Patents by Inventor James Donegan
James Donegan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20060014156Abstract: This invention provides novel compositions and processes for analyte detection, quantification and amplification. Nucleic acid arrays and libraries of analytes are usefully incorporated into such compositions and processes. Universal detection elements, signaling entities and the like are employed to detect and if necessary or desirable, to quantify analytes. Amplification of target analytes are also provided by the compositions and processes of this invention.Type: ApplicationFiled: July 29, 2004Publication date: January 19, 2006Applicant: Enzo Life Sciences, Inc.Inventors: Elazar Rabbani, Jannis Stavrianopoulos, James Donegan, Jack Coleman
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Publication number: 20050277112Abstract: This invention provides novel processes for therapeutic applications, including the treatment of subjects carrying infectious agents or having impaired autoimmunity or impaired immune condition. The therapeutic applications disclosed herein are also directed at the treatment of cancerous subjects with malignant tumors containing cancerous cells or malignant or cancerous cells. Vaccination processes for preventing infections in subjects are also provided. The novel processes comprise introducing into or adminstering to a subject one or more antigens, or trained or adopted immune cells. These antigens or immune cells are capable of establishing or increasing at least one first specific immune response and decreasing at least one second specific immune response. Such responses include components, such as cellular immune reaction elements, humoral immune reaction elements and cytokines, the latter also encompassing interferons and lymphokines. Useful compositions are also provided by this invention.Type: ApplicationFiled: December 8, 2003Publication date: December 15, 2005Applicant: Enzo Therapeutics, Inc., c/o Enzo Biochem, Inc.Inventors: Yaron Ilan, Elazar Rabbani, Dean Engelhardt, Israel Gotsman, James Donegan
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Publication number: 20050260560Abstract: This invention provides novel processes for therapeutic applications, including the treatment of subjects carrying infectious agents or having impaired autoimmunity or impaired immune condition. The therapeutic applications disclosed herein are also directed at the treatment of cancerous subjects with malignant tumors containing cancerous cells or malignant or cancerous cells. Vaccination processes for preventing infections in subjects are also provided. The novel processes comprise introducing into or adminstering to a subject one or more antigens, or trained or adopted immurie cells. These antigens or immune cells are capable of establishing or increasing at least one first specific immune response and decreasing at least one second specific immune response. Such responses include components, such as cellular immune reaction elements, humoral immune reaction elements and cytokines, the latter also encompassing interferons and lymphokines. Useful compositions are also provided by this invention.Type: ApplicationFiled: December 8, 2003Publication date: November 24, 2005Applicant: Enzo Therapeutics, Inc., c/o Enzo Biochem, Inc.Inventors: Yaron Ilan, Elazar Rabbani, Dean Engelhardt, Isarel Gotsman, James Donegan
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Publication number: 20050260226Abstract: This invention provides novel processes for therapeutic applications, including the treatment of subjects carrying infectious agents or having impaired autoimmunity or impaired immune condition. The therapeutic applications disclosed herein are also directed at the treatment of cancerous subjects with malignant tumors containing cancerous cells or malignant or cancerous cells. Vaccination processes for preventing infections in subjects are also provided. The novel processes comprise introducing into or adminstering to a subject one or more antigens, or trained or adopted immune cells. These antigens or immune cells are capable of establishing or increasing at least one first specific immune response and decreasing at least one second specific immune response. Such responses include components, such as cellular immune reaction elements, humoral immune reaction elements and cytokines, the latter also encompassing interferons and lymphokines. Useful compositions are also provided by this invention.Type: ApplicationFiled: December 8, 2003Publication date: November 24, 2005Applicant: Enzo Therapeutics, Inc., c/o Enzo Biochem, Inc.Inventors: Yaron Ilan, Elazar Rabbani, Dean Engelhardt, Israel Gotsman, James Donegan
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Publication number: 20050260227Abstract: This invention provides novel processes for therapeutic applications, including the treatment of subjects carrying infectious agents or having impaired autoimmunity or impaired immune condition. The therapeutic applications disclosed herein are also directed at the treatment of cancerous subjects with malignant tumors containing cancerous cells or malignant or cancerous cells. Vaccination processes for preventing infections in subjects are also provided. The novel processes comprise introducing into or adminstering to a subject one or more antigens, or trained or adopted immune cells. These antigens or immune cells are capable of establishing or increasing at least one first specific immune response and decreasing at least one second specific immune response. Such responses include components, such as cellular immune reaction elements, humoral immune reaction elements and cytokines, the latter also encompassing interferons and lymphokines. Useful compositions are also provided by this invention.Type: ApplicationFiled: December 8, 2003Publication date: November 24, 2005Applicant: Enzo Therapeutics, Inc., c/o Enzo Biochem, Inc.Inventors: Yaron Ilan, Elazar Rabbani, Dean Engelhardt, Israel Gotsman, James Donegan
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Publication number: 20050260573Abstract: This invention provides novel processes for amplifying nucleic acid sequences of interest, including linear and non-linear amplification. In linear amplification, a single initial primer or nucleic acid construct is utilized to carry out the amplification process. In non-linear amplification, a first initial primer or nucleic acid construct is employed with a subsequent initial primer or nucleic acid construct. In other non-linear amplification processes provided by this invention, a first initial primer or nucleic acid construct is deployed with a second initial primer or nucleic acid construct to amplify the specific nucleic acid sequence of interest and its complement that are provided. A singular primer or a singular nucleic acid construct capable of non-linear amplification can also be used to carry out non-linear amplification in accordance with this invention.Type: ApplicationFiled: November 22, 2002Publication date: November 24, 2005Inventors: Elazar Rabbani, Jannis Stavrianopoulos, James Donegan, Jack Coleman, Marleen Walner
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Publication number: 20050255454Abstract: This invention provides novel processes for therapeutic applications, including the treatment of subjects carrying infectious agents or having impaired autoimmunity or impaired immune condition. The therapeutic applications disclosed herein are also directed at the treatment of cancerous subjects with malignant tumors containing cancerous cells or malignant or cancerous cells. Vaccination processes for preventing infections in subjects are also provided. The novel processes comprise introducing into or adminstering to a subject one or more antigens, or trained or adopted immune cells. These antigens or immune cells are capable of establishing or increasing at least one first specific immune response and decreasing at least one second specific immune response. Such responses include components, such as cellular immune reaction elements, humoral immune reaction elements and cytokines, the latter also encompassing interferons and lymphokines. Useful compositions are also provided by this invention.Type: ApplicationFiled: December 8, 2003Publication date: November 17, 2005Applicant: Enzo Therapeutics, Inc.Inventors: Yaron Ilan, Elazar Rabbani, Dean Engelhardt, Israel Gotsman, James Donegan
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Publication number: 20050233343Abstract: This invention provides novel compositions and processes for analyte detection, quantification and amplification. Nucleic acid arrays and libraries of analytes are usefully incorporated into such compositions and processes. Universal detection elements, signaling entities and the like are employed to detect and if necessary or desirable, to quantify analytes. Amplification of target analytes are also provided by the compositions and processes of this invention.Type: ApplicationFiled: July 27, 2004Publication date: October 20, 2005Applicant: Enzo Life Sciences Inc.,Inventors: Elazar Rabbani, Jannis Stavrianopoulos, James Donegan, Jack Coleman
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Publication number: 20050214784Abstract: This invention provides novel compositions and processes for analyte detection, quantification and amplification. Nucleic acid arrays and libraries of analytes are usefully incorporated into such compositions and processes. Universal detection elements, signaling entities and the like are employed to detect and if necessary or desirable, to quantify analytes. Amplification of target analytes are also provided by the compositions and processes of this invention.Type: ApplicationFiled: July 29, 2004Publication date: September 29, 2005Applicant: Enzo Life Sciences, Inc.Inventors: Elazar Rabbani, Jannis Stavrianopoulos, James Donegan, Jack Coleman
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Publication number: 20050202456Abstract: This invention provides novel compositions and processes for analyte detection, quantification and amplification. Nucleic acid arrays and libraries of analytes are usefully incorporated into such compositions and processes. Universal detection elements, signaling entities and the like are employed to detect and if necessary or desirable, to quantify analytes. Amplification of target analytes are also provided by the compositions and processes of this invention.Type: ApplicationFiled: July 29, 2004Publication date: September 15, 2005Applicant: Enzo Life Sciences, Inc., c/o Enzo Biochem, Inc.Inventors: Elazar Rabbani, Jannis Stavrianopoulos, James Donegan, Jack Coleman
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Publication number: 20050202455Abstract: This invention provides novel compositions and processes for analyte detection, quantification and amplification. Nucleic acid arrays and libraries of analytes are usefully incorporated into such compositions and processes. Universal detection elements, signaling entities and the like are employed to detect and if necessary or desirable, to quantify analytes. Amplification of target analytes are also provided by the compositions and processes of this invention.Type: ApplicationFiled: July 29, 2004Publication date: September 15, 2005Applicant: Enzo Life Sciences, Inc.Inventors: Elazar Rabbani, Jannis Stavrianopoulos, James Donegan, Jack Coleman
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Publication number: 20050170370Abstract: This invention provides novel compositions and processes for analyte detection, quantification and amplification. Nucleic acid arrays and libraries of analytes are usefully incorporated into such compositions and processes. Universal detection elements, signaling entities and the like are employed to detect and if necessary or desirable, to quantify analytes. Amplification of target analytes are also provided by the compositions and processes of this invention.Type: ApplicationFiled: July 29, 2004Publication date: August 4, 2005Applicant: Enzo Life Sciences, Inc., c/o Enzo Biochem, Inc.Inventors: Elazar Rabbani, Jannis Stavrianopqulos, James Donegan, Jack Coleman
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Publication number: 20050147586Abstract: This invention provides novel processes for therapeutic applications, including the treatment of subjects carrying infectious agents or having impaired autoimmunity or impaired immune condition. The therapeutic applications disclosed herein are also directed at the treatment of cancerous subjects with malignant tumors containing cancerous cells or malignant or cancerous cells. Vaccination processes for preventing infections in subjects are also provided. The novel processes comprise introducing into or adminstering to a subject one or more antigens, or trained or adopted immune cells. These antigens or immune cells are capable of establishing or increasing at least one first specific immune response and decreasing at least one second specific immune response. Such responses include components, such as cellular immune reaction elements, humoral immune reaction elements and cytokines, the latter also encompassing interferons and lymphokines. Useful compositions are also provided by this invention.Type: ApplicationFiled: December 8, 2003Publication date: July 7, 2005Applicant: Enzo TherapeuticsInventors: Yaron Ilan, Elazar Rabbani, Dean Engelhardt, Israel Gotsman, James Donegan
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Publication number: 20050137388Abstract: This invention provides for compositions for use in real time nucleic acid detection processes. Such real time nucleic acid detection processes are carried out with energy transfer elements attached to nucleic acid primers, nucleotides, nucleic acid probes or nucleic acid binding agents. Real time nucleic acid detection allows for the qualitative or quantitative detection or determination of single-stranded or double-stranded nucleic acids of interest in a sample. Other processes are provided by this invention including processes for removing a portion of a homopolymeric sequence, e.g., poly A sequence or tail, from an analyte or library of analytes. Compositions useful in carrying out such removal processes are also described and provided.Type: ApplicationFiled: March 12, 2002Publication date: June 23, 2005Inventors: Elazar Rabbani, Jannis Stavrianopoulos, James Donegan, Jack Coleman, Dakai Liu
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Publication number: 20050136074Abstract: This invention provides novel processes for therapeutic applications, including the treatment of subjects carrying infectious agents or having impaired autoimmunity or impaired immune condition. The therapeutic applications disclosed herein are also directed at the treatment of cancerous subjects with malignant tumors containing cancerous cells or malignant or cancerous cells. Vaccination processes for preventing infections in subjects are also provided. The novel processes comprise introducing into or adminstering to a subject one or more antigens, or trained or adopted immune cells. These antigens or immune cells are capable of establishing or increasing at least one first specific immune response and decreasing at least one second specific immune response. Such responses include components, such as cellular immune reaction elements, humoral immune reaction elements and cytokines, the latter also encompassing interferons and lymphokines. Useful compositions are also provided by this invention.Type: ApplicationFiled: December 8, 2003Publication date: June 23, 2005Applicant: Enzo Therapeutics, Inc., c/o Enzo Biochem, Inc.Inventors: Yaron Ilan, Elazar Rabbani, Dean Engelhardt, Israel Gotsman, James Donegan
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Publication number: 20050123926Abstract: This invention provides inter alia an in vitro process for producing multiple specific nucleic acid copies in which the copies are produced under isostatic conditions, e.g., temperature, buffer and ionic strength, and independently of any requirement for introducing an intermediate structure for producing the copies. In other aspects, the invention provides in vitro processes for producing multiple specific nucleic acid copies in which the products are substantially free of any primer-coded sequences, such sequences having been substantially or all removed from the product to regenerate a primer binding site, thereby allowing new priming events to occur and multiple nucleic acid copies to be produced. This invention further provides a promoter-independent non-naturally occurring nucleic acid construct that produces a nucleic acid copy or copies without using or relying on any gene product that may be coded by the nucleic acid construct.Type: ApplicationFiled: November 14, 2003Publication date: June 9, 2005Applicant: Enzo Diagnostics, Inc.,Inventors: Dean Engelhardt, Jannis Stavrianopoulos, Elazar Rabbani, James Donegan
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Publication number: 20050123927Abstract: This invention provides inter alia an in vitro process for producing multiple specific nucleic acid copies in which the copies are produced under isostatic conditions, e.g., temperature, buffer and ionic strength, and independently of any requirement for introducing an intermediate structure for producing the copies. In other aspects, the invention provides in vitro processes for producing multiple specific nucleic acid copies in which the products are substantially free of any primer-coded sequences, such sequences having been substantially or all removed from the product to regenerate a primer binding site, thereby allowing new priming events to occur and multiple nucleic acid copies to be produced. This invention further provides a promoter-independent non-naturally occurring nucleic acid construct that produces a nucleic acid copy or copies without using or relying on any gene product that may be coded by the nucleic acid construct.Type: ApplicationFiled: November 19, 2003Publication date: June 9, 2005Applicant: Enzo Diagnostics, Inc.Inventors: Dean Engelhardt, Jannis Stavrianopoulos, Elazar Rabbani, James Donegan
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Publication number: 20050118196Abstract: This invention provides novel processes for therapeutic applications, including the treatment of subjects carrying infectious agents or having impaired autoimmunity or impaired immune condition. The therapeutic applications disclosed herein are also directed at the treatment of cancerous subjects with malignant tumors containing cancerous cells or malignant or cancerous cells. Vaccination processes for preventing infections in subjects are also provided. The novel processes comprise introducing into or adminstering to a subject one or more antigens, or trained or adopted immune cells. These antigens or immune cells are capable of establishing or increasing at least one first specific immune response and decreasing at least one second specific immune response. Such responses include components, such as cellular immune reaction elements, humoral immune reaction elements and cytokines, the latter also encompassing interferons and lymphokines. Useful compositions are also provided by this invention.Type: ApplicationFiled: December 8, 2003Publication date: June 2, 2005Applicant: Enzo Therapeutics, Inc. c/o Enzo Biochem, Inc.Inventors: Yaron Ilan, Elazar Rabbani, Dean Engelhardt, Israel Gotsman, James Donegan
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Publication number: 20050009077Abstract: This invention provides novel compositions and processes for analyte detection, quantification and amplification. Nucleic acid arrays and libraries of analytes are usefully incorporated into such compositions and processes. Universal detection elements, signaling entities and the like are employed to detect and if necessary or desirable, to quantify analytes. Amplification of target analytes are also provided by the compositions and processes of this invention.Type: ApplicationFiled: July 27, 2004Publication date: January 13, 2005Applicant: Enzo Life Sciences Inc.,Inventors: Flazar Rabbani, Jannis Stavrianopoulos, James Donegan, Jack Coleman
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Patent number: 4144834Abstract: A thaw-indicating device that is visibly positioned in a package of frozen food so to warn a consumer if the food item has ever been subjected to being thawed, and thus being spoiled even if refrozen subsequently; the device consisting of a transparent plastic capsule having a sealed singular compartment in one end of which there is a colorless, clear, frozen ice and in the other end of which there is a powdered dye that is soluble in water, so that if the ice melts into water due to thawing temperatures the entire interior of the capsule is visibly colored.Type: GrantFiled: December 27, 1976Date of Patent: March 20, 1979Inventor: James Donegan