Abstract: An article is described herein that includes: a substrate having a glass, glass-ceramic or a ceramic composition and comprising a primary surface; and a protective film disposed on the primary surface. The protective film comprises a thickness of greater than 1.5 microns and a maximum hardness of greater than 15 GPa at a depth of 500 nanometers, as measured on the film disposed on the substrate. Further, the protective film comprises a metal oxynitride that is graded such that an oxygen concentration in the film varies by 1.3 or more atomic %. In addition, the substrate comprises an elastic modulus less than an elastic modulus of the film.

Abstract: Spacecraft servicing devices or pods and related methods may include a body configured to be deployed from a host spacecraft at a location adjacent a target spacecraft and at least one spacecraft servicing component configured to perform at least one servicing operation on the target spacecraft.

Abstract: A non-radioactive homogenous plasma ion source that is power efficient with greater electrode life longevity and performance (homogenous low temperature plasma for ion formation, stability, robustness) than alternative non-radioactive ion sources for generating analyte ions of either positive or negative charge. Its compact design minimizes the spacing between electrodes, reducing the power requirements needed to ignite and maintain plasma levels. The non-radioactive plasma ion source generally comprises a housing for retaining a uniquely designed ion source that generates a uniform distribution of plasma to maximize the generation of ions at a lower plasma temperature to minimize undesirable nitrogen oxide and ozone gasses, at least one planar electrode in one embodiment, a mounting head with a gas exhaust, and a chamber with a counterflow gas inlet, and an analyte gas inlet.

Abstract: An article is described herein that includes: a glass-based substrate comprising opposing major surfaces; a crack mitigating composite over one of the major surfaces, the composite comprising an inorganic element and a polymeric element; and a hard film disposed on the crack mitigating composite comprising an elastic modulus greater than or equal to the elastic modulus of the glass-based substrate. The crack mitigating composite is characterized by an elastic modulus of greater than 30 GPa. Further, the hard film comprises at least one of a metal-containing oxide, a metal-containing oxynitride, a metal-containing nitride, a metal-containing carbide, a silicon-containing polymer, a carbon, a semiconductor, and combinations thereof.

Abstract: Systems and methods are described for generating a transcript of a legal proceeding or other multi-speaker conversation or performance in real time or near-real time using multi-channel audio capture. Different speakers or participants in a conversation may each be assigned a separate microphone that is placed in proximity to the given speaker, where each audio channel includes audio captured by a different microphone. Filters may be applied to isolate each channel to include speech utterances of a different speaker, and these filtered channels of audio data may then be processed in parallel to generate speech-to-text results that are interleaved to form a generated transcript.

Abstract: Provided herein are compounds of Formula (I), their pharmaceutically acceptable salts, and their pharmaceutical compositions: wherein R1, R2, R3a, R3b, R4, R5, and A are defined in the present disclosure. The compounds are potent inhibitors of the main protease (Mpro) of severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2), and they are useful in treating or preventing COVID-19 in a subject.

Abstract: Embodiments provide an electric aircraft with a plurality of lift fan assemblies that are configured to provide vertical lift, and one or more pusher propellers that are configured to provide forward thrust. The lift fan assemblies may be coupled to the wings of the aircraft via one or more support structures, and the wings may be coupled to an upper region of the fuselage. The pusher propeller(s) may be coupled to a tailing end of the fuselage. The lift fan assemblies and the pusher propeller(s) may provide thrust and movement in directions that are orthogonal to one another. A control system coupled to the aircraft may control the lift fan assemblies and the one or more pusher propellers to activate, increase in power, and decrease in power. The lift fan assemblies and the one or more pusher propellers may be operated separately, and may be active at different times.

Abstract: A wheat variety designated 6PBTL06B, the plants and seeds of wheat variety 6PBTL06B, methods for producing a wheat plant produced by crossing the variety 6PBTL06B with another wheat plant, and hybrid wheat seeds and plants produced by crossing the variety 6PBTL06B with another wheat line or plant, and the creation of variants by backcrossing, mutagenesis or transformation of variety 6PBTL06B are disclosed. Methods for producing other wheat varieties or breeding lines derived from wheat variety 6PBTL06B and to wheat varieties or breeding lines produced by those methods are also provided.

Abstract: Presenting first drawer area on a first display device in an instrument panel of a vehicle, the first drawer area presented in an extended state; presenting second drawer area on a second display device in the instrument panel of the vehicle, the second drawer area presented in a retracted state; receiving first transition command regarding the first and second drawer areas; and in response to receiving the first transition command: presenting the first drawer area in the retracted state on the first display device, wherein the first content is not visible in the first drawer area in the retracted state; and presenting the second drawer area in the extended state on the second display device, wherein the first content of the first application is visible in the second drawer area.

Abstract: Medical articles formed from ionically bonding an ionic compound and an active agent provide enhanced properties. The ionic compound comprises an ionic additive incorporated into a base polymer. The ionic additive may be one or more of an anionic additive, a cationic additive, and a zwitterionic additive. Medical articles herein have antimicrobial, anti-fouling, and/or antithrombotic characteristics.

Abstract: An article that includes: an inorganic oxide substrate having opposing major surfaces; and an optical film structure disposed on a first major surface of the substrate, the optical film structure comprising one or more of a silicon-containing oxide, a silicon-containing nitride and a silicon-containing oxynitride and a physical thickness from about 50 nm to less than 500 nm. The article exhibits a hardness of 8 GPa or greater measured at an indentation depth of about 100 nm or a maximum hardness of 9 GPa or greater measured over an indentation depth range from about 100 nm to about 500 nm, the hardness and the maximum hardness measured by a Berkovich Indenter Hardness Test. Further, the article exhibits a single-side photopic average reflectance that is less than 1%.

Abstract: Methods, apparatus, systems, and articles of manufacture are disclosed. An example system includes: interface circuitry; programmable circuitry; and instructions to program the programmable circuitry to: obtain audio of a media presentation; obtain ambient noise in an area associated with the media presentation; determine an intensity of a difference between the audio and the ambient noise; and determine an engagement level of an audience of the media presentation based on a duration the intensity satisfies a threshold value.

Abstract: A computing system includes a network interface circuit structured to facilitate data transmission over a network, and at least one processing circuit configured to receive account information from a provider device via an input/output device of the provider device, the account information corresponding with a user account, generate a first code including a first unique identifier specific to the account information, the first code being configured to be captured by a user device to cause a browser or an application to launch on the user device, receive a user confirmation from the user device in response to the first code being captured by the user device, the user confirmation including the first unique identifier, determine the first unique identifier received with the user confirmation corresponds with the account information, and open the user account in response to confirming the first unique identifier corresponds with the account information.

Abstract: An assembly includes a dash and a deployable panel supported by the dash. The deployable panel is moveable relative to the dash from an undeployed position to a deployed position. The deployable panel has a proximal end at the dash in the deployed position and a distal end spaced above the dash in the deployed position. An airbag is supported by the dash and is inflatable to an inflated position. The airbag abuts the deployable panel when the deployable panel is in the deployed position and the airbag is in the inflated position. A tether extends from the airbag to the deployable panel in the undeployed position.

Abstract: A display article is described herein that includes: a substrate comprising a thickness and a primary surface; a textured surface region; and an antireflective coating disposed on the textured surface region. The textured surface region comprises structural features and an average texture height (Rtext) from 50 nm to 300 nm. The substrate exhibits a sparkle of less than 5%, as measured by PPD140, and a transmittance haze of less than 40%, at a 0° incident angle. The antireflective coating comprises alternating high refractive index and low refractive index layers. Each of the low index layers comprises a refractive index of less than or equal to 1.8, and each of the high index layers comprises a refractive index of greater than 1.8. The article also exhibits a first-surface average photopic specular reflectance (% R) of less than 0.3% at any incident angle from about 5° to 20° from normal at visible wavelengths.

Abstract: The techniques herein are directed generally to a “zero-knowledge” data management network. Users are able to share verifiable proof of data and/or identity information, and businesses are able to request, consume, and act on the data—all without a data storage server or those businesses ever seeing or having access to the raw sensitive information (where server-stored data is viewable only by the intended recipients, which may even be selected after storage). In one embodiment, source data is encrypted with a source encryption key (e.g., source public key), with a rekeying key being an encrypting combination of a source decryption key (e.g., source private key) and a recipient's public key. Without being able to decrypt the data, the storage server can use the rekeying key to re-encrypt the source data with the recipient's public key, to then be decrypted only by the corresponding recipient using its private key, accordingly.

Abstract: Antibody molecule-drug conjugates (ADCs) that specifically bind to lipopolysaccharides (LPS) are disclosed. The antibody molecule-drug conjugates can be used to treat, prevent, and/or diagnose bacterial infections and related disorders.

Abstract: Medical articles formed from ionically bonding an ionic compound and an active agent provide enhanced properties. The ionic compound comprises an ionic additive incorporated into a base polymer. The ionic additive may be one or more of an anionic additive, a cationic additive, and a zwitterionic additive. Medical articles herein have antimicrobial, anti-fouling, and/or antithrombotic characteristics.

Abstract: Compounds that inhibit KRas G12D. In particular, compounds that inhibit the activity of KRas G12D, pharmaceutical compositions comprising the compounds and methods of use therefor, and in particular, methods of treating cancer. The compounds have a general structure represented by Formula (I): or a pharmaceutically acceptable salt thereof.