Patents by Inventor James E. Strickler

James E. Strickler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthetic protease substrates, assay methods using such substrates and kits for practicing the assay
    Patent number: 8697376
    Abstract: Synthetic protease substrates and methods which facilitate the identification of substrates of a protease, particularly ubiquitin, ubiquitin-like, or proteasome protein are provided.
    Type: Grant
    Filed: February 3, 2011
    Date of Patent: April 15, 2014
    Assignee: Lifesensors, INc.
    Inventors: Tauseef R. Butt, Joseph Manimala, Mabel A. Cejas, James E. Strickler, William Kingsbury, Jian Wu
  • SYNTHETIC PROTEASE SUBSTRATES, ASSAY METHODS USING SUCH SUBSTRATES AND KITS FOR PRACTICING THE ASSAY
    Publication number: 20110319293
    Abstract: Synthetic protease substrates and methods which facilitate the identification of substrates of a protease, particularly ubiquitin, ubiquitin-like, or proteasome protein are provided.
    Type: Application
    Filed: February 3, 2011
    Publication date: December 29, 2011
    Inventors: Tauseef R. Butt, Joseph Manimala, Mabel A. Cejas, James E. Strickler, William Kingsbury, Jian Wu
  • Antibodies produced against cytokine suppressive anti-inflammatory drug binding proteins
    Patent number: 6361773
    Abstract: This invention relates to drug binding proteins, to genes encoding same and to assays and methods for screening pharmaceuticals. More specifically, this invention relates to a Cytokine Suppressive Anti-Inflammatory Drug (CSAID) binding protein, to a gene encoding same and to assays and screens useful in the evaluation and characterization of drugs of this pharmacologic class.
    Type: Grant
    Filed: October 1, 1997
    Date of Patent: March 26, 2002
    Assignee: SmithKline Beecham Corporation
    Inventors: John C. Lee, Jerry L. Adams, Timothy F. Gallagher, David W. Green, John Richard Heys, Peter C. McDonnell, Dean E. McNulty, Peter R. Young, James E. Strickler
  • Polynucleotides encoding cytokine suppressive anti-inflammatory drug binding proteins
    Patent number: 5955366
    Abstract: This invention relates to drug binding proteins, to genes encoding same and to assays and methods for screening pharmaceuticals. More specifically, this invention relates to a Cytokine Suppressive Anti-Inflammatory Drug (CSAID) binding protein, to a gene encoding same and to assays and screens useful in the evaluation and characterization of drugs of this pharmacologic class.
    Type: Grant
    Filed: October 14, 1997
    Date of Patent: September 21, 1999
    Assignee: SmithKline Beecham Corporation
    Inventors: John C. Lee, Jerry L. Adams, Timothy F. Gallagher, David W. Green, John Richard Heys, Peter C. McDonnell, Dean E. McNulty, James E. Strickler, Peter R. Young
  • Screening methods using cytokine suppressive anti-inflammatory drug (CSAID) binding proteins
    Patent number: 5871934
    Abstract: This invention relates to methods of screening for pharmaceuticals using Cytokine Suppressive Anti-Inflammatory Drug (CSAID) binding proteins.
    Type: Grant
    Filed: April 15, 1996
    Date of Patent: February 16, 1999
    Assignee: SmithKline Beecham Corporation
    Inventors: John Cheung-Lun Lee, Jerry Leroy Adams, Timothy Francis Gallagher, David W. Green, John Richard Heys, Peter Colon McDonnell, Dean Edward McNulty, James E. Strickler, Peter Ronald Young
  • Purified human CSF-1
    Patent number: 5792450
    Abstract: The present invention relates to the purification of proteins, to the products of such purification, and to DNA probes constructed therefrom. More specifically, the invention relates to the purification and sequencing of murine and human colony stimulating factor-1 (CSF-1).
    Type: Grant
    Filed: March 13, 1995
    Date of Patent: August 11, 1998
    Assignees: Chiron Corporation, Albert Einstein College of Medicine
    Inventors: Kenneth J. Wilson, E. Richard Stanley, Albert Boosman, Mary Kim Warren, James E. Strickler, Judit Csejtey
  • Cytokine suppressive anit-inflammatory drug binding proteins
    Patent number: 5783664
    Abstract: This invention relates to drug binding proteins, to genes encoding same and to assays and methods for screening pharmaceuticals. More specifically, this invention relates to a Cytokine Suppressive Anti-Inflammatory Drug (CSAID) binding protein, to a gene encoding same and to assays and screens useful in the evaluation and characterization of drugs of this pharmacologic class.
    Type: Grant
    Filed: May 31, 1994
    Date of Patent: July 21, 1998
    Assignee: SmithKline Beecham Corporation
    Inventors: John C. Lee, Jerry L. Adams, Timothy F. Gallagher, David W. Green, John Richard Heys, Peter C. McDonnell, Dean E. McNulty, James E. Strickler, Peter R. Young
  • Oligonucleotides comprising a region of a cytokine suppressive anti-inflammatory drug binding protein
    Patent number: 5777097
    Abstract: This invention relates to drug binding proteins, to genes encoding same and to assays and methods for screening pharmaceuticals. More specifically, this invention relates to a Cytokine Suppressive Anti-Inflammatory Drug (CSAID) binding protein, to a gene encoding same and to assays and screens useful in the evaluation and characterization of drugs of this pharmacologic class.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: July 7, 1998
    Assignee: SmithKline Beecham Corporation
    Inventors: John C. Lee, Jerry L. Adams, Timothy F. Gallagher, David W. Green, John Richard Heys, Peter C. McDonnell, Dean E. McNulty, Peter R. Young, James E. Strickler
  • Protein protease inhibitors from streptomyces
    Patent number: 5498529
    Abstract: This invention relates to a process for producing a heterologous polypeptide in Streptomyces which involves transforming a Streptomyces organism with a recombinant DNA molecule comprising an LEP-10 of LTl sequence selected from the group consisting of a sequence encoding a gene expression unit, a promoter sequence or an export control encoding sequence each operatively linked to a heterologous coding sequence and then culturing the transformed Streptomyces such that the heterologous polypeptide is expressed.
    Type: Grant
    Filed: December 3, 1993
    Date of Patent: March 12, 1996
    Assignee: SmithKline Beckman Corporation
    Inventors: Thomas R. Berka, James A. Fornwald, Joselina G. Gorniak, Martin Rosenberg, James E. Strickler, Dean P. Taylor
  • Protein protease inhibitors from streptomyces
    Patent number: 5279939
    Abstract: This invention relates to novel protein protease inhibitors as well as DNAs encoding same and vectors and transformed host cells useful for the recombinant production of the inhibitors.
    Type: Grant
    Filed: June 3, 1992
    Date of Patent: January 18, 1994
    Assignee: SmithKline Beecham Corporation
    Inventors: Thomas R. Berka, James A. Fornwald, Joselina G. Gorniak, Martin Rosenberg, James E. Strickler, Dean P. Taylor
  • Container and follow plate assembly usable with viscous material dispensers having receiving ports of two different sizes
    Patent number: 4684042
    Abstract: A container and follow plate assembly for highly viscous materials such as hand cleaner is selectively usable with dispensing devices having receiving ports of larger and smaller sizes. The preferably cylindrical container, which is sized so that one end fits the larger port, has a removable cover at that end and a fixed member closing the second end. The fixed member inlcudes a removably covered discharge opening therein which fits the smaller port. The follow plate, a one piece, preferably circular dish which is closely spaced from the inside of the container, is positioned adjacent the discharge opening end when the container is filled. The follow plate includes an integral but removable section aligned with and larger than the discharge opening.
    Type: Grant
    Filed: April 7, 1986
    Date of Patent: August 4, 1987
    Inventors: James E. Strickler, Jeffrey E. Strickler