (104) and a second needle (116) is fixed in the shuttle (112). The medicated module (100) also includes a reservoir (118) in the housing (104) comprising a medicament (12). Further, the medicated module (100) includes a guard assembly (122) positioned in the housing (104) and configured to move in an axial direction during application to an injection site. Preferably, the medicated module (100) is locked out after at least two injections of the medicament (105) contained in the drug delivery device (102).Type: GrantFiled: February 1, 2011Date of Patent: October 13, 2015Assignee: Sanofi-Aventis Deutschland GmbHInventors: Simon Lewis Bilton, Malcolm Stanley Boyd, James Alexander Davies, John David Cross, Aled Meredydd James, David Moore, Daniel Thomas De Sausmarez Lintell
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Patent number: 9089649Abstract: A medicated module (4) for an injection system to co-deliver at least two medicaments (1, 2) is disclosed where a primary delivery device (7) containing a primary medicament (1) accepts a medicated module (4) containing a single dose of a secondary medicament (2) and where both medicaments (1, 2) are delivered through a single hollow needle (3, 16, 21, 31).Type: GrantFiled: June 1, 2010Date of Patent: July 28, 2015Assignee: Sanofi-Aventis Detuschland GmbHInventors: James Alexander Davies, Steven Wimpenny, Daniel Thomas De Sausmarez Lintell, Malcolm Stanley Boyd, Naceur Rekaya, Simon Lewis Bilton, John David Cross, David Moore, Graham Jay, Ross Douglas MacArthur, Michael James David Heald, Christopher James Smith
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Patent number: 9033933Abstract: A medicated module for an injection system to co-deliver at least two medicaments is disclosed where a primary delivery device containing a primary medicament accepts a medicated module containing a single dose of a secondary medicament and where both medicaments are delivered through a single hollow needle. The medicated module is configured so that it will first deliver both the primary and secondary medicaments and then, if needed, a dose(s) of additional primary medicament. The module also contains a needle guard that locks the first dose delivery, but can be manually overridden by a user to perform a second or subsequent injection of primary medicament.Type: GrantFiled: February 1, 2011Date of Patent: May 19, 2015Assignee: SANOFI-AVENTIS DEUTSCHLAND GMBHInventors: Malcolm Stanley Boyd, James Alexander Davies, Daniel Thomas De Sausmarez Lintell
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Patent number: 8979791Abstract: A medicated module comprising a connecting body configured for attachment to a drug delivery device. A first needle is fixed within the connecting body and an outer body operatively coupled to the connecting body. A needle guard operatively coupled to the outer body and a biasing member positioned between the outer body and needle guard. A second needle fixed within the outer body and a recess within the connecting body defines a reservoir. The reservoir contains at least one dose of a medicament and is configured for fluid communication with the first and second needle.Type: GrantFiled: June 1, 2010Date of Patent: March 17, 2015Assignee: Sanofi-Aventis Deutschland GmbHInventors: James Alexander Davies, Steven Wimpenny, Daniel Thomas De Sausmarez Lintell, Malcolm Stanley Boyd, Naceur Rekaya, Simon Lewis Bilton, John David Cross
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Publication number: 20140303555Abstract: The invention is related to an apparatus comprising a dispense interface comprising a lockout element for use with a drug delivery device, the lockout element comprising at least one spring component removeably maintained in a respective first position such that when the dispense interface is first attached and then removed from said drug delivery device, each spring component moves into a respective second position, which respective second position is configured to prevent said dispense interface from being reattached to a drug delivery device.Type: ApplicationFiled: April 26, 2012Publication date: October 9, 2014Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventors: James Alexander Davies, Simon Lewis Bilton, David Moore, Steven Wimpenny, Christopher Nigel Langley
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Patent number: 8753319Abstract: A method and system for delivering a user-settable dose of a first medicament and a non-user settable dose of a second medicament through a single dose setter and a single dispense interface. The drug delivery system includes a drug delivery device and a medicated module. The drug delivery device comprises a single dose setter operably connected to a primary reservoir containing the first medicament. The medicated module comprises (i) a collapsible feature holding the second medicament and (ii) the single dispense interface having an output needle. Further, the drug delivery device and medicated module are each configured such that the single dose setter is mechanically linked to the collapsible feature after attachment of the medicated module to the drug delivery device.Type: GrantFiled: October 31, 2011Date of Patent: June 17, 2014Assignee: Sanofi-Aventis Deutschland GmbHInventors: James Alexander Davies, Steven Wimpenny, Daniel Thomas De Sausmarez Lintell, David Sanders, Paul Richard Draper
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Publication number: 20140128817Abstract: A medicated module (4) for an injection system to co-deliver at least two medicaments is disclosed where a primary delivery device containing a primary medicament accepts a medicated module (4) containing a single dose of a secondary medicament (2) and where both medicaments are delivered through a single hollow needle (5). The medicated module (4) is user selectable so that it will deliver both the primary (1) and secondary medicaments (2), or only the primary medicament (1). The module (4) also contains a guard (42) that locks after dose delivery.Type: ApplicationFiled: January 13, 2014Publication date: May 8, 2014Applicant: Sanofi-Aventis Deutschland GmbHInventors: James Alexander Davies, Steven Wimpenny, Daniel Thomas De Sausmarez Lintell, Malcolm Stanley Boyd, Naceur Rekaya, Simon Lewis Bilton, John David Cross
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Publication number: 20140066879Abstract: The invention is related to an apparatus comprising an inner body of a dispense interface and a manifold, wherein the inner body comprises a recess configured to receive a distal needle from a distal end of the inner body, a first fluid reservoir and a second fluid reservoir, and wherein the manifold comprises a filling block configured to redirect flow, a fluid groove arrangement configured to provide a fluid connection to the filling block, wherein the inner body and the manifold are assembled such that there is formed a channel providing a fluid connection from the first fluid reservoir and the second fluid reservoir, respectively, via the fluid groove arrangement and the filling block to the recess.Type: ApplicationFiled: April 26, 2012Publication date: March 6, 2014Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventors: Marc Holtwick, James Alexander Davies, Simon Lewis Bilton, David Moore, Steven Wimpenny, Christopher Nigel Langley
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Patent number: 8663172Abstract: A medicated module (4) for an injection system to co-deliver at least two medicaments is disclosed where a primary delivery device containing a primary medicament accepts a medicated module (4) containing a single dose of a secondary medicament (2) and where both medicaments are delivered through a single hollow needle (5). The medicated module (4) is user selectable so that it will deliver both the primary (1) and secondary medicaments (2), or only the primary medicament (1). The module (4) also contains a guard (42) that locks after dose delivery.Type: GrantFiled: June 1, 2010Date of Patent: March 4, 2014Assignee: Sanofi-Aventis Deutschland GmbHInventors: James Alexander Davies, Steven Wimpenny, Daniel Thomas De Sausmarez Lintell, Malcolm Stanley Boyd, Naceur Rekaya, Simon Lewis Bilton, John David Cross
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Publication number: 20140054295Abstract: The present invention inter alia relates to an apparatus and a method. The apparatus comprises a body part and a cover part, wherein the body part and the cover part are configured to at least partially form a fluid channel between a surface of the body part and a surface of the cover part. The surfaces of the body part and the cover part may be facing surfaces. The method comprises manufacturing the apparatus according to the present invention.Type: ApplicationFiled: April 26, 2012Publication date: February 27, 2014Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventors: Marc Holtwick, James Alexander Davies, Simon Lewis Bilton, David Moore, Steven Wimpenny, Christopher Nigel Langley
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Publication number: 20140049041Abstract: The invention relates to a dispense interface for use with a drug delivery device with an inner body and with a lockout element, wherein the lockout element is coupled to the inner body, wherein the lockout element is movable from a receptive condition to a locked condition, wherein in the receptive condition the dispense interface is attachable to the drug delivery device, wherein in the locked condition the dispense interface is not-attachable to the drug delivery device and wherein the lockout element is configured to move from the receptive condition to the locked condition when said dispense interface is attached to and detached from said drug delivery device. The invention solves the technical problem of reducing the risk of reuse of a dispense interface, after it has already been used with a drug delivery device.Type: ApplicationFiled: April 26, 2012Publication date: February 20, 2014Inventors: Ilona Eggert, James Alexander Davies, Simon Lewis Bilton, David Moore, Steven Wimpenny, Christopher Nigel Langley
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Publication number: 20140052079Abstract: The invention faces the technical problem of reducing the uncertainty over exact doses ejected from a medical device and at the same time providing a homogeneous, but controlled mixture of at least two fluids while a simple production should be maintained. A medical device comprising a first valve, a second valve, a first pre-valve ullage, a second pre-valve ullage, a post-valve ullage with a first end and a second end and a needle is presented. The first pre-valve ullage is connected to the post-valve ullage by the first valve and the second pre-valve ullage is connected to the post-valve ullage by the second valve. A first fluid is guidable from the first pre-valve ullage to the post-valve ullage and a second fluid is guidable from the second pre-valve ullage to the post-valve ullage.Type: ApplicationFiled: April 26, 2012Publication date: February 20, 2014Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventors: Ilona Eggert, James Alexander Davies, Simon Lewis Bilton, David Moore, Steven Wimpenny, Christopher Nigel Langley
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Publication number: 20140052077Abstract: The invention faces the technical problem of providing a tight connection between a tube and an dispense interface, while at the same time the biocompatibility of the connection can be improved. The technical problem is solved by an apparatus comprising a tube configured to guide a medium and a dispense interface. The tube comprises a first opening and a second opening, while the dispense interface comprises a recess. The recess has a first opening and a second opening and the tube is at least in part inserted into the recess. The tube is permanently affixed to the dispense interface by a combination of an interference fit and an adhesive, such that the interference fit prevents the adhesive from contaminating the medium.Type: ApplicationFiled: April 26, 2012Publication date: February 20, 2014Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventors: Marc Holtwick, Jeffrey Zajac, James Alexander Davies, Simon Lewis Bilton, David Moore, Steven Wimpenny, Christopher Nigel Langley
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Publication number: 20140046267Abstract: The invention is related to a manifold comprising at least two valve receptacles, further comprising a fluid groove arrangement comprising at least two fluid grooves, wherein a first fluid groove of the at least two fluid grooves has a starting point near a first valve receptacle of the at least two valve receptacles and an end point near a second valve receptacle of the at least two valve receptacles and wherein a second fluid groove of the at least two fluid grooves has a starting point near a second valve receptacle of the at least two valve receptacles. The invention is further related to an apparatus comprising a manifold of the aforementioned kind and further comprising an inner body of a dispense interface.Type: ApplicationFiled: April 26, 2012Publication date: February 13, 2014Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventors: Marc Holtwick, James Alexander Davies, Simon Lewis Bilton, David Moore, Steven Wimpenny, Christopher Nigel Langley
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Publication number: 20140042741Abstract: The invention relates to a dispense interface for use with a drug delivery device with an inner body and with a lockout element, wherein the lockout element is coupled to the inner body, wherein the lockout element is movable from a receptive condition to a locked condition, wherein in the receptive condition the dispense interface is attachable to the drug delivery device, wherein in the locked condition the dispense interface is not-attachable to the drug delivery device and wherein the lockout element is configured to move from the receptive condition to the locked condition when said dispense interface is attached to and detached from said drug delivery device. The invention solves the technical problem of reducing the risk of reuse of a dispense interface, after it has already been used with a drug delivery device.Type: ApplicationFiled: April 26, 2012Publication date: February 13, 2014Inventors: Ilona Eggert, James Alexander Davies, Simon Lewis Bilton, David Moore, Steven Wimpenny, Christopher Nigel Langley
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Publication number: 20140039390Abstract: The invention is related to an apparatus comprising a dispense interface for use with a drug delivery device, the dispense interface comprising a lockout element being arranged at least partially between an outer body of the dispense interface and an inner body of the dispense interface and wherein the lockout element is configured to be removeably maintained in a first position, such that when the dispense interface is first attached and then removed from said drug delivery device, the lockout element moves into a second position, wherein the lockout element in the second position is configured to prevent said dispense interface from being reattached to a drug delivery device.Type: ApplicationFiled: April 26, 2012Publication date: February 6, 2014Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventors: Marc Holtwick, Ilona Eggert, James Alexander Davies, Simon Lewis Bilton, David Moore, Steven Wimpenny, Christopher Nigel Langley
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Publication number: 20140005603Abstract: A dispense interface for use with a drug delivery device. The dispense interface comprises a main outer body and an inner body. The inner body may be configured for connection to a drug delivery device and defines a first reservoir and a second reservoir. A first piercing needle is in fluid communication with the first reservoir and positioned for piercing a first cartridge of a drug delivery device. A second piercing needle is provided and in fluid communication with the second reservoir and positioned for piercing a second cartridge contained with a drug delivery device. A manifold is positioned adjacent the inner body and comprises a fluid groove arrangement. A valve arrangement is positioned between the inner body and the manifold and controls fluid communication of a first fluid contained in the first cartridge and a second fluid contained in the second cartridge by way of the fluid groove arrangement to a holding chamber.Type: ApplicationFiled: February 14, 2012Publication date: January 2, 2014Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventors: Marc Holtwick, Ilona Eggert, James Alexander Davies, Simon Lewis Bilton, David Moore, Steven Wimpenny, Christopher Nigel Langley, Jeffrey Zajac
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Publication number: 20130289488Abstract: A cartridge assembly for use with a drug delivery device comprises: a cartridge holder defining an aperture therethrough, with a blocking feature and at least one holder coding feature; and a cartridge with at least one cartridge coding feature; wherein when the cartridge is inserted into the cartridge holder, the cartridge coding feature mates with the holder coding feature, moving the blocking feature or allowing the blocking feature to move.Type: ApplicationFiled: December 20, 2011Publication date: October 31, 2013Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventors: Ralf Riess, Stefan Trinkle, James Senior, James Alexander Davies, Andrew Gordon Wallace
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Publication number: 20130253433Abstract: A cartridge assembly for use with a drug delivery device is specified. The cartridge assembly comprises a cartridge with a retention cap and a cartridge holder. According to one aspect, the cartridge and the cartridge holder may be configured to be fixed to each other in a predetermined position According to another aspect, the retention cap comprises at least one coding feature configured to affix said cartridge to said cartridge holder in the predetermined position by the mating of said coding feature with a corresponding coding feature on the cartridge holder.Type: ApplicationFiled: December 21, 2011Publication date: September 26, 2013Inventors: James Senior, James Alexander Davies
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Publication number: 20130237922Abstract: A method and system for sequentially dispensing a non-user settable dose of one medicament followed by a user-settable dose of a primary medicament. A medicated module may be attachable to a drug delivery device and the drug delivery device may have a drug reservoir holding a first medicament. The medicated module includes a first needle, a second needle, a deformable membrane, and a second medicament. The deformable membrane facilitates sequential dosing of the second medicament followed by the first medicament. After the medicated module is attached to the drug delivery device, (i) the first needle is in fluid communication with the drug reservoir and (ii) the deformable membrane prevents fluid communication between the first and second needle. The deformable membrane prevents fluid communication between the first and second needle until substantially all of the second medicament is dispensed.Type: ApplicationFiled: October 31, 2011Publication date: September 12, 2013Inventors: James Alexander Davies, David Sanders, David Moore, Steven Wimpenny