Patents by Inventor James E. Geever

James E. Geever has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4820804
    Abstract: New hypocalcaemic peptides are disclosed of the formula ##STR1## wherein X represents H for the replacement of the N alpha amino group or acyl groups for the acylation of the N alpha amino group, the N-alpha amino group. The acyl groups are carboxylic acids especially formic, acetic, propionic, buteric, valeric, hexanoic, heptanoic, octanoic, and nonanoic acids or their respective isomers, L-lactic acid and the half amides of malonic, succinic, glutaric and adipic acids. Y is L-valine, glycine, L-methionine, L-alanine, L-leucine or L-isoleucine.
    Type: Grant
    Filed: April 21, 1987
    Date of Patent: April 11, 1989
    Assignee: Rorer Pharmaceutical Corporation
    Inventors: Ronald C. Orlowski, Jay K. Seyler, James E. Geever, Everett Flanigan
  • Patent number: 4732969
    Abstract: New peptides are disclosed which have biological activity of the same type as known calcitonins and which do not have a leucine in position 19 or a glutamine in position 20. Both amino acids are omitted. Also resin peptides are disclosed which may be converted to peptides having such biological activity; and processes for producing said resin peptides and said calcitonin peptides.
    Type: Grant
    Filed: May 5, 1986
    Date of Patent: March 22, 1988
    Assignee: Armour Pharmaceutical Corporation
    Inventors: Ronald C. Orlowski, Jay K. Seyler, James E. Geever
  • Patent number: 4659804
    Abstract: New peptides are disclosed which have biological activity of the same type as known calcitonins and which do not have a disulfide bond connecting the cysteines at positions one and seven. Also resin peptides are disclosed which may be converted to peptides having such biological activity; and processes for producing said resin peptides and said calcitonin partially protected peptides.
    Type: Grant
    Filed: November 1, 1984
    Date of Patent: April 21, 1987
    Assignee: Armour Pharmaceutical Company
    Inventors: Ronald C. Orlowski, Jay K. Seyler, Robert L. Colescott, Glenn L. Stahl, Takashi Enkoji, James E. Geever, Everett Flanigan