Abstract: Compounds that inhibit KRas G12D. In particular, compounds that inhibit the activity of KRas G12D, pharmaceutical compositions comprising the compounds and methods of use therefor, and in particular, methods of treating cancer. The compounds have a general structure represented by Formula (I): or a pharmaceutically acceptable salt thereof.

Abstract: The present disclosure relates to a bee hive carrier and transport means comprising a frame having bee hive supports each capable of supporting a plurality of bee hives in closely adjacent relationship to each other; said bee hive supports being moveable relative to each other and disposable in closely adjacent relationship to each other whereby a large number of bee hives may be supported in compact relationship to each other on said frame, some of said bee hive supports being moveable relative to other bee hive supports so as to provide for the moving of the bee hives on one of said supports away from the bee hives on an adjacent support in order to provide space between the supports and respective hives for the bees to work and for manual servicing of the hives; the disclosure also relating to an enclosed body for containing and enclosing the aforementioned supports and hives thereon; the enclosure having closeable bee access openings in the sides thereof to provide access for bees to enter hives inside th