Abstract: A device and a process for performing high temporal- and spatial-resolution MR imaging of the anatomy of a patient during intensity modulated radiation therapy (IMRT) to directly measure and control the highly conformal ionizing radiation dose delivered to the patient for the treatment of diseases caused by proliferative tissue disorders. This invention combines the technologies of open MRI, multileaf-collimator or compensating filter-based IMRT delivery, and cobalt teletherapy into a single co-registered and gantry mounted system.

Abstract: Active resistive shim coil assemblies may be used in magnetic resonance imaging (MRI) systems to reduce in-homogeneity of the magnetic field in the imaging volume. Disclosed embodiments may be used with continuous systems, gapped cylindrical systems, or vertically gapped systems. Disclosed embodiments may also be used with an open MRI system and can be used with an instrument placed in the gap of the MRI system. An exemplary embodiment of the active resistive shim coil assembly of the present disclosure includes active resistive shim coils each operable to be energized by separate currents through a plurality of power channels. In some embodiments, the disclosed active resistive shim coil assemblies allow for various degrees of freedom to shim out field in-homogeneity.

Abstract: Systems and methods for delivery of radiotherapy in conjunction with magnetic resonance imaging in which various conductors, shields and shims may be used to solve issues occurring when radiation therapy equipment is placed in the vicinity of an magnetic resonance imaging system.

Abstract: A collimating system for collimating a radiation beam having a first multileaf collimator and a second multileaf collimator configured such that the radiation beam will pass through the first multileaf collimator before passing through the second multileaf collimator, and pass through the second multileaf collimator before hitting its target. The leaves of the first multileaf collimator and the leaves of the second multileaf collimator may be configured to move independently of one another.

Abstract: Active resistive shim coil assemblies may be used in magnetic resonance imaging (MRI) systems to reduce in-homogeneity of the magnetic field in the imaging volume. Disclosed embodiments may be used with continuous systems, gapped cylindrical systems, or vertically gapped systems. Disclosed embodiments may also be used with an open MRI system and can be used with an instrument placed in the gap of the MRI system. An exemplary embodiment of the active resistive shim coil assembly of the present disclosure includes active resistive shim coils each operable to be energized by separate currents through a plurality of power channels. In some embodiments, the disclosed active resistive shim coil assemblies allow for various degrees of freedom to shim out field in-homogeneity.

Abstract: A radio frequency coil is disclosed that is suitable for use with a magnetic resonance imaging apparatus. The radio frequency coil comprises first and second conductive loops connected electrically to each other by a plurality of conductive rungs. The conductive rungs each include a section that is relatively thin that will result in less attenuation to a radiation beam than other thicker sections of the rungs. Insulating regions are also disposed in areas of the radio frequency coil that are bound by adjacent rungs and the conductive loops. Portions of the insulating regions can be configured to provide a substantially similar amount of attenuation to the radiation beam as the relatively thin sections of the conductive rungs.

Abstract: Devices and processes for performing magnetic resonance imaging of the anatomy of a patient during radiation therapy to measure and control the radiation dose delivered to the patient.

Abstract: Systems and methods for tomographic reconstruction of an image include systems and methods for producing images from k-space data. A k-space data set of an imaged object is acquired using know k-space data acquisition systems and methods. A portion of the k-space data set is sampled so as to collect some portion of the k-space data. An image is then reconstructed from the collected portion of the k-space data set according to a convex optimization model.

Abstract: A radiation therapy system comprises a magnetic resonance imaging (MRI) system combined with an irradiation system, which can include one or more linear accelerators (linacs) that can emit respective radiation beams suitable for radiation therapy. The MRI system includes a split magnet system, comprising first and second main magnets separated by gap. A gantry is positioned in the gap between the main MRI magnets and supports the linac(s) of the irradiation system. The gantry is rotatable independently of the MRI system and can angularly reposition the linac(s). Shielding can also be provided in the form of magnetic and/or RF shielding. Magnetic shielding can be provided for shielding the linac(s) from the magnetic field generated by the MRI magnets. RF shielding can be provided for shielding the MRI system from RF radiation from the linac.

Abstract: Systems and methods for the delivery of linear accelerator radiotherapy in conjunction with magnetic resonance imaging in which components of a linear accelerator may be placed in shielding containers around a gantry, may be connected with RF waveguides, and may employ various systems and methods for magnetic and radio frequency shielding.

Abstract: A magnetic resonance imaging (MRI) system includes a split magnet system having a pair of MRI magnet housings separated by gap. A pair of main MRI magnets are disposed within respective MRI magnet housings. A plurality of buttress assemblies are attached to the MRI magnet housings. Some or all of the buttress assemblies are provided with removable connections to the MRI magnet housings. This allows for partial disassembly of the MRI system for improved transport and maneuverability for relocating the MRI system. The MRI system can include a gantry in the gap for supporting a radiation therapy system. Also, the removably buttress assemblies can be used for housing conduits, such as electrical and fluid conduits, between the pair of MRI magnet housings.

Abstract: Systems and methods for tomographic reconstruction of an image include systems and methods for producing images from k-space data. A k-space data set of an imaged object is acquired using know k-space data acquisition systems and methods. A portion of the k-space data set is sampled so as to collect some portion of the k-space data. An image is then reconstructed from the collected portion of the k-space data set according to a convex optimization model.

Abstract: Systems and methods for the delivery of linear accelerator radiotherapy in conjunction with magnetic resonance imaging in which components of a linear accelerator may be placed in shielding containers around a gantry, may be connected with RF waveguides, and may employ various systems and methods for magnetic and radio frequency shielding.

Abstract: A radiation therapy system comprises a magnetic resonance imaging (MRI) system combined with an irradiation system, which can include one or more linear accelerators (linacs) that can emit respective radiation beams suitable for radiation therapy. The MRI system includes a split magnet system, comprising first and second main magnets separated by gap. A gantry is positioned in the gap between the main MRI magnets and supports the linac(s) of the irradiation system. The gantry is rotatable independently of the MRI system and can angularly reposition the linac(s). Shielding can also be provided in the form of magnetic and/or RF shielding. Magnetic shielding can be provided for shielding the linac(s) from the magnetic field generated by the MRI magnets. RF shielding can be provided for shielding the MRI system from RF radiation from the linac.

Abstract: A magnetic resonance imaging (MRI) system includes a split magnet system having a pair of MRI magnet housings separated by gap. A pair of main MRI magnets are disposed within respective MRI magnet housings. A plurality of buttress assemblies are attached to the MRI magnet housings. Some or all of the buttress assemblies are provided with removable connections to the MRI magnet housings. This allows for partial disassembly of the MRI system for improved transport and maneuverability for relocating the MRI system. The MRI system can include a gantry in the gap for supporting a radiation therapy system. Also, the removably buttress assemblies can be used for housing conduits, such as electrical and fluid conduits, between the pair of MRI magnet housings.

Abstract: Magnetic resonance (MR) guided radiation therapy (MRgRT) enables control over the delivery of radiation based on patient motion indicated by MR imaging (MRI) images captured during radiation delivery. A method for MRgRT includes: simultaneously using one or more radiation therapy heads to deliver radiation and an MRI system to perform MRI; using a processor to determine whether one or more gates are triggered based on at least a portion of MRI images captured during the delivery of radiation; and in response to determining that one or more gates are triggered based on at least a portion of the MRI images captured during the delivery of radiation, suspending the delivery of radiation.

Abstract: A radio frequency coil is disclosed that is suitable for use with a magnetic resonance imaging apparatus. The radio frequency coil comprises first and second conductive loops connected electrically to each other by a plurality of conductive rungs. The conductive rungs each include a section that is relatively thin that will result in less attenuation to a radiation beam than other thicker sections of the rungs. Insulating regions are also disposed in areas of the radio frequency coil that are bound by adjacent rungs and the conductive loops. Portions of the insulating regions can be configured to provide a substantially similar amount of attenuation to the radiation beam as the relatively thin sections of the conductive rungs.

Abstract: Devices and processes for performing magnetic resonance imaging of the anatomy of a patient during radiation therapy to measure and control the radiation dose delivered to the patient.

Abstract: A radiofrequency receive coil assembly can include a first conductive loop and a second conductive loop electrically connected at a node. The first and second conductive loops can extend into a treatment beam region of the radio frequency receive coil assembly through which one or more beams of ionizing radiation pass. The first conductive loop and the second conductive loop can overlap each other to provide electromagnetic isolation and/or can use a common conductor combined with a shared capacitor to provide electromagnetic isolation, with the shared capacitor or other electrical components, as well as any conductive loop overlaps, being positioned outside of the treatment beam region. These features can, among other possible advantages, minimize and homogenize attenuation of the beams of ionizing radiation by the radiofrequency receive coil assembly.

Abstract: Disclosed herein are methods including calibrating a radiotherapy machine to identify an effective radiation source size of a radiation source contained within the radiotherapy machine, the radiation source having a nominal radiation source size, to improve accuracy of a predicted dose profile for one or more radiation beams from the radiation source to further improve accuracy of radiation dose calculation and treatment delivery.