Patents by Inventor James Kutney

James Kutney has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel sterol/stanol phosphorylnitroderivatives and use thereof in treating or preventing cardiovascular disease, its underlying conditions and other disorders
    Publication number: 20070232688
    Abstract: Sterol and stanol phosphorylnitro derivatives and their use in treating or preventing cardiovascular disease, its underlying conditions and other disorders are disclosed. The disclosed compounds include a phosphate linker, at least one moiety that releases nitric oxide (NO), and a sterol or stanol moiety. Some compounds additionally include an ascorbyl moiety to make the compound more readily soluble in aqueous and non-aqueous media.
    Type: Application
    Filed: April 3, 2006
    Publication date: October 4, 2007
    Inventors: Patricia Orchansky, James Kutney
  • Novel sterol/stanol nitroderivatives and use thereof in treating or preventing cardiovascular disease, its underlying conditions and other disorders
    Publication number: 20070232580
    Abstract: Sterol and stanol nitro derivatives and their use in treating or preventing cardiovascular disease, its underlying conditions and other disorders are disclosed. The disclosed nitro derivatives are synthesized by ester linkage of a nitric oxide (NO)-releasing moiety to a sterol or stanol compound.
    Type: Application
    Filed: April 3, 2006
    Publication date: October 4, 2007
    Inventors: Patricia Orchansky, James Kutney
  • Compositions comprising one or more policosanols and/or policosanoic acids combined with sterol and/or steroid based ascorbic acid derivatives, and uses thereof
    Publication number: 20050234025
    Abstract: A composition comprises one or more long chain alcohols (policosanols) and/or their respective acids (policosanoic acids) and one or more ascorbic acid derivatives, including all biologically acceptable salts or solvates or prodrugs of at least one such derivative or of the salts or of the solvates thereof and is used for the treatment and prevention of a variety of conditions and disorders.
    Type: Application
    Filed: April 20, 2004
    Publication date: October 20, 2005
    Inventors: James Kutney, Laura Wessman
  • Anhydrovinblastine for the treatment of cancer
    Publication number: 20030162803
    Abstract: The present invention is particularly directed to the use of a derivative of vinblastine, 3′,4′-dehydrovinblastine (3′,4′-anhydrovinblastine: AHVB), which differs from vinblastine in that it possesses a double bond at the 3′,4′ position of the catharanthine nucleus rather than the hydroxyl group that is present in the parent structure, in the treatment of cancer.
    Type: Application
    Filed: November 15, 2002
    Publication date: August 28, 2003
    Inventors: Bruce Schmidt, James Kutney, Lawrence Mayer
  • Anhydrovinblastine for the treatment of cancer
    Publication number: 20020103218
    Abstract: The present invention is particularly directed to the use of a derivative of vinblastine, 3′,4′-dehydrovinblastine (3′,4′-anhydrovinblastine: AHVB), which differs from vinblastine in that it possesses a double bond at the 3′, 4′ position of the catharanthine nucleus rather than the hydroxyl group that is present in the parent structure, in the treatment of cancer.
    Type: Application
    Filed: September 4, 2001
    Publication date: August 1, 2002
    Applicant: University of British Columbia
    Inventors: Bruce Schmidt, James Kutney, Lawrence Mayer
  • Anhydrovinblastine for the treatment of cancer
    Patent number: 6326376
    Abstract: The present invention is particularly directed to the use of a derivative of vinblastine, 3′,4′-anhydrovinblastine (AHVB), which differs from vinblastine in that it possesses a double bond at the 3′,4′ position of the caranthine nucleus rather than the hydroxyl group that is present in the parent structure, as an anti-neoplastic agent in the therapeutic treatment of cancer.
    Type: Grant
    Filed: January 21, 2000
    Date of Patent: December 4, 2001
    Assignee: University of British Columbia
    Inventors: Bruce Schmidt, James Kutney, Lawrence Mayer
  • Use of anhydrovinblastine
    Patent number: 6011041
    Abstract: The present invention is particularly directed to the use of a derivative of vinblastine, 3',4'-anhydrovinblastine (AHVB), which differs from vinblastine in that it possesses a double bond at the 3',4' position of the caranthine nucleus rather than the hydroxyl group that is present in the parent structure, as an antineoplastic agent in the therapeutic treatment of cancer. Specifically, the treatment of lymphoma with 3',4'-anhydrovinblastine is disclosed.
    Type: Grant
    Filed: July 26, 1996
    Date of Patent: January 4, 2000
    Assignee: University of British Columbia
    Inventors: Bruce Schmidt, James Kutney, Lawrence Mayer