Abstract: A pallet wrapper and imaging system a pallet loaded with containers to calculate a sustainability based upon a type of the pallet and the containers on the pallet. The system also determines the stability of the pallet and containers, a speed at which the pallet and containers can be wrapped, and an amount of stretch film needed to secure the load for transport. After validation by the imaging system (with or without a wrapper), a QC bot assists a QC worker in remedying or checking any detected errors or potential errors.

Abstract: An improved device and system for facilitating polymerase chain reaction including a light source, detector, waveguide, and filters that occupy minimal space and facilitate detection of stationary samples, reduced sample read time, and simultaneous reading of multiple light wavelengths.

Abstract: The present application relates to plasma cells and plasma cell precursors that express a macromolecule, such as a protein, protein mimetic or a peptide and compositions comprising these plasma cells or plasma cell precursors. The application further relates to methods of using and making the plasma cells and plasma cell precursors that express the macromolecule. Methods of treatment comprising administering the plasma cells or plasma cell precursors are also contemplated.

Abstract: The invention provides a method of treating a tumor in a human patient comprising (i) identifying a patient as having a LAG-3 positive tumor and (ii) administering to the patient a PD-1 pathway inhibitor, a combination of a PD1 pathway inhibitor and an immune checkpoint inhibitor, a combination of a LAG-3 inhibitor and a PD-1 pathway inhibitor, or an anti-CTLA4 antibody. In some embodiments, the method further comprises identifying the patient as having a LAG-3 positive PD-L1 positive tumor. In some embodiments, the LAG-3 inhibitor is an anti-LAG-3 antibody and the PD-1 pathway inhibitor is an anti-PD-1 antibody. The methods of the invention can improve response rates to treatment with a PD-1 pathway inhibitor, a combination of a PD1 pathway inhibitor and an immune checkpoint inhibitor, or a combination of a LAG-3 inhibitor and a PD-1 pathway inhibitor.

Abstract: A system and method of irrigation control calculates a predicted soil moisture value based that is compared to low moisture threshold. If the predicted soil moisture value is a value below the low moisture threshold value, the next irrigation cycle or scheduled irrigation operation is allowed to proceed or otherwise activated. The predicted soil moisture value may be calculated by adjusting a current soil moisture value by a historical adjustment factor based on negative net changes in soil moisture values.

Abstract: A formation detection system comprising: (a) one or more sensors and (b) one or more lights that illuminate a location of interest so that the one or more sensors can monitor the location of interest; wherein one of the one or more sensors are located substantially planar with a wire of a paper machine and proximate to a slice opening so that the one of the one or more sensors is adjacent to a cut through so that the one of the one or more sensors is capable of measuring stock above the wire and removed water below the wire, and wherein the one of the one or more sensors is capable of measuring a distance between an impingement location of a stock jet and the wire from a forming board.

Abstract: Methods of characterizing an analyte using a detector such as a nanopore and an enzyme are provided. One aspect features methods for characterizing a double-stranded polynucleotide using a detector, e.g., without using a hairpin connecting a template and a complement of the double-stranded polynucleotide. Another aspect features methods for characterizing an analyte using a tag-modified nanopore with increased sensitivity and/or higher throughput. Compositions and systems including, e.g., adaptors for attachment to double-stranded polynucleotides and tag-modified nanopores, which can be used in the methods are also provided.

Abstract: An automated dental drill includes a dental drill housing that includes a mouth piece housing section and a one or more degrees of freedom drive housing section; an end effector drive support having a shaft section that is at least partially positioned in the mouth piece housing section, and an end effector for the cutting of a native tooth or dental appliance to a desired tolerance. The end effector is positioned on the end effector drive support. The automated dental drill also includes a power source that drives the end effector and is coupled to the end effector and a one or more degrees of freedom drive assembly to direct the end effector along one or more degrees of freedom relative to the mouth piece housing section.

Abstract: The present disclosure relates a device that includes a rotary union body. Included with the rotary union body is a circumferential air channel, a seal channel, and an intake air channel. The intake air channel is connected to the circumferential air channel. Also disclosed is a hub assembly system that includes a hub and a rotary union body. Included with the rotary union body is a circumferential air channel, a seal channel and an intake air channel. Here the intake air channel is connected to the circumferential air channel.

Abstract: A set of commands for each of a plurality of actuators to alter an aircraft's state responsive to one or more inputs is produced. The set of commands is provided to fewer than all actuators comprising the plurality of actuators.

Abstract: A set of commands for each of a plurality of actuators to alter an aircraft's state responsive to one or more inputs is produced. The set of commands is provided to fewer than all actuators comprising the plurality of actuators.

Abstract: Provided herein are tooth clamping systems, methods, and kits for performing a dental procedure with a dental cutting machine guided by three-dimensional data associated with an impression of one or more teeth of a patient.

Abstract: In one example, a method performed by a processing system including at least one processor includes acquiring information about a first physical environment of a first user of an extended reality environment, acquiring information about a second physical environment of a second user of the extended reality environment, rendering the extended reality environment in a manner that is compatible with both the first physical environment and the second physical environment, based on the information about the first physical environment and the information about the second physical environment, and applying a first adjustment to a presentation of the XR environment that is displayed to the first user, based on the information about the first physical environment, without making the first adjustment to a presentation of the XR environment that is displayed to the second user.

Abstract: An apparatus having an agent that includes a processor and a memory coupled with the processor and communicates with at least one of a fault, configuration, accounting, performance, security module. The processor effectuates operations including determining that a service is operating properly. The processor further effectuates operations including if the service is operating properly and the service is disabled, enabling the service. The processor further effectuates operations including if the service is not operating properly, generating an alarm and if the service is enabled, disabling the service.

Abstract: Embodiments described herein relate to an apparatus for positioning and securing an excised biological tissue specimen for imaging and analysis. In some embodiments, an apparatus includes a sample bag defining an inner volume configured to receive a biological tissue sample, and a sealing member coupled to the sample bag. An imaging window is disposed and configured to be placed in contact with at least a portion of the biological tissue sample, and a positioning member is coupled to the imaging window and is configured to be disposed against the sealing member to substantially seal the inner volume. The positioning member includes a vacuum port disposed and configured to be aligned with a vacuum source to withdraw air from the inner volume of the sample bag.

Abstract: Methods and systems provide for assessing likelihood of market success of a flavor. One embodiment of a method includes (a) collecting input information from a consumer regarding at least one food related preference; (b) analyzing the input information using a computer algorithm in order to assign the consumer to one of a plurality of distinct consumer segments based on the consumer's food related preferences; (c) collecting input information from the consumer regarding preference level of at least one flavor for a particular consumable product; (d) analyzing the input information and assigning the preference level of the at least one flavor within each distinct consumer segment; and (e) determining the impact of the at least one flavor within each distinct consumer segment.

Abstract: A humidification system can include a heater base, a chamber, and a breathing circuit. The heater base includes a heater plate positioned in a recessed region, and a heat conductive portion of the chamber is configured to contact the heater plate. The heater base includes a guard configured to control movement of the chamber into and out of the recessed region. The guard includes an anti-racking mechanism. The chamber includes an inlet port, an outlet port. A downward extension extends into the chamber from the inlet port, and a baffle is disposed at a lower end of the downward extension. A component of the breathing circuit can include a conduit hanging end cap for shipping and storage. The end cap can include a hanging component to allow the breathing circuit component to be hung from a medical stand. The system can detect when breathing circuits are connected in reverse.

Abstract: An apparatus having an agent that includes a processor and a memory coupled with the processor and communicates with at least one of a fault, configuration, accounting, performance, security module. The processor effectuates operations including determining that a service is operating properly. The processor further effectuates operations including if the service is operating properly and the service is disabled, enabling the service. The processor further effectuates operations including if the service is not operating properly, generating an alarm and if the service is enabled, disabling the service.

Abstract: Aspects of the subject disclosure may include, for example, identifying user preferences for an XR application executing at an XR user system, wherein the user preferences are associated with an XR application user, accessing a historical profile associated with the XR application user, receiving local environment information from a sensor array of the XR user system, selecting an XR object for presentation on an XR display of the XR user system based on the local environment information, the user preferences, and the historical profile, and allocating compute resources to facilitate a rendering of the XR object, wherein the allocated compute resources are selected from a compute resource pool comprising local compute resources of the XR user system and edge compute resources of a network. Other embodiments are disclosed.

Abstract: Aspects of the subject disclosure may include, for example, receiving information about a task to be completed by a user, receiving information about the user and receiving information about a physical environment of the user. The subject disclosure may further include creating one or more immersion objects based on the information about the task, the information about the user and the information about the physical environment, creating an immersive environment including the one or more immersive objects and at least a portion of the physical environment of the user, and communicating to an extended reality (XR) device of the user information about the immersive environment to create an immersive experience for completion of the task by the user. Other embodiments are disclosed.