Patents by Inventor James John Ragghianti
James John Ragghianti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20170042104Abstract: The present disclosure provides a method for propagating a crop using meristem excision, micropropagation, plantlet formation, plantlet singulation, plantlet transfer to artificial seeds, and planting artificial seeds. Methods are provided for producing and handling the plantlets and materials used to form artificial seeds. The artificial seeds may be used to store plantlets or may be planted to form a crop.Type: ApplicationFiled: April 23, 2015Publication date: February 16, 2017Inventors: Timothy Casper, Charles Philip Defelice, David L. Hallahan, Bruno Ieiri Ito, Sharon Jo Keeler, Katrina Kratz, Markus Michael Liedgens, Brian D. Mather, Scott Meadows, Marcos Luciano Nunhez, Joseph Anthony Perrotto, Eduardo Da Cruz Maduro Picelli, Laudenir Maria Prioli, James John Ragghianti, Christopher C. Whitcombe
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Patent number: 8815566Abstract: Engineered strains of the oleaginous yeast Yarrowia lipolytica capable of producing greater than 25% eicosapentaenoic acid (EPA, an ?-3 polyunsaturated fatty acid) in the total oil fraction are described. These strains comprise various chimeric genes expressing heterologous desaturases, elongases and acyltransferases and optionally comprise various native desaturase and acyltransferase knockouts to enable synthesis and high accumulation of EPA. Production host cells are claimed, as are methods for producing EPA within said host cells.Type: GrantFiled: July 17, 2013Date of Patent: August 26, 2014Assignee: E I du Pont de Nemours and CompanyInventors: Howard Glenn Damude, Peter John Gillies, Daniel Joseph Macool, Stephen K Picataggio, Dana M. Walters Pollak, James John Ragghianti, Zhixiong Xue, Narendra S Yadav, Hongxiang Zhang, Quinn Qun Zhu
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Patent number: 8685682Abstract: An engineered strain of the oleaginous yeast Yarrowia lipolytica capable of producing greater than 5.6% docosahexaenoic acid acid (DHA, an w-3 polyunsaturated fatty acid) in the total oil fraction is described. This strain comprises various chimeric genes expressing heterologous desaturases, elongases and acyltransferases and optionally comprises various native desaturase and acyltransferase knockouts to enable synthesis and high accumulation of DHA. Production host cells are claimed, as are methods for producing DHA within said host cells.Type: GrantFiled: May 14, 2009Date of Patent: April 1, 2014Assignee: E I du Pont de Nemours and CompanyInventors: Howard Glenn Damude, Peter John Gillies, Daniel Joseph Macool, Stephen K Picataggio, James John Ragghianti, John E Seip, Zhixiong Xue, Narendra S Yadav, Hongxiang Zhang, Quinn Qun Zhu
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Publication number: 20140030772Abstract: Engineered strains of the oleaginous yeast Yarrowia lipolytica capable of producing greater than 25% eicosapentaenoic acid (EPA, an ?-3 polyunsaturated fatty acid) in the total oil fraction are described. These strains comprise various chimeric genes expressing heterologous desaturases, elongases and acyltransferases and optionally comprise various native desaturase and acyltransferase knockouts to enable synthesis and high accumulation of EPA. Production host cells are claimed, as are methods for producing EPA within said host cells.Type: ApplicationFiled: July 17, 2013Publication date: January 30, 2014Applicant: E I DU PONT DE NEMOURS AND COMPANYInventors: Howard Glenn Damude, Peter John Gillies, Daniel Joseph Macool, Stephen K. Picataggio, Dana M. Walters Pollak, James John Ragghianti, Zhixiong Xue, Narendra S. Yadav, Hongxiang Zhang, Quinn Qun Zhu
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Patent number: 8518674Abstract: Engineered strains of the oleaginous yeast Yarrowia lipolytica capable of producing greater than 25% eicosapentaenoic acid (EPA, an ?-3 polyunsaturated fatty acid) in the total oil fraction are described. These strains comprise various chimeric genes expressing heterologous desaturases, elongases and acyltransferases and optionally comprise various native desaturase and acyltransferase knockouts to enable synthesis and high accumulation of EPA. Production host cells are claimed, as are methods for producing EPA within said host cells.Type: GrantFiled: September 29, 2010Date of Patent: August 27, 2013Assignee: E I du Pont de Nemours and CompanyInventors: Howard Glenn Damude, Peter John Gillies, Daniel Joseph Macool, Stephen K. Picataggio, Dana M. Walters Pollak, James John Ragghianti, Zhixiong Xue, Narendra S. Yadav, Hongxiang Zhang, Quinn Qun Zhu
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Patent number: 7932077Abstract: Engineered strains of the oleaginous yeast Yarrowia lipolytica capable of producing greater than 25% eicosapentaenoic acid (EPA, an ?-3 polyunsaturated fatty acid) in the total oil fraction are described. These strains comprise various chimeric genes expressing heterologous desaturases, elongases and acyltransferases and optionally comprise various native desaturase and acyltransferase knockouts to enable synthesis and high accumulation of EPA. Production host cells are claimed, as are methods for producing EPA within said host cells.Type: GrantFiled: November 2, 2005Date of Patent: April 26, 2011Assignee: E. I. du Pont de Nemours and CompanyInventors: Howard Glenn Damude, Peter John Gillies, Daniel Joseph Macool, Stephen K. Picataggio, Dana M. Walters Pollak, James John Ragghianti, Zhixiong Xue, Narendra S. Yadav, Hongxiang Zhang, Quinn Qun Zhu
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Publication number: 20110086919Abstract: Engineered strains of the oleaginous yeast Yarrowia lipolytica capable of producing greater than 25% eicosapentaenoic acid (EPA, an ?-3 polyunsaturated fatty acid) in the total oil fraction are described. These strains comprise various chimeric genes expressing heterologous desaturases, elongases and acyltransferases and optionally comprise various native desaturase and acyltransferase knockouts to enable synthesis and high accumulation of EPA. Production host cells are claimed, as are methods for producing EPA within said host cells.Type: ApplicationFiled: September 29, 2010Publication date: April 14, 2011Applicant: E. I. Du Pont De Nemours and CompanyInventors: Howard Glenn Damude, Peter John Gillies, Daniel Joseph Macool, Stephen K. Picataggio, Dana M. Walters Pollak, James John Ragghianti, Zhixiong Xue, Narendra S. Yadav, Hongxiang Zhang, Quinn Qun Zhu
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Publication number: 20100022647Abstract: Engineered strains of the oleaginous yeast Yarrowia lipolytica capable of producing greater than 10% arachidonic acid (ARA, an ?-6 polyunsaturated fatty acid) in the total oil fraction are described. These strains comprise various chimeric genes expressing heterologous desaturases, elongases and acyltransferases, and optionally comprise various native desaturase and acyltransferase knockouts to enable synthesis and high accumulation of ARA. Production host cells are claimed, as are methods for producing ARA within said host cells.Type: ApplicationFiled: July 30, 2009Publication date: January 28, 2010Applicant: E. I. DU PONT DE NEMOURS AND COMPANYInventors: Howard Glenn Damude, Peter John Gillies, Daniel Joseph Macool, Stephen K. Picataggio, Dana M. Walters Pollak, James John Ragghianti, Zhixiong Xue, Narendra S. Yadav, Hongxiang Zhang, Quinn Qun Zhu
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Publication number: 20090311380Abstract: An engineered strain of the oleaginous yeast Yarrowia lipolytica capable of producing greater than 5.6% docosahexaenoic acid acid (DHA, an w-3 polyunsaturated fatty acid) in the total oil fraction is described. This strain comprises various chimeric genes expressing heterologous desaturases, elongases and acyltransferases and optionally comprises various native desaturase and acyltransferase knockouts to enable synthesis and high accumulation of DHA. Production host cells are claimed, as are methods for producing DHA within said host cells.Type: ApplicationFiled: May 14, 2009Publication date: December 17, 2009Applicant: E.I. DU PONT DE NEMOURS AND COMPANYInventors: Howard Glenn Damude, Peter John Gillies, Daniel Joseph Macool, Stephen K. Picataggio, James John Ragghianti, John E. Seip, Zhixiong Xue, Narendra S. Yadav, Hongxiang Zhang, Quinn Qun Zhu
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Patent number: 7588931Abstract: Engineered strains of the oleaginous yeast Yarrowia lipolytica capable of producing greater than 10% arachidonic acid (ARA, an ?-6 polyunsaturated fatty acid) in the total oil fraction are described. These strains comprise various chimeric genes expressing heterologous desaturases, elongases and acyltransferases, and optionally comprise various native desaturase and acyltransferase knockouts to enable synthesis and high accumulation of ARA. Production host cells are claimed, as are methods for producing ARA within said host cells.Type: GrantFiled: November 1, 2005Date of Patent: September 15, 2009Assignee: E. I. du Pont de Nemours and CompanyInventors: Howard Glenn Damude, Peter John Gillies, Daniel Joseph Macool, Stephen K. Picataggio, Dana M. Walters Pollak, James John Ragghianti, Zhixiong Xue, Narendra S. Yadav, Hongxiang Zhang, Quinn Qun Zhu
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Patent number: 7550286Abstract: An engineered strain of the oleaginous yeast Yarrowia lipolytica capable of producing greater than 5.6% docosahexaenoic acid acid (DHA, an w-3 polyunsaturated fatty acid) in the total oil fraction is described. This strain comprises various chimeric genes expressing heterologous desaturases, elongases and acyltransferases and optionally comprises various native desaturase and acyltransferase knockouts to enable synthesis and high accumulation of DHA. Production host cells are claimed, as are methods for producing DHA within said host cells.Type: GrantFiled: November 1, 2005Date of Patent: June 23, 2009Assignee: E. I. du Pont de Nemours and CompanyInventors: Howard Glenn Damude, Daniel Joseph Macool, Stephen K. Picataggio, James John Ragghianti, John E. Seip, Zhixiong Xue, Narendra S. Yadav, Hongxiang Zhang, Quinn Qun Zhu