Abstract: A method, an apparatus, a system, and a computer program product for processing messages. A computer system parses a message to identify key value pairs for confidential information in the message. The computer system creates a redacted message in which values in the key value pairs identified for the confidential information are replaced with plaintext tags. The computer system stores the key value pairs in a secure database. The computer system stores the redacted message in a plaintext database.

Abstract: Provided are cathepsin inhibitor compounds and pharmaceutically acceptable salts thereof, and combinations thereof, for use in the treatment or prophylaxis of viral disease in an animal.

Abstract: An imaging device may have an array of image pixels that includes red, green, blue, and infrared pixels. The imaging device may include a dual-band filter that allows transmission of light in the visible band and in the near-infrared band and may include color processing circuitry that produces a color image with marked infrared regions. The color processing circuitry may include a standard color processing pipeline with a color correction matrix that produces a tone-mapped standard red, green, and blue image and may include infrared marking circuitry. The infrared marking circuitry may include hue angle determination circuitry, cell means determination circuitry, and near-infrared determination circuitry that determine portions of the image with high infrared reflectance to be marked. The infrared-marked tone-mapped standard red, green, and blue image may be output to a machine vision system to identify objects in the imaged scene with high infrared reflection.

Abstract: The present invention encompasses embodiments in which a therapeutic antibody is conjugated to ?-1,6-glucan oligomers. Thus, the present invention includes, among other things, compositions including a therapeutic antibody conjugated to one or more ?-1,6-glucan oligomers. The present invention further includes, among other things, methods of making and/or using such ?-1,6-glucan conjugates. In certain embodiments, a ?-1,6-glucan conjugate of the present invention is useful as a therapeutic or in a method of therapy.

Abstract: The present invention relates to a method for detecting a pathogen in cellular lysate by measuring pathogen-specific enzyme activity. The method comprises contacting the cellular lysate with a substrate the pathogen of interest recognizes and modifies, and obtaining a measurable, recordable, signal. The method may comprise detection of SARS-CoV viruses using the activity of SARS PLpro enzyme in tongue scrape lysate as a readout.

Abstract: The present invention relates to a method for detecting a pathogen in cellular lysate by measuring pathogen-specific enzyme activity. The method comprises contacting the cellular lysate with a substrate the pathogen of interest recognizes and modifies, and obtaining a measurable, recordable, signal. The method may comprise detection of SARS-CoV viruses using the activity of SARS PLpro enzyme in tongue scrape lysate as a readout.

Abstract: A monolithic nonplanar ring oscillator (NPRO) laser with a large piezo-electric tuning range and high frequency slew rate, denoted as a ?NPRO, is described. A tuning range of 3.5 GHz with 192 volts applied, corresponding to a tuning coefficient of 18.2 MHz/volt was experimentally demonstrated. This performance was achieved by making the solid-state gain element small, with a small distance between a piezo-electric element bonded to the solid-state gain element and a first lase plane in the solid-state gain element. The entire nonplanar ring lasing path within the solid-state gain element may lie within the half of the solid-state gain element closest to the bonded piezo-electric element. This large frequency modulation span and wide frequency modulation bandwidth, combined with unsurpassed coherence and high power, make this an attractive laser for frequency-modulated continuous-wave (FMCW) LIDAR.

Abstract: A passively Q-switched laser with adjustable pulse parameters and a method of controlling the pulse parameters is described. The laser has a pumped spot size in a gain element that may be adjusted to control the pulse energy. The laser has a laser resonator that may have a variable resonator length to control the pulse duration.

Abstract: A passively Q-switched laser with intracavity pumping is described. The passively Q-switched laser has an optically pumped gain element and a saturable absorber element. The optically pumped gain element is situated in an extended cavity of a VECSEL (Vertical Extended Cavity Surface Emitting Laser) so that the gain element is pumped by a circulating pump beam of the VECSEL. The passively Q-switched laser may produce output pulses at an eye-safe wavelength using a low gain laser transition and may use a plurality of surface emitting gain regions to pump the passively Q-switched laser.

Abstract: The present invention relates to a method for detecting a pathogen in cellular lysate by measuring pathogen-specific enzyme activity. The method comprises contacting the cellular lysate with a substrate the pathogen of interest recognizes and modifies, and obtaining a measurable, recordable, signal. The method may comprise detection of SARS-CoV viruses using the activity of SARS PLpro enzyme in tongue scrape lysate as a readout.

Abstract: A laser resonator assembly and a method of assembly of the laser resonator assembly are described. The laser resonator assembly has a gain element and an output coupler that are placed in a gain element frame and output coupler frame, respectively. The output coupler may also be a saturable absorber element so that the laser resonator assembly emits Q-switched pulses. The frames provide heat dissipation and can be easily aligned and permanently affixed in an appropriate alignment. A laser using the laser resonator assembly can be assembled in a low-cost manner.

Abstract: A passively, Q-switched laser is described. The laser may operate at an eye-safe lasing wavelength of 1.34 microns and use a gain element of Nd:YVO4 and a saturable absorber element of V:YAG with a space separating the gain element and saturable absorber element. The Q-switched laser is pumped by a grating stabilized laser diode. The laser may be used in laser ranging applications.

Abstract: The present disclosure provides methods and systems that may be used for providing quality control for audio samples. The audio samples may be speech samples of a user. The user may be participating in an audio interview.

Abstract: A passively, Q-switched laser operating at an eye safe wavelength of between 1.2 and 1.4 microns is described. The laser may operate at a lasing wavelength of 1.34 microns and use a gain element of Nd:YVO4 and a saturable absorber element of V:YAG. The systems and methods to produce short pulses having a pulse duration less than 1 ns and high energy pulses having pulse energies greater than 2 ?J are described.

Abstract: A frequency modulated, continuous wave (FMCW) laser using a microchip gain medium, an optical coupling element, and a tuning element is described. The laser may be part of a coherent laser ranging system.

Abstract: A passively, Q-switched laser operating at an eye safe wavelength of between 1.2 and 1.4 microns is described. The laser may operate at a lasing wavelength of 1.34 microns and use a gain element of Nd:YVO4 and a saturable absorber element of V:YAG. The position of the resonator axial mode spectrum relative to a gain peak of the gain element is controlled to yield desired characteristics in the laser output.

Abstract: The present disclosure provides methods and systems that may be used for providing quality control for audio samples. The audio samples may be speech samples of a user. The user may be participating in an audio interview.

Abstract: The present disclosure provides methods and systems that may be used for providing quality control for audio samples. The audio samples may be speech samples of a user. The user may be participating in an audio interview.

Abstract: An imaging device may have an array of image pixels that includes red, green, blue, and infrared pixels. The imaging device may include a dual-band filter that allows transmission of light in the visible band and in the near-infrared band and may include color processing circuitry that produces a color image with marked infrared regions. The color processing circuitry may include a standard color processing pipeline with a color correction matrix that produces a tone-mapped standard red, green, and blue image and may include infrared marking circuitry. The infrared marking circuitry may include hue angle determination circuitry, cell means determination circuitry, and near-infrared determination circuitry that determine portions of the image with high infrared reflectance to be marked. The infrared-marked tone-mapped standard red, green, and blue image may be output to a machine vision system to identify objects in the imaged scene with high infrared reflection.

Abstract: The present invention relates to a method for detecting a pathogen in cellular lysate by measuring pathogen-specific enzyme activity. The method comprises contacting the cellular lysate with a substrate the pathogen of interest recognizes and modifies, and obtaining a measurable, recordable, signal. The method may comprise detection of SARS-CoV viruses using the activity of SARS PLpro enzyme in tongue scrape lysate as a readout.