Abstract: An antiseptic soap dispenser has a dispensing system (28) which includes a pressure actuated platen (32) and a moveable roller (94) for dispensing soap from a replaceable container (12). A dispensing tube (10) with an integral self-sealing valve (40) at a downstream end is connected to a neck (20) of the container. Hand pressure on the platen compresses a upstream end of the dispensing tube between the platen and the roller. With increasing pressure, the roller moves progressively down the tube to dispense soap through the valve. A volume regulator (111) controls the amount of soap dispensed. The platen returns quickly to its at-rest position once the pressure is removed, avoiding complete compression of the pathway by the roller. This minimizes air ingress, and resultant contamination of the soap. Optionally, a filtered vent (14) in a wall (22) of the container allows filtered air to enter the container in place of the soap dispensed.