Abstract: The present invention relates to compounds useful as inhibitors of indoleamine 2,3-dioxygenase (IDO). The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications. The compounds of this invention have formula I-A: wherein the variables are as defined herein.

Abstract: The present invention relates to compounds useful as inhibitors of indoleamine 2,3-dioxygenase (IDO). The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications. The compounds of this invention have formula I-A: wherein the variables are as defined herein.

Abstract: A flange bolt cutter for separating two connected flanges. The flange bolt cutter contains a circular saw blade connected to an flange mount which can be vertically adjusted relative to the flange mount and/or includes two arms which can be pivotally adjusted relative to each other.

Abstract: A flange bolt cutter for separating two connected flanges. The flange bolt cutter contains a circular saw blade connected to an flange mount which can be vertically adjusted relative to the flange mount and/or includes two arms which can be pivotally adjusted relative to each other.

Abstract: The present invention relates to compounds useful as inhibitors of indoleamine 2,3-dioxygenase (IDO). The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications. The compounds of this invention have formula I-A: wherein the variables are as defined herein.

Abstract: Systems and methods for collection and automatic analysis of opinions of media are provided. A representative method includes: receiving, from a user, media for review; automatically distributing the media to a pool of reviewers based on reviewer profiles; receiving, from the reviewers, information corresponding to opinions pertaining to the media; automatically generating a report based, at least in part, on the information received from the reviewers; and providing the report to the user.

Abstract: A switching regulator (2-5) supplies a controllable stable average current to a load (1), such as series-connected light emitting diodes. A regulator controller (2) includes a hysteretic comparator (12, 30) which controls a switch in the form of a transistor (15) for switching current into an inductor (3). The comparator (12) has upper and lower thresholds. A first circuit comprising a fast current monitor (6) supplies a first signal to the comparator representing the instantaneous current in the inductor (3). A second circuit (36, 37, 41, and 42) supplies a second signal to the comparator representing an error between a desired regulator output and an actual regulator output.

Abstract: As set forth herein, methods and systems for automatic grouping of individual print jobs into a common job at a multifunction device. Received jobs stored in a job processing queue are analyzed to determine the filenames, submission times, and other related identification data. Those jobs sharing a common naming convention, submission time interval, or other common identifiers, are automatically grouped into a single, common job. Upon login, the user is able to approve or disapprove the grouping. For an approved grouping, the user is able to select finishing options via the user interface of the multifunction device to be applied to the common job. The common job, in which the finishing options have been propagated through each formerly individual job, is then output as if it were a single job by the multifunction device.

Abstract: A creased and perforated printable sheet is used with methods to produce framed printed pictures. The sheet comprises a flat sheet of media having a first side, a second side opposite the first side, and sheet edges between the first side and the second side. Perforations and creases are included within the first side and the second side of the sheet of media, and, when folded, produce a three-dimensional effect. The creases and the perforations define a picture region on the first side of the sheet of media and picture frame regions on the second side of the sheet of media. The picture region and the picture frame regions comprise surfaces having a material composition and texture that accepts and maintains marking material applied by printing devices. The perforations also define removable discard regions and tab slots. The removable discard regions are positioned only between the picture frame regions and the sheet edges.

Abstract: An oral composition for oral cleansing, breath freshening, and anti-microbial benefits includes Magnolia Bark Extract in combination with a surface active agent. The effectiveness of Magnolia Bark Extract in inhibiting biofilm formation in the oral cavity is increased by a synergistic combination of the Magnolia Bark Extract with a surface active agent in an oral cavity delivery agent, such as chewing gum, a confectionary, a lozenge, a compressed tablet, and an edible film.

Abstract: An air treatment system includes features for maximizing efficiency and effectiveness. In one embodiment, a sensor air passage utilizes a low pressure region created by the blower to draw air through the passage. In another embodiment, a filter frame includes a plurality of connectors formed integrally with the filter frame. In another embodiment, a screen is positioned adjacent to the blower intake. The screen includes a plurality of angled strands oriented in a particular direction. In another embodiment, a remote control holder is formed integrally with the housing. In another embodiment, a gasket is positioned between the blower and the housing, forming a seal between the blower and the housing.

Abstract: The present invention is related to weapons systems. In particular, the present invention is directed to accessory attachment systems for rifles and small arms weapons that enable attached accessory devices to draw power from a central power source and communicate with the user and/or other devices.

Abstract: A switching regulator (2-5) supplies a controllable stable average current to a load (1), such as series-connected light emitting diodes. A regulator controller (2) includes a hysteretic comparator (12, 30) which controls a switch in the form of a transistor (15) for switching current into an inductor (3). The comparator (12) has upper and lower thresholds. A first circuit comprising a fast current monitor (6) supplies a first signal to the comparator representing the instantaneous current in the inductor (3). A second circuit (36, 37, 41, and 42) supplies a second signal to the comparator representing an error between a desired regulator output and an actual regulator output.

Abstract: The present invention is related to weapons systems. In particular, the present invention is directed to accessory attachment systems for rifles and small arms weapons that enable attached accessory devices to draw power from a central power source and communicate with the user and/or other devices. The present invention embodies firearm systems comprising at least one mounting rail comprising at least one power connection, at least one power source, at least one rail accessory comprising a rail grabber or mount, wherein the at least one rail accessory receives electrical power from the power source.

Abstract: The present invention is related to weapons systems. In particular, the present invention is directed to accessory attachment systems for rifles and small arms weapons that enable attached accessory devices to draw power from a central power source and communicate with the user and/or other devices.

Abstract: The present invention is related to weapons systems. In particular, the present invention is directed to accessory attachment systems for rifles and small arms weapons that enable attached accessory devices to draw power from a central power source and communicate with the user and/or other devices.

Abstract: The present invention is related to weapons systems. In particular, the present invention is directed to accessory attachment systems for rifles and small arms weapons that enable attached accessory devices to draw power from a central power source and communicate with the user and/or other devices.

Abstract: The present invention is related to weapons systems. In particular, the present invention is directed to accessory attachment systems for rifles and small arms weapons that enable attached accessory devices to draw power from a central power source and communicate with the user and/or other devices. The present invention embodies firearm systems comprising at least one mounting rail comprising at least one power connection, at least one power source, at least one rail accessory, wherein the at least one rail accessory receives electrical power from the power source.

Abstract: An oral composition for oral cleansing, breath freshening, and anti-microbial benefits includes Magnolia Bark Extract in combination with a surface active agent. The effectiveness of Magnolia Bark Extract in inhibiting biofilm formation in the oral cavity is increased by a synergistic combination of the Magnolia Bark Extract with a surface active agent in an oral cavity delivery agent, such as chewing gum, a confectionary, a lozenge, a compressed tablet, and an edible film.