Patents by Inventor James M. Seckler

James M. Seckler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR STIMULATING VENTILATORY AND/OR RESPIRATORY DRIVE
    Publication number: 20230338319
    Abstract: A method of stimulating ventilatory and/or respiratory drive in a subject in need thereof includes administering to the subject a therapeutically effective amount of a composition comprising an glutathione alkyl ester, adduct thereof, or pharmaceutically acceptable salt, tautomer, or solvate thereof.
    Type: Application
    Filed: March 16, 2022
    Publication date: October 26, 2023
    Inventors: Stephen J. Lewis, Michael W. Jenkins, James M. Seckler
  • COMPOSITIONS AND METHODS FOR ATTENUATING OPIOID INDUCED CARDIO AND/OR RESPIRATORY DEPRESSION
    Publication number: 20220387407
    Abstract: A method of attenuating opioid induced cardio and/or respiratory depression in a subject in need thereof includes administering to the subject an amount of a composition comprising a nitroxide compound effective to attenuate the opioid induced cardio and/or respiratory depression.
    Type: Application
    Filed: August 5, 2022
    Publication date: December 8, 2022
    Inventors: Stephen J. Lewis, James M. Seckler
  • Sensor for detection of analytes
    Patent number: 11422131
    Abstract: A sensor for the detection of an analyte in a fluid includes an electrode having a detection surface, a polydopamine layer adhered to the electrode detection surface; and optionally a receptor chemically functionalized to the polydopamine of the detection surface of the electrode. The receptor selectively binds to the analyte of interest and the analyte once bound is detectable by measuring the change of capacitance of the electrode.
    Type: Grant
    Filed: February 12, 2018
    Date of Patent: August 23, 2022
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: James M. Seckler, Neil A. Goldsmith, Stephen J. Lewis, Corey Smith, James Bates, Nicole Meyers, Spencer T. Burton
  • SENSOR FOR DETECTION OF ANALYTES
    Publication number: 20180164240
    Abstract: A sensor for the detection of an analyte in a fluid includes an electrode having a detection surface, a polydopamine layer adhered to the electrode detection surface; and optionally a receptor chemically functionalized to the polydopamine of the detection surface of the electrode. The receptor selectively binds to the analyte of interest and the analyte once bound is detectable by measuring the change of capacitance of the electrode.
    Type: Application
    Filed: February 12, 2018
    Publication date: June 14, 2018
    Inventors: James M. Seckler, Neil A. Goldsmith, Stephen J. Lewis, Corey Smith, James Bates, Nicole Meyers, Spencer T. Burton