Patents by Inventor James Chian Ming Wang

James Chian Ming Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODULATED PROGRAMMED DEATH LIGAND-1
    Publication number: 20120251514
    Abstract: The invention provides nucleic acids comprising a nucleotide sequence encoding programmed death ligand-1 (PD-L1) and a nucleotide sequence encoding a fusion protein comprising thymidylate kinase (TMPK) or a variant thereof and a cell surface marker or a variant thereof. Recombinant expression vectors, host cells, populations of cells, pharmaceutical compositions, and kits relating to the nucleic acids are disclosed. Methods of treating or preventing a disease in a host and methods of suppressing an immune system in a host are also disclosed.
    Type: Application
    Filed: November 12, 2010
    Publication date: October 4, 2012
    Applicants: University Health Network, The United States of America, as rep. by the Sec. Department of Health and Human Services
    Inventors: Daniel Fowler, Shoba Amarnath, Jeffrey Medin, James Chian Ming Wang