Patents by Inventor James B. Garrett

James B. Garrett has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant phytases and methods of making and using them
    Publication number: 20040091968
    Abstract: A purified and modified phytase enzyme from Escherichia coli K12 appA phytase is provided. The enzyme has phytase activity and improved thermal tolerance as compared with the wild-type enzyme. In addition, the enzyme has improved protease stability at low pH. Glycosylation of the modified phytase provided a further improved enzyme having improved thermal tolerance and protease stability. The enzyme can be produced from native or recombinant host cells and can be used to aid in the digestion of phytate where desired. In particular, the phytase of the present invention can be used in foodstuffs to improve the feeding value of phytate rich ingredients.
    Type: Application
    Filed: June 20, 2003
    Publication date: May 13, 2004
    Inventors: Jay M. Short, Keith Kretz, Kevin A. Gray, Nelson R. Barton, James B. Garrett, Eileen O'Donoghue, Eric J. Mather
  • Phytases, nucleic acids encoding them and methods for making and using them
    Publication number: 20030103958
    Abstract: The invention provides isolated and recombinant phytase enzymes. In one aspect, the phytases are produced by modification of the wild type appA of E. coli. The enzyme can be produced from recombinant host cells. The phytases of the invention can be used to aid in the digestion of phytate where desired. In particular, the phytases of the invention can be used in foodstuffs to improve the feeding value of phytate rich ingredients. The phytases of the invention can be thermotolerant and/or thermostable. Also provided are methods for obtaining a variant polynucleotide encoding a phytase and for obtaining a phytase with thermostability or thermotolerant at high or low temperatures.
    Type: Application
    Filed: May 24, 2002
    Publication date: June 5, 2003
    Applicant: Diversa Corporation
    Inventors: Jay M. Short, Keith Kretz, Kevin A. Gray, Nelson R. Barton, James B. Garrett, Eileen O'Donoghue, Eric J. Mathur
  • Recombinant bacterial phytases and uses thereof
    Publication number: 20020136754
    Abstract: A purified and modified phytase enzyme from Escherichia coli K12 appA phytase is provided. The enzyme has phytase activity and improved thermal tolerance as compared with the wild-type enzyme. In addition, the enzyme has improved protease stability at low pH. Glycosylation of the modified phytase provided a further improved enzyme having improved thermal tolerance and protease stability. The enzyme can be produced from native or recombinant host cells and can be used to aid in the digestion of phytate where desired. In particular, the phytase of the present invention can be used in foodstuffs to improve the feeding value of phytate rich ingredients.
    Type: Application
    Filed: May 24, 2001
    Publication date: September 26, 2002
    Inventors: Jay M. Short, Keith A. Kretz, Kevin A. Gray, Nelson Robert Barton, James B. Garrett, Eileen O' Donoghue, Eric J. Mathur