Abstract: An adjustable, knotless button/loop/needle construct for fixation of cranial cruciate ligament deficient stifle. The adjustable, knotless construct includes two fixation devices (for example, two buttons), at least one flexible, adjustable loop attached to at least one of the fixation devices (e.g., the buttons), and two needles (each needle being attached to one fixation device, e.g., the buttons). The adjustable, knotless construct has an adjustable loop length and allows adjustment in one direction while preventing or locking the construct from loosening in the opposite direction, due to applied tensile forces. The construct and technique of the present invention provides an improved knotless system for cruciate ligament repair.

Abstract: Techniques, mixtures, mixing and delivery kits, and improved delivery instruments for implantation of micronized allograft tissue over a microfractured defect. Allograft cartilage tissue is delivered over a cartilage defect that has been debrided and microfractured, without the need for a periosteal covering or separate type of patch sewn over the top. The allograft tissue may be any micronized cartilage particulates obtained by various methods, for example, cartilage delivered in its native form, dehydrated via lyophilization, “freeze-dried,” dehydrated via desiccation, or dehydrated by any other method.

Abstract: Implants for resurfacing or repairing one or more articular cartilage bearing surfaces of a biological organism include an engineered tissue and a biocompatible porous substrate secured to the engineered tissue for attaching the implant to a native bone of the biological organism. The engineered tissue includes a scaffold containing a biocompatible material, and a plurality of living chondrocytes supported by the scaffold. Methods for culturing chondrocytes for incorporation into a biocompatible implant are provided. A bioreactor for producing functional cartilaginous tissue from a cell-seeded scaffold and a system for producing functional cartilaginous tissue are also provided.

Abstract: Instrumentation and assembly for arthroscopic elbow surgery which includes a humeral component. The humeral component is installed in a trough formed in the humeral condyle. The trough may be formed by using a plurality of drill pins and a plurality of corresponding cutters (and optionally a template). The two drill pins are passed through the template and drilled into the humerus, and cutters are advanced over the corresponding drill pins to form the trough. The humeral component may be employed in conjunction with an ulnar implant.

Abstract: Methods and instrumentation for arthroscopic elbow surgery which include a humeral component. The humeral component is installed in a trough formed in the humeral condyle. The trough may be formed by using a plurality of drill pins and a plurality of corresponding cutters (and optionally a template). The two drill pins are passed through the template and drilled into the humerus, and cutters are advanced over the corresponding drill pins to form the trough. The humeral component may be employed in conjunction with an ulnar implant.

Abstract: A suture needle construct and method for extracapsular ligament reconstruction in mammals. The joint is first is first explored, and the damaged ligament and meniscus are debrided. The joint capsule is closed and a tunnel is created at the appropriate location in the proximal tibia for tibial fixation. Subsequent to the formation of the tibial tunnel, a suture having a substantially curved needle at one end and a substantially straight needle at the other end is brought in the proximity of the joint. The suture is passed around the lateral fabella using the substantially curved needle, then deep to the patellar ligament using the substantially straight needle, and through the tibial tunnel using the straight needle. The needles are cut off, and the sutures are tensioned over repair site.

Abstract: The present invention provides a method and apparatus for tissue, such as an allograft, storage and preservation for extended periods of time at room temperature in a sterile tissue culture chamber. The invention further provides a process for maintaining the sterility of tissue using the apparatus as described.

Abstract: An apparatus and method for stabilization of a cranial cruciate ligament deficient stifle in canines using a suture-button construct.

Abstract: Biomarkers, biomarker panels and methods for diagnosing osteoarthritis (OA) are disclosed, using measurement of the expression level of certain polypeptides in a test sample from a subject, including MCP1, IL8, KC, MMP2, MMP3, IL6, MMP1, RANTES, MMP9, IL1B, Apolipoprotein A1, Apolipoprotein E, DCN, CILP and COMP. Related methods for monitoring OA treatment efficacy, diagnostic reagents, and kits are also described.

Abstract: An apparatus and method for stabilization of a cranial cruciate ligament deficient stifle in canines using a suture-button construct.

Abstract: A method for stabilization of a cranial cruciate ligament in canines using a suture-button construct. The method includes the steps of drilling a hole across the femur and the tibia, passing a needle with a pull-through suture strand through the femoral hole, and applying a tensile force to the pull-through suture strand and a suture tape such that a first button lies sideways for passage through the femoral hole, advancing the first button through the femoral hole until the first button exits the femoral hole, passing the needle with the pull-through suture strand through the tibial hole, applying a tensile force to the pull-through suture strand and the suture tape such that the first button lies sideways for passage through the tibial hole, flipping the first button to engage it against the tibia, pulling free ends of the suture tape to advance a second button and to seat and secure it against the femur.

Abstract: Implants for resurfacing or repairing one or more articular cartilage bearing surfaces of a biological organism include an engineered tissue and a biocompatible porous substrate secured to the engineered tissue for attaching the implant to a native bone of the biological organism. The engineered tissue includes a scaffold containing a biocompatible material, and a plurality of living chondrocytes supported by the scaffold. Methods for culturing chondrocytes for incorporation into a biocompatible implant are provided. A bioreactor for producing functional cartilaginous tissue from a cell-seeded scaffold and a system for producing functional cartilaginous tissue are also provided.

Abstract: Methods and instrumentation for arthroscopic elbow surgery which include a humeral component. The humeral component is installed in a trough formed in the humeral condyle. The trough may be formed by using a plurality of drill pins and a plurality of corresponding cutters (and optionally a template). The two drill pins are passed through the template and drilled into the humerus, and cutters are advanced over the corresponding drill pins to form the trough. The humeral component may be employed in conjunction with an ulnar implant.

Abstract: A prosthetic elbow for replacing an elbow of a dog or a human to restore normal, pain-free joint function. The elbow includes a humeral component for attachment to a humerus and a radioulnar component for attachment to an ulna. The humeral component includes a generally cylindric spool having a contoured external surface defining a first articular surface. The radioulnar component has a generally U-shaped contour with an inner peripheral surface defining a second articular surface sized and shaped for engagement with the first articular surface. Positional guides provide for implantation at precise locations.

Abstract: An apparatus and method for stabilization of a cranial cruciate ligament deficient stifle in canines using a suture-button construct.

Abstract: A carrier for fishing accessories which can be worn without interfering with the fishing operation, whether standing, sitting, or walking. Broadly, the carrier includes a pouch, carrying mechanism and fishing rod suspension device. The pouch is capable of holding many different types of fishing accessories. The versatile carrying mechanism, such as, an adjustable shoulder strap and waist strap, allows the fisherman to wear the pouch on the hip, back or shoulder, and on either the right side or left side of the body. The fishing rod suspension device supports and suspends the fishing rod from the pouch thereby freeing the fisherman's hands for rigging the line or performing other fishing operations. The carrier may also include a work surface, such as a magnetic plate, to hold fishing accessories such as flies, hooks, lures, weights, and tools.

Abstract: The apparatus is comprised of a platform from which a player may drive a ball into an enclosure. A sloping floor is provided to return balls to a reservoir placed under the platform. A teeing mechanism operated by a player presents balls one at a time to a tee. The mechanism is comprised of a pneumatic system with master and servo bellows.