Abstract: The invention provides nucleic acid therapeutics and methods for using these nucleic acid therapeutics in the treatment of complement-related disorders.

Abstract: A method of making a waveguide for a radar system includes forming an additive manufacturing build of a waveguide by forming an initial layer, followed by forming a succession of build layers on the initial layer in a build direction from the initial layer towards a final layer. Forming the succession of build layers includes forming an overhanging feature supported by a support formed in the succession of build layers.

Abstract: A radio frequency (RF) waveguide comprising a channel, a filter, and a support bridge. The channel can comprise an outer wall defining an inner cavity configured to propagate electromagnetic waves. The filter can be disposed in the inner cavity of the channel and can comprise a perimeter edge and an aperture. The support bridge can comprise a first interface connected to an inner surface of the outer wall at a first location, and a second interface connected to the filter at a position between the perimeter edge and the aperture of the filter to support the filter within the channel. The support bridge can remain in place as connected to the filter, and the filter and waveguide can operate without interference from the support bridge, meaning that the waveguide meets all performance specifications and functions as intended for a particular application even with the support bridge left in place.

Abstract: A radio frequency (“RF”) waveguide device fabricated by additive manufacturing is provided that includes a RF channel comprising a wall and a RF component comprising an unsupported span extending from the wall of the RF channel. The unsupported span can include at least one unsupported surface extending from the wall at an oblique angle relative to the wall. The RF component formed in this manner with additive manufacturing does not negatively impact the RF performance of the RF waveguide.

Abstract: A circuit assembly is provided and includes a printed circuit board (PCB) having a circuit element region and defining a trench surrounding an entirety of the circuit element region, a circuit element disposed within the circuit element region of the PCB; and a Faraday wall. The Faraday wall includes a solid, unitary body having a same shape as the trench. The Faraday wall is disposed within the trench to surround an entirety of the circuit element.

Abstract: An antenna and method of manufacturing an antenna. The antenna includes a radiator feed layer, a first radiator patch assembly attached to the radiator feed layer, and a second radiator patch assembly attached to the radiator feed layer. The first radiator patch assembly is separated from the second radiator patch assembly by an air gap. The first radiator patch assembly is attached to the radiator feed layer and the second radiator patch assembly is attached to the radiator feed layer separated from the first radiator patch assembly by the air gap.

Abstract: A RAMP-radio frequency (RAMP-RF) assembly is provided and includes an RF panel including a microstrip interface, a plate including a stripline interface and a microstrip-to-stripline transition element operably connectable to the microstrip interface and to the stripline interface.

Abstract: A method of making a waveguide for a radar system includes forming an additive manufacturing build of a waveguide by forming an initial layer, followed by forming a succession of build layers on the initial layer in a build direction from the initial layer towards a final layer. Forming the succession of build layers includes forming an overhanging feature supported by a support formed in the succession of build layers.

Abstract: Bulk goods are transported on a rail network to a terminal which includes a loading with a metering device for measuring an amount of the bulk goods loaded or unloaded. At the terminal there is a control hub connecting to a plurality of portable hand held field computers and a communication system for communication with the rail network to obtain a Car Location Message (CLM), a way bill and mechanical data for each of the railcars. An input to the hub is provided by a plurality of self-powered scanning stations each including an RFID reader having an antenna for reading the RFID tag of an adjacent rail car where each scanning station has two radar proximity transducers responsive to presence of a rail car where the RFID reader has a quiescent mode and the radar proximity detectors activate the reader from the quiescent mode on detection of a railcar.

Abstract: A defect prediction method for a device manufacturing process involving processing a portion of a design layout onto a substrate, the method including: identifying a hot spot from the portion of the design layout; determining a range of values of a processing parameter of the device manufacturing process for the hot spot, wherein when the processing parameter has a value outside the range, a defect is produced from the hot spot with the device manufacturing process; determining an actual value of the processing parameter; determining or predicting, using the actual value, existence, probability of existence, a characteristic, or a combination thereof, of a defect produced from the hot spot with the device manufacturing process.

Abstract: A circuit assembly is provided and includes a printed circuit board (PCB) having a circuit element region and defining a trench surrounding an entirety of the circuit element region, a circuit element disposed within the circuit element region of the PCB; and a Faraday wall. The Faraday wall includes a solid, unitary body having a same shape as the trench. The Faraday wall is disposed within the trench to surround an entirety of the circuit element.

Abstract: A RAMP-radio frequency (RAMP-RF) assembly is provided and includes an RF panel including a microstrip interface, a plate including a stripline interface and a microstrip-to-stripline transition element operably connectable to the microstrip interface and to the stripline interface.

Abstract: A circuit assembly is provided and includes a printed circuit board (PCB) having a circuit element region and defining a trench surrounding an entirety of the circuit element region, a circuit element disposed within the circuit element region of the PCB; and a Faraday wall. The Faraday wall includes a solid, unitary body having a same shape as the trench. The Faraday wall is disposed within the trench to surround an entirety of the circuit element.

Abstract: A defect prediction method for a device manufacturing process involving processing a portion of a design layout onto a substrate, the method including: identifying a hot spot from the portion of the design layout; determining a range of values of a processing parameter of the device manufacturing process for the hot spot, wherein when the processing parameter has a value outside the range, a defect is produced from the hot spot with the device manufacturing process; determining an actual value of the processing parameter; determining or predicting, using the actual value, existence, probability of existence, a characteristic, or a combination thereof, of a defect produced from the hot spot with the device manufacturing process.

Abstract: An antenna and method of manufacturing an antenna. The antenna includes a radiator feed layer, a first radiator patch assembly attached to the radiator feed layer, and a second radiator patch assembly attached to the radiator feed layer. The first radiator patch assembly is separated from the second radiator patch assembly by an air gap. The first radiator patch assembly is attached to the radiator feed layer and the second radiator patch assembly is attached to the radiator feed layer separated from the first radiator patch assembly by the air gap.

Abstract: Bulk goods are transported on a rail network to a terminal which includes a loading with a metering device for measuring an amount of the bulk goods loaded or unloaded. At the terminal there is a control hub connecting to a plurality of portable hand held field computers and a communication system for communication with the rail network to obtain a Car Location Message (CLM), a way bill and mechanical data for each of the railcars. An input to the hub is provided by a plurality of self-powered scanning stations each including an RFID reader having an antenna for reading the RFID tag of an adjacent rail car where each scanning station has two radar proximity transducers responsive to presence of a rail car where the RFID reader has a quiescent mode and the radar proximity detectors activate the reader from the quiescent mode on detection of a railcar.

Abstract: In a method or apparatus for transporting bulk goods by rail cars on a rail network to a rail car handling terminal where the handling terminal includes a loading and/or unloading system with a metering device for measuring an amount of the bulk goods loaded or unloaded. At the terminal there is a center control data hub connecting to a plurality of portable hand held field computers and a communication system for communication with the rail network to obtain a Car Location Message (CLM), a way bill and mechanical data for each of the rail cars. The center control hub generates data indicating a current stage of each of the railcars and a signal indicative that a rail car can be transferred from one stage to another stage to the portable computers to control transfer of the rail car from one stage to the next stage.

Abstract: A stripline radio-frequency (RF) connection interface is provided and includes first and second printed circuit boards (PCBs). The first PCB includes a first trace, ground planes at opposite sides of the first trace, dielectric material interposed between the first trace and the ground planes and a first end. The first end is formed as a first rabbet at which the first trace is exposed. The second PCB includes a second trace, ground planes at opposite sides of the second trace, dielectric material interposed between the second trace and the ground planes and a second end. The second end is formed as a second rabbet, which is substantially identical to the first rabbet, at which the second trace is exposed. The first and second ends are mated in a shiplap joint to electrically couple the first and second traces.

Abstract: An appendage protection assembly for an infant includes a set of sleeves. Each sleeve has first end that is open so that the first end is configured to insert a respective appendage of the infant into the sleeve. The sleeve is configured to insulate the respective appendage and to shield the respective appendage from contact with a device that is coupled to the respective appendage. Each of a set of slits is positioned in a second end of a respective sleeve and extends into opposing sides of the respective sleeve to define a pair of flaps. The pair of flaps is configured to be separated to allow access to digits of the respective appendage that is positioned in the respective sleeve. Each of a set of closures that is coupled to a respective sleeve proximate to an associated slit is positioned to selectively close the associated slit.