Patents by Inventor James Blinn

James Blinn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • THERAPEUTIC COMPOSITIONS AND METHODS FOR TREATING CANCER IN COMBINATION WITH ANALOGS OF INTERLEUKIN PROTEINS
    Publication number: 20220251191
    Abstract: Provided are compositions and methods for treating cancer by administering antiCD47 mAbs and anti-CD47 fusion proteins with distinct functional profiles or chimeric antigen receptor (CAR)-bearing immune effector cells in combination with analogs of interleukin proteins.
    Type: Application
    Filed: November 16, 2021
    Publication date: August 11, 2022
    Inventors: James BLINN, John MCKEARN, Joseph MONAHAN, William R. STROHL, Robyn PURO, John RICHARDS, Daniel S. PEREIRA, Juan C. ALMAGRO
  • Indazole retinoic acid receptor-related orphan receptor modulators and uses thereof
    Patent number: 9884847
    Abstract: Provided herein are compounds of the formulas (I) and (II): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of Retinoic Acid Receptor-Related Orphan Receptor regulated diseases and disorders.
    Type: Grant
    Filed: July 24, 2015
    Date of Patent: February 6, 2018
    Assignee: INNOV17 LLC
    Inventors: Anderson Gaweco, Jefferson Tilley, James Blinn
  • Benzimidazole retinoic acid receptor-related orphan receptor modulators and uses thereof
    Patent number: 9771374
    Abstract: Provided herein are compounds of the formulas (I) and (II): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of Retinoic Acid Receptor-Related Orphan Receptor regulated diseases and disorders.
    Type: Grant
    Filed: July 24, 2015
    Date of Patent: September 26, 2017
    Assignee: INNOV17 LLC
    Inventors: Anderson Gaweco, Jefferson Tilley, James Blinn
  • AZAINDOLE RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTOR MODULATORS AND USES THEREOF
    Publication number: 20170217956
    Abstract: Provided herein are compounds of the formulas (I) and (II), as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of Retinoic Acid Receptor-Related Orphan Receptor regulated diseases and disorders.
    Type: Application
    Filed: July 24, 2015
    Publication date: August 3, 2017
    Applicant: INNOV17 LLC
    Inventors: Anderson Gaweco, Jefferson Tilley, James Blinn
  • ROR modulators and their uses
    Patent number: 9708268
    Abstract: The invention relates to ROR modulators; compositions comprising an effective amount of a ROR modulator; and methods for treating or preventing diseases associated with ROR.
    Type: Grant
    Filed: April 30, 2013
    Date of Patent: July 18, 2017
    Assignee: INNOV17 LLC
    Inventors: Anderson Gaweco, Jefferson W. Tilley, John Walker, Samantha Palmer, James Blinn
  • Sulfonamide retinoic acid receptor-related orphan receptor modulators and uses thereof
    Patent number: 9701663
    Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of Retinoic Acid Receptor-Related Orphan Receptor regulated diseases and disorders.
    Type: Grant
    Filed: July 24, 2015
    Date of Patent: July 11, 2017
    Assignee: INNOV17 LLC
    Inventors: Anderson Gaweco, Jefferson Tilley, James Blinn
  • BENZIMIDAZOLE RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTOR MODULATORS AND USES THEREOF
    Publication number: 20170190712
    Abstract: Provided herein are compounds of the formulas (I) and (II): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of Retinoic Acid Receptor-Related Orphan Receptor regulated diseases and disorders.
    Type: Application
    Filed: July 24, 2015
    Publication date: July 6, 2017
    Inventors: Anderson Gaweco, Jefferson Tilley, James Blinn
  • INDAZOLE RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTOR MODULATORS AND USES THEREOF
    Publication number: 20170158669
    Abstract: Provided herein are compounds of the formulas (I) and (II): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of Retinoic Acid Receptor-Related Orphan Receptor regulated diseases and disorders.
    Type: Application
    Filed: July 24, 2015
    Publication date: June 8, 2017
    Inventors: Anderson Gaweco, Jefferson Tilley, James Blinn
  • ROR modulators and their uses
    Patent number: 9447069
    Abstract: The invention relates to ROR modulators; compositions comprising an effective amount of a ROR modulator; and methods for treating or preventing diseases associated with ROR.
    Type: Grant
    Filed: April 30, 2013
    Date of Patent: September 20, 2016
    Assignee: INNOV17 LLC
    Inventors: Anderson Gaweco, Jefferson W. Tilley, John Walker, Samantha Palmer, James Blinn
  • ROR MODULATORS AND THEIR USES
    Publication number: 20160130231
    Abstract: The invention relates to ROR modulators; compositions comprising an effective amount of a ROR modulator; and methods for treating or preventing diseases associated with ROR.
    Type: Application
    Filed: January 5, 2016
    Publication date: May 12, 2016
    Inventors: Anderson Gaweco, Jefferson W. Tilley, John Walker, Samantha Palmer, James Blinn
  • ROR modulators and their uses
    Patent number: 9321750
    Abstract: The invention relates to ROR modulators; compositions comprising an effective amount of a ROR modulator; and methods for treating or preventing diseases associated with ROR. The invention is based in part on the discovery of ROR modulators which interact with RORa and/or RORy and thereby inhibit or induce RORa and/or RORy-activity, and RORa- and/or RORy-regulated target gene and protein expression.
    Type: Grant
    Filed: April 22, 2013
    Date of Patent: April 26, 2016
    Assignee: INNOV17 LLC
    Inventors: Anderson Gaweco, Jefferson W. Tilley, John Walker, Samantha Palmer, James Blinn
  • SULFONAMIDE RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTOR MODULATORS AND USES THEREOF
    Publication number: 20160024056
    Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of Retinoic Acid Receptor-Related Orphan Receptor regulated diseases and disorders.
    Type: Application
    Filed: July 24, 2015
    Publication date: January 28, 2016
    Inventors: Anderson Gaweco, Jefferson Tilley, James Blinn
  • INDAZOLE RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTOR MODULATORS AND USES THEREOF
    Publication number: 20160024057
    Abstract: Provided herein are compounds of the formulas (I) and (II): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of Retinoic Acid Receptor-Related Orphan Receptor regulated diseases and disorders.
    Type: Application
    Filed: July 24, 2015
    Publication date: January 28, 2016
    Inventors: Anderson Gaweco, Jefferson Tilley, James Blinn
  • BENZIMIDAZOLE RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTOR MODULATORS AND USES THEREOF
    Publication number: 20160024052
    Abstract: Provided herein are compounds of the formulas (I) and (II): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of Retinoic Acid Receptor-Related Orphan Receptor regulated diseases and disorders.
    Type: Application
    Filed: July 24, 2015
    Publication date: January 28, 2016
    Inventors: Anderson Gaweco, Jefferson Tilley, James Blinn
  • AZAINDOLE RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTOR MODULATORS AND USES THEREOF
    Publication number: 20160024086
    Abstract: Provided herein are compounds of the formulas (I) and (II): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of Retinoic Acid Receptor-Related Orphan Receptor regulated diseases and disorders.
    Type: Application
    Filed: July 24, 2015
    Publication date: January 28, 2016
    Inventors: Anderson Gaweco, Jefferson Tilley, James Blinn
  • ROR MODULATORS AND THEIR USES
    Publication number: 20150284366
    Abstract: The invention relates to ROR modulators; compositions comprising an effective amount of a ROR modulator; and methods for treating or preventing diseases associated with ROR. The invention is based in part on the discovery of ROR modulators which interact with RORa and/or RORy and thereby inhibit or induce RORa and/or RORy-activity, and RORa- and/or RORy-regulated target gene and protein expression.
    Type: Application
    Filed: April 22, 2013
    Publication date: October 8, 2015
    Inventors: Anderson GAWECO, Jefferson TILLEY, John WALKER, Samantha PALMER, James BLINN
  • RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTOR MODULATORS AND USES THEREOF
    Publication number: 20150252022
    Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of Retinoic Acid Receptor-Related Orphan Receptor regulated diseases and disorders.
    Type: Application
    Filed: March 9, 2015
    Publication date: September 10, 2015
    Inventors: Anderson Gaweco, Jefferson Tilley, James Blinn
  • RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTOR MODULATORS AND USES THEREOF
    Publication number: 20150252051
    Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of Retinoic Acid Receptor-Related Orphan Receptor regulated diseases and disorders.
    Type: Application
    Filed: March 9, 2015
    Publication date: September 10, 2015
    Inventors: Anderson Gaweco, Jefferson Tilley, James Blinn
  • ROR MODULATORS AND THEIR USES
    Publication number: 20150099779
    Abstract: The invention relates to ROR modulators; compositions comprising an effective amount of a ROR modulator; and methods for treating or preventing diseases associated with ROR.
    Type: Application
    Filed: April 30, 2013
    Publication date: April 9, 2015
    Inventors: Anderson Gaweco, Jefferson W. Tilley, John Walker, Samantha Palmer, James Blinn
  • ROR MODULATORS AND THEIR USES
    Publication number: 20150073016
    Abstract: The invention relates to ROR modulators; compositions comprising an effective amount of a ROR modulator; and methods for treating or preventing diseases associated with ROR.
    Type: Application
    Filed: April 30, 2013
    Publication date: March 12, 2015
    Inventors: Anderson GAWECO, Jefferson TILLEY, John WALKER, Samantha PALMER, James BLINN