Abstract: Gene editing complexes are specifically directed to cannabinoid sequences, such as tetrahydrocannabinol (THC), for excision or inactivation of these sequences. The disclosure is directed to the inhibition of synthesis of THC in a cannabis plant. In doing so, THC would never become an active compound within the plant chemistry and chemotype, thereby eliminating the chance of CBD extracts being contaminated with THC.

Abstract: In the secured pen holder of U.S. Pat. No. 6,167,596, a first resilient engagement between cover and base provides an indication of the replacement state in which the pen assembly can be replaced. A second resilient engagement between cover and base provides an indication of the use position in which the pen is held within the holder for use. A third resilient engagement between transport and base provides an indication that the transport is resiliently held in place at a position when the transport wall holds the pen tether and stop in place during the use state.

Abstract: A pen and pen holder arrangement provides security for retaining the pen and in which no tools are required to replace a used up pen. A pen with a flexible tether that terminates in a ball is employed together with a holder that receives the ball. The holder has a base with an opening adequate to pass the ball through and a transport that rotates within the base so that the ball can be moved from an insertion state to a holding state. In the holding state, the track has a dimension that holds the ball within the holder. A rotatable base cover that rotates with the transport obscures the transport from view and has a longitudinal slot opening enlarged at one end to permit the ball to be passed into the holder and otherwise a slot to permit the tether to move with the ball into the holding state.

Abstract: A nonconstrained, total great toe joint implant for the metatarsophalangeal joint made of a first component with a convex, partially spherical surface ending in a rear surface from which a longitudinally asymmetric implantation stem projects and having a flange on the dorsal side of the implant which extends the convex surface past the rear surface. The rear surface is inclined 10.degree. relative to a normal plane which intersects this surface. The metatarsal bone is resected accordingly. The phalangeal implant component is made of a base with a stem for placement in a bone cavity, projecting from a rear side thereof and having a low-friction, concavely curved insert affixed to the base which slidably engages and cooperates with the convex surface of the metatarsal implant component.

Abstract: An equalizer employed with a receiver for cancelling an interfering signal due to low cross-polarization isolation. The present equalizer provides a simple and inexpensive cross-polarization interference cancellation system. The equalizer uses an error signal generated in a residual carrier detector to determine the magnitude of an interfering signal and inputs a cancelling signal to the co-polarized channel until power in the error signal is minimized. In the equalizer, the determination of the magnitude of the interfering signal is performed at baseband (after demodulation but prior to data detection) and the cancellation is performed at RF, prior to dispersive microwave elements. In the receiver, co- and cross-polarized signals are received and amplified. A copy of the cross channel input signal is supplied to each receiver channel. An RF vector modulator is used to control the phase and amplitude of the cross-polarized signal prior to summation with a desired co-polarized signal.

Abstract: A pen and penholder combination includes a pen portion. An elongated flexible tether attaches on one end to the pen and on another end to a stop. A disk with a hole formed therein is slidingly received on the tether. The penholder is permanently securable to a writing surface. The penholder has a penholder surface with an upper and lower face. A disk securing slot is formed in the penholder surface. The slot is shaped and dimensioned to receive the stop therethrough and to receive the disk therethrough when the disk is oriented substantially perpendicular to the penholder surface. After the disk is passed through the slot and when it is not oriented substantially perpendicular to the penholder surface it abutts against the bottom face of the surface and cannot be passed through the slot.

Abstract: An automatic teller machine (ATM) with an operable front panel and an openable service panel is securely enclosed in an enclosure. The enclosure includes a first side wall extending at least from a floor at a first side of the ATM up, over and down to the floor on the second side of the ATM. A front wall with a cut-out zone therein, is provided which moves between an inward position and an outward position. In its position the front wall is secured to the first side wall. In its outward position the front wall is spaced from the first side wall. The cut-out zone has a perimeter sized and shaped to permit access to the operable front panel of the ATM when the front wall is in its inward position. Together the first side wall and the front wall define a first enclosure. A second side wall is connected to and extends inwardly from the front wall.

Abstract: A compact, secure enclosure for an automatic teller machine is provided. The automatic teller machine is of the type having a secure front panel and on operable rear panel. The enclosure is defined by a closed wall. The wall has a forward portion in which the automatic teller machine is located and a rearward portion which permits servicing of the automatic teller machine. The closed wall has a cut-out zone extending a substantial distance around the forward portion of the wall. The height of the cut-out zone is sufficient to accommodate the front face of the automatic teller machine. Within the forward portion of the enclosure a base is mounted which is capable of supporting the automatic teller machine. The base can be rotated 180.degree. so that the automatic teller machine when supported thereon can assume at least three significant positions.

Abstract: The secure enclosure for an automatic teller has a rear wall which moves between a forward position defining a smaller enclosure and a rearward position defining a larger enclosure. The rear wall has side and top panels which extend forward from the rear wall and which nest into the main walls of the enclosure. In the extended state, these panels provide the wall continuity that defines an extended yet continually secure enclosure. A locked door in one of the side panels provides personnel access when the enclosure is in its extended state. Yet this locked door is nested in the main walls and thus unaccessible when the enclosure is in its telescoped or nested state.