Patents by Inventor James L. Colony

James L. Colony has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Macrocyclic chelating agent
    Patent number: 5583219
    Abstract: A novel bifunctional macrocyclic chelating agent useful for attaching metal ions to proteins, polypeptides and other polymers. These reagents are unique in their ability to bind a variety of metal ions and to yield a high metal ion concentration per protein molecule. Protein metal chelates thus obtained will have useful radiophysical, chemical, fluorescent, photochemical and magnetic properties suitable for biomedical applications.
    Type: Grant
    Filed: April 28, 1995
    Date of Patent: December 10, 1996
    Assignee: Akzo Nobel N.V.
    Inventors: Ramaswamy Subramanian, James L. Colony
  • Bifunctional chelating agents
    Patent number: 5488126
    Abstract: A new series of bifunctional chelating agents useful for attaching metal ions to proteins, polypeptides and other polymers and methods for their preparation are described. These reagents are unique in their ability to bind a variety of metal ions and to yield a high metal ion concentration per protein molecule. Using these methods polymeric analogs of these bifunctional chelating agents called Starburst ligands can also be obtained. Protein metal chelates thus obtained will have useful radiophysical, chemical, fluorescent, photochemical and magnetic properties suitable for biomedical applications.
    Type: Grant
    Filed: February 16, 1994
    Date of Patent: January 30, 1996
    Assignee: Akzo Nobel N.V.
    Inventors: Ramaswamy Subramanian, James L. Colony