Patents by Inventor James Jiang
James Jiang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240156975Abstract: Compositions and methods for the treatment of viral infections include conjugates containing inhibitors of viral neuraminidase (e.g., zanamivir, peramivir, or analogs thereof) linked to an Fc monomer, an Fc domain, and Fc-binding peptide, an albumin protein, or albumin-binding peptide. In particular, conjugates can be used in the treatment of viral infections (e.g., influenza viral infections).Type: ApplicationFiled: September 11, 2023Publication date: May 16, 2024Inventors: James M. BALKOVEC, Daniel C. BENSEN, Allen BORCHARDT, Thomas P. BRADY, Zhi-Yong CHEN, Jason COLE, Quyen-Quyen Thuy DO, Simon DOEHRMANN, Wanlong JIANG, Thanh LAM, Alain NONCOVICH, Leslie W. TARI
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Patent number: 11977895Abstract: Examples described herein relate to a graphics processing unit (GPU) coupled to the memory device, the GPU configured to: execute an instruction thread; determine if a dual directional signal barrier is associated with the instruction thread; and based on clearance of the dual directional signal barrier for a particular signal barrier identifier and a mode of operation, indicate a clearance of the dual directional signal barrier for the mode of operation, wherein the dual directional signal barrier is to provide a single barrier to gate activity of one or more producers based on activity of one or more consumers or gate activity of one or more consumers based on activity of one or more producers.Type: GrantFiled: December 22, 2020Date of Patent: May 7, 2024Assignee: Intel CorporationInventors: Sabareesh Ganapathy, Fangwen Fu, Hong Jiang, James Valerio
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Patent number: 11972749Abstract: A wearable sound device includes a venting device including a film structure and an actuator and a driving circuit configured to be controlled by a controller and to drive the actuator, such that the film structure is controlled to form a vent or to seal the vent. The controller is coupled to a sensing device configured to generate a sensing result and determine whether to seal the vent according to the sensing result. The film structure partitions a space within the wearable sound device into a first volume and a second volume. The first volume is connected to or to be connected to an ear canal of a wearable sound device user. The second volume is connected to or to be connected to an ambient of the wearable sound device. The first volume and the second volume are connected via the vent when the vent is formed.Type: GrantFiled: April 20, 2023Date of Patent: April 30, 2024Assignee: xMEMS Labs, Inc.Inventors: James Wargnier, Michael David Housholder, Yanchen Lu, JengYaw Jiang
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Patent number: 11963928Abstract: Disclosed herein are glass pharmaceutical vials having sidewalls of reduced thickness. In embodiments, the glass pharmaceutical vial may include a glass body comprising a sidewall enclosing an interior volume. An outer diameter D of the glass body is equal to a diameter d1 of a glass vial of size X as defined by ISO 8362-1, wherein X is one of 2R, 3R, 4R, 6R, 8R, 10R, 15R, 20R, 25R, 30R, 50R, and 100R as defined by ISO 8362-1. However, the sidewall of the glass pharmaceutical vial comprises an average wall thickness Ti that is less than or equal to 0.85*s1, wherein s1 is a wall thickness of the glass vial of size X as defined by ISO 8362-1 and X is one of 2R, 3R, 4R, 6R, 8R, 10R, 15R, 20R, 25R, 30R, 50R, and 100R as defined by ISO 8362-1.Type: GrantFiled: May 2, 2023Date of Patent: April 23, 2024Assignee: CORNING INCORPORATEDInventors: James Ernest Webb, Sinue Gomez-Mower, Weirong Jiang, Joseph Michael Matusick, Christie Leigh McCarthy, Connor Thomas O'Malley, John Stephen Peanasky, Shivani Rao Polasani, Steven Edward DeMartino, Michael Clement Ruotolo, Jr., Bryan James Musk, Jared Seaman Aaldenberg, Eric Lewis Allington, Douglas Miles Noni, Jr., Amber Leigh Tremper, Kristen Dae Waight, Kevin Patrick McNelis, Patrick Joseph Cimo, Christy Lynn Chapman, Robert Anthony Schaut, Adam Robert Sarafian
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Patent number: 11964988Abstract: Provided herein are compounds of the Formula (I): (I) and tautomers, stereoisomers and pharmaceutically acceptable salts and solvates thereof, wherein Rx, Ry, W, X, Y, Z, Ring A and (AA) have the meanings given in the specification, which are inhibitors of RET kinase and are useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, including RET-associated diseases and disorders.Type: GrantFiled: September 6, 2019Date of Patent: April 23, 2024Assignee: ARRAY BIOPHARMA INC.Inventors: James F. Blake, Donghua Dai, Julia Haas, Yutong Jiang, Dean Kahn, Gabrielle R. Kolakowski, Elizabeth A. McFaddin, Megan L McKenney, Andrew T. Metcalf, David A. Moreno, Brett Prigaro, Ginelle A. Ramann, Li Ren, Shane M. Walls, Hailong Zhang
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Patent number: 11963929Abstract: Disclosed herein are glass pharmaceutical vials having sidewalls of reduced thickness. In embodiments, the glass pharmaceutical vial may include a glass body comprising a sidewall enclosing an interior volume. An outer diameter D of the glass body is equal to a diameter d1 of a glass vial of size X as defined by ISO 8362-1, wherein X is one of 2R, 3R, 4R, 6R, 8R, 10R, 15R, 20R, 25R, 30R, 50R, and 100R as defined by ISO 8362-1. However, the sidewall of the glass pharmaceutical vial comprises an average wall thickness Ti that is less than or equal to 0.85*s1, wherein s1 is a wall thickness of the glass vial of size X as defined by ISO 8362-1 and X is one of 2R, 3R, 4R, 6R, 8R, 10R, 15R, 20R, 25R, 30R, 50R, and 100R as defined by ISO 8362-1.Type: GrantFiled: May 2, 2023Date of Patent: April 23, 2024Assignee: CORNING INCORPORATEDInventors: Connor Thomas O'Malley, Sinue Gomez-Mower, Weirong Jiang, Joseph Michael Matusick, Christie Leigh McCarthy, Christy Lynn Chapman, John Stephen Peanasky, Shivani Rao Polasani, James Ernest Webb, Michael Clement Ruotolo, Jr., Bryan James Musk, Jared Seaman Aaldenberg, Eric Lewis Allington, Douglas Miles Noni, Jr., Amber Leigh Tremper, Kristen Dae Waight, Kevin Patrick McNelis, Patrick Joseph Cimo, Steven Edward DeMartino, Robert Anthony Schaut, Adam Robert Sarafian
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Publication number: 20240124453Abstract: Compounds of Formula I or a stereoisomer, tautomer, prodrug or pharmaceutically acceptable salt thereof are provided, which are useful for the treatment of hyperproliferative diseases. Methods of using compounds of Formula I or a stereoisomer, tautomer, prodrug or pharmaceutically acceptable salt thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.Type: ApplicationFiled: November 17, 2023Publication date: April 18, 2024Applicant: Array BioPharma Inc.Inventors: James Francis BLAKE, Mark Laurence BOYS, Mark Joseph CHICARELLI, Adam Wade COOK, Mohamed S. A. ELSAYED, Jay Bradford FELL, John P. FISCHER, Ronald Jay HINKLIN, Yutong JIANG, Oren Teague MCNULTY, Macedonio J. MEJIA, Martha E. RODRIGUEZ, Christina Elizabeth WONG
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Patent number: 11952408Abstract: Provided are binding molecules, such as TCRs or antigen binding fragments thereof and antibodies and antigen-binding fragments thereof, such as those that recognize or bind human papilloma virus (HPV) 16, including HPV 16 E6 and HPV 16 E7. Also provided are engineered cells containing such binding molecules, compositions containing the binding molecules or engineered cells, and methods of treatment, such as administration of the binding molecules, engineered cells, or compositions.Type: GrantFiled: September 28, 2018Date of Patent: April 9, 2024Assignees: Juno Therapeutics, Inc., Editas Medicine, Inc.Inventors: Cameron Brandt, Brian Belmont, Christopher Borges, Stephen Michael Burleigh, Alexandra Croft, Stephen Jacob Goldfless, David Jeffrey Huss, Yue Jiang, Timothy G. Johnstone, David Koppstein, Hieu Nguyen, Christopher Heath Nye, Haley Peper, Blythe D. Sather, Sonia Timberlake, Dean Y. Toy, Queenie Vong, Gordon Grant Welstead, James Sissons
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Publication number: 20240111075Abstract: Embodiments described herein relate to flat optical devices with a coating layer including monolayers selected from the group consisting of molybdenum disulfide (MoS2), tungsten disulfide (WS2), tungsten diselenide (WSe2), molybdenum diselenide (MoSe2), molybdenum ditelluride (MoTe2), titanium disulfide (TlS2), zirconium disulfide (ZrS2), zirconium diselenide (ZrSe2), hafnium disulfide (HfS2), platinum disulfide (PtS2), tin disulfide (SnS2), or combinations thereof. The coating layer is disposed over a plurality of optical device structures of the optical device. The monolayers may alternate between the materials to form the coating layer or may be a uniform coating layer of a single material. The coating layer is disposed over each optical device structure of the plurality of optical device structures.Type: ApplicationFiled: January 31, 2022Publication date: April 4, 2024Inventors: Russell Chin Yee TEO, James CONNOLLY, Chien-An CHEN, Andrew CEBALLOS, Jing JIANG, Jhenghan YANG, Yongan XU
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Publication number: 20240105089Abstract: Electronic displays and electronic devices including such electronic displays and antennas are provided for improved transmission of signals through circuitry of the electronic display. The electronic display may include multiple power supply tiles that are separated with non-conductive gaps to reduce circulation of eddy currents induced by the transmission signals. Moreover, voltage supply routing paths within the power supply tiles may be grouped to provide non-conductive gaps within the power supply tiles. Accordingly, the antenna may provide the transmission signals through the electronic display with improved efficiency based on reducing surface currents (e.g., eddy currents) on the electronic display.Type: ApplicationFiled: September 19, 2023Publication date: March 28, 2024Inventors: William Matthew Pender Paul, Mario Martinis, Jiayi Jin, Yongjie Jiang, Baris Posat, Mojtaba Fallahpour, Haitao Li, James G. Horiuchi, Giovanni Azzellino, Weijun Yao, Stanley B. Wang, Mahdi Farrokh Baroughi
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Publication number: 20240106137Abstract: Connector receptacles that can provide a robust and reliable connection to a board and have a small form factor. An example can provide connector receptacles that provide a robust and reliable connection to a board by providing contacts having highly planarized solder tails. The solder tails can be supported by extensions of housing portions to provide consistent placement and alignment, as well an amount of shock absorption. The solder tails can include chamfered surfaces to improve soldered connections to pads of a board. The chamfered surfaces can also enable a reduced pitch between solder tails thereby helping to provide a reduced form factor.Type: ApplicationFiled: September 23, 2022Publication date: March 28, 2024Applicant: Apple Inc.Inventors: James M. Jeon, Mahmoud R. Amini, Marc Soriano Baliarda, Tianrun Jiang
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Publication number: 20240095424Abstract: Aspects of the disclosure are directed to automatically determining floor planning in chips, which factors in memory macro alignment. A deep reinforcement learning (RL) agent can be trained to determine optimal placements for the memory macros, where memory macro alignment can be included as a regularization cost to be added to the placement objective as a RL reward. Tradeoffs between the placement objective and alignment of macros can be controlled by a tunable alignment parameter.Type: ApplicationFiled: August 18, 2022Publication date: March 21, 2024Inventors: Ebrahim Mohammadgholi Songhori, Shen Wang, Azalia Mirhoseini, Anna Goldie, Roger Carpenter, Wenjie Jiang, Young-Joon Lee, James Laudon
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Publication number: 20240066029Abstract: Provided herein are compounds of the Formula I: and stereoisomers and pharmaceutically acceptable salts or solvates thereof, in which A, B, X1, X2, X3, X4, Ring D, and E have the meanings given in the specification, which are inhibitors of RET kinase and are useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, including RET-associated diseases and disorders.Type: ApplicationFiled: June 27, 2023Publication date: February 29, 2024Inventors: Steven W. ANDREWS, Sean ARONOW, James F. Blake, Barbara J. BRANDHUBER, Adam COOK, Julia HAAS, Yutong JIANG, Gabrielle R. KOLAKOWSKI, Elizabeth A. MCFADDIN, Megan L. MCKENNEY, Oren T. MCNULTY, Andrew T. METCALF, David A. MORENO, Tony P. TANG, Li REN
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Patent number: 11353318Abstract: Disclosed is an optical probe system that is capable of high speed, high precision, and high resolution 3D digitalization of engineered objects. The 3D dimensional data of the engineered object is measured using a swept source optical coherence tomography system with improved speed, spatial resolutions, and depth range. Also disclosed is a type of coordinate measurement machine (CMM) that is capable of performing high speed, high resolution, and non-contact measurement of engineered objects. The mechanic stylus in the touch-trigger probe of a conventional CMM is replaced with an optical stylus with reconfigurable diameter and length. The distance from the center of the optical stylus to the measurement probe is optically adjusted to match the height of the object to be measured quickly, which eliminates one dimensional movement of the probe and greatly improves the productivity.Type: GrantFiled: December 16, 2020Date of Patent: June 7, 2022Assignee: Thorlabs, Inc.Inventors: James Jiang, Alex Cable
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Publication number: 20210102799Abstract: Disclosed is an optical probe system that is capable of high speed, high precision, and high resolution 3D digitalization of engineered objects. The 3D dimensional data of the engineered object is measured using a swept source optical coherence tomography system with improved speed, spatial resolutions, and depth range. Also disclosed is a type of coordinate measurement machine (CMM) that is capable of performing high speed, high resolution, and non-contact measurement of engineered objects. The mechanic stylus in the touch-trigger probe of a conventional CMM is replaced with an optical stylus with reconfigurable diameter and length. The distance from the center of the optical stylus to the measurement probe is optically adjusted to match the height of the object to be measured quickly, which eliminates one dimensional movement of the probe and greatly improves the productivity.Type: ApplicationFiled: December 16, 2020Publication date: April 8, 2021Inventors: James JIANG, Alex CABLE
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Patent number: 10890431Abstract: Disclosed is an optical probe system that is capable of high speed, high precision, and high resolution 3D digitalization of engineered objects. The 3D dimensional data of the engineered object is measured using a swept source optical coherence tomography system with improved speed, spatial resolutions, and depth range. Also disclosed is a type of coordinate measurement machine (CMM) that is capable of performing high speed, high resolution, and non-contact measurement of engineered objects. The mechanic stylus in the touch-trigger probe of a conventional CMM is replaced with an optical stylus with reconfigurable diameter and length. The distance from the center of the optical stylus to the measurement probe is optically adjusted to match the height of the object to be measured quickly, which eliminates one dimensional movement of the probe and greatly improves the productivity.Type: GrantFiled: December 10, 2019Date of Patent: January 12, 2021Assignee: Thorlabs, Inc.Inventors: James Jiang, Alex Cable
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Patent number: 10796711Abstract: A dynamic optical microphone system may include an acoustic microphone that receives an audio signal and a laser microphone that transmits a laser beam and receives optical feedback from a human struck by the laser beam. The system may include a depth sensor that determines a distance to the human and a camera that tracks human faces. A processor may be communicatively coupled to the acoustic microphone, laser microphone, depth sensor, camera, and a memory storing computer executable instructions. The processor may determine a direction to a human, direct the laser beam at a voice box of the human, determine a distance to the human using the depth sensor, adjust an intensity of the laser beam based on the distance, receive optical feedback and isolate a voice signal through the optical feedback from background noise in the audio signal.Type: GrantFiled: September 29, 2017Date of Patent: October 6, 2020Assignee: HONDA MOTOR CO., LTD.Inventors: James Jiang, Rahul Khanna
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Publication number: 20200109938Abstract: Disclosed is an optical probe system that is capable of high speed, high precision, and high resolution 3D digitalization of engineered objects. The 3D dimensional data of the engineered object is measured using a swept source optical coherence tomography system with improved speed, spatial resolutions, and depth range. Also disclosed is a type of coordinate measurement machine (CMM) that is capable of performing high speed, high resolution, and non-contact measurement of engineered objects. The mechanic stylus in the touch-trigger probe of a conventional CMM is replaced with an optical stylus with reconfigurable diameter and length. The distance from the center of the optical stylus to the measurement probe is optically adjusted to match the height of the object to be measured quickly, which eliminates one dimensional movement of the probe and greatly improves the productivity.Type: ApplicationFiled: December 10, 2019Publication date: April 9, 2020Inventors: James JIANG, Alex CABLE
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Patent number: 10557701Abstract: Disclosed is an optical probe system that is capable of high speed, high precision, and high resolution 3D digitalization of engineered objects. The 3D dimensional data of the engineered object is measured using a swept source optical coherence tomography system with improved speed, spatial resolutions, and depth range. Also disclosed is a type of coordinate measurement machine (CMM) that is capable of performing high speed, high resolution, and non-contact measurement of engineered objects. The mechanic stylus in the touch-trigger probe of a conventional CMM is replaced with an optical stylus with reconfigurable diameter and length. The distance from the center of the optical stylus to the measurement probe is optically adjusted to match the height of the object to be measured quickly, which eliminates one dimensional movement of the probe and greatly improves the productivity.Type: GrantFiled: March 24, 2017Date of Patent: February 11, 2020Assignee: Thorlabs, Inc.Inventors: James Jiang, Alex Cable
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Patent number: 10281256Abstract: An agile optical imaging system for optical coherence tomography imaging using a tunable source comprising a wavelength tunable VCL laser is disclosed. The tunable source has long coherence length and is capable of high sweep repetition rate, as well as changing the sweep trajectory, sweep speed, sweep repetition rate, sweep linearity, and emission wavelength range on the fly to support multiple modes of OCT imaging. The imaging system also offers new enhanced dynamic range imaging capability for accommodating bright reflections. Multiscale imaging capability allows measurement over orders of magnitude dimensional scales. The imaging system and methods for generating the waveforms to drive the tunable laser in flexible and agile modes of operation are also described.Type: GrantFiled: April 3, 2017Date of Patent: May 7, 2019Assignees: THORLABS, INC., PRAEVIUM RESEARCH, INC.Inventors: Alex Ezra Cable, Vijaysekhar Jayaraman, James Jiang, Benjamin Potsaid