Abstract: A computer includes a plurality of activity modules in multiple virtual machines. An activity module performs an activity, such as malware detection, in a virtual machine. A monitoring module receives virtualized infrastructure information of the computer comprising a hardware configuration of the computer and a virtual machine configuration of the computer. A scheduling module determines, based on the virtualized infrastructure information, scheduling instructions for an activity module. A supervisor communication module causes the activity module to execute based on the scheduling instructions. The scheduling instructions minimize hardware resource conflicts between the activity module and the other activity modules of the computer.