Patents by Inventor James Kacmar

James Kacmar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120205311
    Abstract: The present invention relates to methods and systems for optimization of dilution of a viscous starting material to isolate and/or concentrate the product of interest from the starting source material such that the process minimizes the volume of diluent and the total volume of the waste stream generated during the process as well as maximizing the yield of desired product. The system employs cross-flow filtration modules with sub-channels that are equidistant to the inlet and outlet of said modules and such modules are characterized by optimal channel height, optimal transmembrane pressure, etc., which are selected in order to achieve the best combination of product quality and production yield.
    Type: Application
    Filed: January 21, 2010
    Publication date: August 16, 2012
    Applicant: SMARTFLOW TECHNOLOGIES, INC.
    Inventors: Henry B. Kopf, James A. Kacmar
  • Publication number: 20110309018
    Abstract: The present invention relates to methods and systems for optimization of dilution of a viscous starting material to isolate and/or concentrate the product of interest from the starting source material such that the process minimizes the volume of diluent and the total volume of the waste stream generated during the process as well as maximizing the yield of desired product. The system employs cross-flow filtration modules with sub-channels that are equidistant to the inlet and outlet of said modules and such modules are characterized by optimal channel height, optimal transmembrane pressure, etc., which are selected in order to achieve the best combination of product quality and production yield.
    Type: Application
    Filed: January 21, 2010
    Publication date: December 22, 2011
    Applicant: SMARTFLOW TECHNOLOGIES, INC.
    Inventors: Henry B. Kopf, James A. Kacmar
  • Patent number: 7901937
    Abstract: A continuous flow bioreactor system that includes a bioreactor, an optional post-bioreactor preparation chamber, a cell sorter, and an optional pre-bioreactor preparation chamber in a closed loop, useful for enriching a heterogeneous cell population growing in the bioreactor with an isolated subpopulation of cells.
    Type: Grant
    Filed: November 3, 2008
    Date of Patent: March 8, 2011
    Assignee: Regents of the University of Minnesota
    Inventors: Friedrich Srienc, Abdelqader Zamamiri, Nicholas R. Abu-Absi, James A. Kacmar
  • Publication number: 20090081770
    Abstract: A continuous flow bioreactor system that includes a bioreactor, an optional post-bioreactor preparation chamber, a cell sorter, and an optional pre-bioreactor preparation chamber in a closed loop, useful for enriching a heterogeneous cell population growing in the bioreactor with an isolated subpopulation of cells.
    Type: Application
    Filed: November 3, 2008
    Publication date: March 26, 2009
    Applicant: Regents of the University of Minnesota
    Inventors: FRIEDRICH SRIENC, Abdelqader Zamamiri, Nicholas R. Abu-Absi, James A. Kacmar
  • Publication number: 20040214314
    Abstract: A continuous flow bioreactor system that includes a bioreactor, an optional post-bioreactor preparation chamber, a cell sorter, and an optional pre-bioreactor preparation chamber in a closed loop, useful for enriching a heterogeneous cell population growing in the bioreactor with an isolated subpopulation of cells.
    Type: Application
    Filed: November 1, 2002
    Publication date: October 28, 2004
    Inventors: Friedrich Srienc, Abdelqader Zamamiri, Nicholas R. Abu-Absi, James A. Kacmar