Abstract: Small Molecule Metabolite Reporters (SMMRs) for use as in vivo glucose biosensors, sensor compositions, and methods of use, are described. The SMMRs include boronic acid-containing xanthene, coumarin, carbostyril and phenalene-based small molecules which are used for monitoring glucose in vivo, advantageously on the skin.

Abstract: Methods, systems, and apparatus for hair treatment are disclosed which include applying treatment radiation to a skin treatment area and/or to one or more hairs to deposit energy in one or more hairs so as to modify the structure (e.g., the mechanical structure and/or the chemical structure of at least a portion of the hair(s)). The applied radiation can modify at least a portion of the hair (e.g., the hair tip) to make the hair less capable of re-entering the skin. Specifically, the proposed technique is directed to decreasing stiffness of at least portion of a hair through diminishing its flexural modulus as well as increasing the bend radius of its sharpest point. The methods and apparatus can treat and/or prevent pseudofolliculitis barbae (PFB) in the treatment area.

Abstract: Small Molecule Metabolite Reporters (SMMRs) for use as in vivo glucose biosensors, sensor compositions, and methods of use, are described. The SMMRs include boronic acid-containing xanthene, coumarin, carbostyril and phenalene-based small molecules which are used for monitoring glucose in vivo, advantageously on the skin.

Abstract: A method and apparatus are provided for treating connective tissue. The method and apparatus can be used for treating and/or reducing the appearance of cellulite.

Abstract: Small Molecule Metabolite Reporters (SMMRs) for use as in vivo glucose biosensors, sensor compositions, and methods of use, are described. The SMMRs include boronic acid-containing xanthene, coumarin, carbostyril and phenalene-based small molecules which are used for monitoring glucose in vivo, advantageously on the skin.

Abstract: Small Molecule Metabolite Reporters (SMMRs) for use as in vivo glucose biosensors, sensor compositions, and methods of use, are described. The SMMRs include boronic acid-containing xanthene, coumarin, carbostyril and phenalene-based small molecules which are used for monitoring glucose in vivo, advantageously on the skin.

Abstract: Small Molecule Metabolite Reporters (SMMRs) for use as in vivo glucose biosensors, sensor compositions, and methods of use, are described. The SMMRs include boronic acid-containing xanthene, coumarin, carbostyril and phenalene-based small molecules which are used for monitoring glucose in vivo, advantageously on the skin.

Abstract: Devices and methods of treatment of tissue, such as skin tissue, with electromagnetic radiation (EMR) are disclosed that employ local deformation of tissue in small areas. Devices and methods employing local deformation are used to produce fractional lattices of EMR-treated islets in tissue for application including hair growth management.

Abstract: Methods of treatment of tissue with electromagnetic radiation (EMR) to produce lattices of EMR-treated islets in the tissue are disclosed. Also disclosed are devices and systems for producing lattices of EMR-treated islets in tissue, and cosmetic and medical applications of such devices and systems.

Abstract: Small Molecule Metabolite Reporters (SMMRs) for use as in vivo glucose biosensors, sensor compositions, and methods of use, are described. The SMMRs include boronic acid-containing xanthene, coumarin, carbostyril and phenalene-based small molecules which are used for monitoring glucose in vivo, advantageously on the skin.

Abstract: A method of performing analysis of samples having turbidity and/or high absorbance is disclosed. The analysis utilizes information from multiple factors, which affect transmittance or absorbance. These factors include: absorbance as measured in a non-turbid sample, scattering losses due to particles and limitations of the measurement device as measured in a non-absorbing sample, additional scattering losses due to sample absorbance, variable path length effects due to the sample, variable path length effects due to the measurement device, and additional nonlinear effects. By taking into account additional factors that affect transmittance or absorbance, a more accurate analysis is achieved.

Abstract: A method for analysis of samples having turbidity and/or high absorption is disclosed. The analysis incorporates several factors that affect transmittance or absorption. These factors may include: absorption as measured in a non-turbid sample, scattering losses due to particles and limitations of the measurement device as measured in a non-absorbing sample, additional scattering losses due to sample absorption, variable path length effects due to the sample, and variable path length effects due to the measurement device. By taking into account additional factors that affect transmittance or absorption, a more accurate analysis is achieved.

Abstract: In a single-atom microlaser, a pair of opposed reflectors define a high-finesse or "high-Q" optical cavity therebetween. A source delivers a stream of multiple-energy-level atoms or particles into the cavity. Each individual atom in the stream is excited by a pump from a lower energy level to an upper energy level before injection into the cavity. The cavity resonance frequency is substantially matched to the frequency of a photon emitted by each atom as it enters the cavity. The photon is emitted due to a transition in energy between the upper level and lower level of each atom. In this manner, upon entry of a sequence of individual atoms into the cavity for example, the average number of photons resonating in the cavity exceeds one and the average number of atoms in the cavity is less than one. The photons are sustained in the high-Q cavity for a long enough time period such that the photon field interacts with the next atom in the stream.