Patents by Inventor James J Gibbons, Jr.

James J Gibbons, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of CCI-779 as an antineoplastic agent
    Patent number: 7781446
    Abstract: This invention provides the use of CCI-779 in the treatment of neoplasms.
    Type: Grant
    Filed: February 1, 2007
    Date of Patent: August 24, 2010
    Assignee: Wyeth LLC
    Inventors: Gary Dukart, James J. Gibbons, Jr., Lisa Anne Speicher, Philip Frost, Carolyn Mary Discafani-Marro
  • Method of potentiating chemotherapy and treating solid tumors
    Patent number: 7465754
    Abstract: This invention provides a method of treating solid tumors which comprises administering an effective amount of a combination of (1) a bioresponse modifier and (2) a chemotherapeutic agent. This invention also provides a method of potentiating the effects of a chemotherapeutic regimen in a mammal in need of treatment with such regimen which comprises administering a bioresponse modifier in addition to a chemotherapeutic regimen.
    Type: Grant
    Filed: September 12, 2000
    Date of Patent: December 16, 2008
    Assignee: Wyeth
    Inventors: James J. Gibbons, Jr., Gary Dukart, Judy Lucas, Lisa A. Speicher
  • Use of CCI-779 as an antineoplastic agent
    Patent number: 7189735
    Abstract: This invention provides the use of CCI-779 in the treatment of neoplasms.
    Type: Grant
    Filed: February 26, 2003
    Date of Patent: March 13, 2007
    Assignee: Wyeth
    Inventors: Gary Dukart, James J Gibbons, Jr., Lisa A Speicher, Philip Frost, Carolyn M Discafani-Marro
  • Antineoplastic combinations comprising
    Patent number: 6617333
    Abstract: This invention provides the use of a combination of CCI-779 and EKB-569 in the treatment of neoplasms.
    Type: Grant
    Filed: August 6, 2002
    Date of Patent: September 9, 2003
    Assignee: Wyeth
    Inventors: Sridhar K. Rabindran, James J. Gibbons, Jr.
  • Urethanes and ureas that induce cytokine production
    Patent number: 5658945
    Abstract: The invention relates to novel ureas and urethanes of Formula I: ##STR1## which stimulate cytokine production and may be used to accelerate recovery from neutropenia accompanying radio- or chemotherapy, bone marrow transplantation, or infections. Compounds in the invention or pharmaceutical compositions employing these compounds may be useful in the treatment of cancer, AIDS, aplastic anemia, myelodysplastic syndrome, and infectious diseases, and in the enhancement of immune response.
    Type: Grant
    Filed: May 25, 1995
    Date of Patent: August 19, 1997
    Assignee: American Cyanamid Company
    Inventors: Semiramis Ayral-Kaloustian, Steven R. Schow, Mila T. Du, James J. Gibbons, Jr.
  • Urethanes and ureas that induce cytokine production
    Patent number: 5633280
    Abstract: The invention relates to novel ureas and urethanes of Formula I: ##STR1## which stimulate cytokine production and may be used to accelerate recovery from neutropenia accompanying radio- or chemotherapy, bone marrow transplantation, or infections. Compounds in the invention or pharmaceutical compositions employing these compounds may be useful in the treatment of cancer, AIDS, aplastic anemia, myelodysplastic syndrome, and infectious diseases, and in the enhancement of immune response.
    Type: Grant
    Filed: May 25, 1995
    Date of Patent: May 27, 1997
    Assignee: American Cyanamid Company
    Inventors: Semiramis Ayral-Kaloustian, Steven R. Schow, Mila T. Du, James J. Gibbons, Jr.
  • Urethanes and ureas that enhance the growth of bone marrow progenitor cells
    Patent number: 5616612
    Abstract: The invention relates to novel ureas and urethanes of Formula I: ##STR1## which stimulate cytokine production and may be used to accelerate recovery from neutropenia accompanying radio- or chemotherapy, bone marrow transplantation, or infections. Compounds in the invention or pharmaceutical compositions employing these compounds may be useful in the treatment of cancer, AIDS, aplastic anemia, myelodysplastic syndrome, and infectious diseases, and in the enhancement of immune response.
    Type: Grant
    Filed: May 25, 1995
    Date of Patent: April 1, 1997
    Assignee: American Cyanamid Company
    Inventors: Semiramis Ayral-Kaloustian, Steven R. Schow, Mila T. Du, James J. Gibbons, Jr.
  • Urethanes and ureas that induce cytokine production
    Patent number: 5602275
    Abstract: The invention relates to novel ureas and urethanes of Formula I: ##STR1## which stimulate cytokine production and may be used to accelerate recovery from neutropenia accompanying radio- or chemotherapy, bone marrow transplantation, or infections. Compounds in the invention or pharmaceutical compositions employing these compounds may be useful in the treatment of cancer, AIDS, aplastic anemia, myelodysplastic syndrome, and infectious diseases, and in the enhancement of immune response.
    Type: Grant
    Filed: May 25, 1995
    Date of Patent: February 11, 1997
    Assignee: American Cyanamid Company
    Inventors: Semiramis Ayral-Kaloustian, Steven R. Schow, Mila T. Du, James J. Gibbons, Jr.
  • Urethanes and ureas that induce cytokine production
    Patent number: 5545662
    Abstract: The invention relates to novel ureas and urethanes of Formula I: ##STR1## which stimulate cytokine production and may be used to accelerate recovery from neutropenia accompanying radio- or chemotherapy, bone marrow transplantation, or infections. Compounds in the invention or pharmaceutical compositions employing these compounds may be useful in the treatment of cancer, AIDS, aplastic anemia, myelodysplastic syndrome, and infectious diseases, and in the enhancement of immune response.
    Type: Grant
    Filed: March 14, 1994
    Date of Patent: August 13, 1996
    Assignee: American Cyanamid Company
    Inventors: Semiramis Ayral-Kaloustian, Steven R. Schow, Mila T. Du, James J. Gibbons, Jr
  • Urethanes and ureas that induce cytokine production
    Patent number: 5312831
    Abstract: The invention relates to novel ureas and urethanes of Formula I: ##STR1## which stimulate cytokine production and may be used to accelerate recovery from neutropenia accompanying radio- or chemotherapy, bone marrow transplantation, or infections. Compounds in the invention or pharmaceutical compositions employing these compounds may be useful in the treatment of cancer, AIDS, aplastic anemia, myelodysplastic syndrome, and infectious diseases, and in the enhancement of immune response.
    Type: Grant
    Filed: May 12, 1993
    Date of Patent: May 17, 1994
    Assignee: American Cyanamid Company
    Inventors: Semiramis Ayral-Kaloustian, Steven R. Schow, Mila T. Du, James J. Gibbons, Jr.
  • Treatment of neoplasms with CCI-779/EKB-569 combination
    Patent number: RE40418
    Abstract: This invention provides the use of a combination of CCI-779 and EKB-569 in the treatment of neoplasms.
    Type: Grant
    Filed: September 8, 2005
    Date of Patent: July 1, 2008
    Assignee: Wyeth
    Inventors: Sridhar K. Rabindran, James J. Gibbons, Jr.